A randomized, prospective study comparing once-daily gentamicin versus thrice-daily gentamicin in the treatment of puerperal infection

American Journal of Obstetrics and Gynecology

Volumn 177, Issue 4, 1997, Pages 786-792

  Mitra, A G ^a   Whitten, M K ^a   Laurent, S L ^a   Anderson, W E ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Chorioamnionitis; Endometritis; Once daily gentamicin

Indexed keywords

ANTIBIOTIC AGENT; CEFOXITIN; CIPROFLOXACIN; CLINDAMYCIN; CREATININE; DOXYCYCLINE; GENTAMICIN; SULTAMICILLIN; TIMENTIN;

ADULT; ARTICLE; CHORIOAMNIONITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG COST; ENDOMETRITIS; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; NEPHROTOXICITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUERPERAL INFECTION; RANDOMIZED CONTROLLED TRIAL;

EID: 0030719866     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(97)70269-2     Document Type: Article

References (20)

1. JM Prins HR Buller EJ Kuijper RA Tange P. Speelman Once versus thrice daily gentamicin in patients with serious infections Lancet 341 1993 335 339
2. L Nordstrom H Ringberg S Cronberg O Tjernstrom M. Walder Does administration of an aminoglycoside in a single daily dose affect its efficacy and toxicity? J Antimicrob Chemother 25 1990 159 173
3. AM Galloe N Graudal HR Christensen JP. Kampmann Aminoglycosides: single or multiple daily dosing? a meta-analysis on efficacy and safety Eur J Clin Pharmacol 48 1995 39 43
4. AW. Sturm Netilmicin in the treatment of gram-negative bacteremia: single daily versus multiple daily dosage J Infect Dis 159 1989 931 937
5. LF Hollender J Bahnin N Demanzini WY Lau ST Fan K Hermansyur A multicentric study of netilmicin once daily versus thrice daily in patients with appendicitis and other intra-abdominal infections Antimicrob Agents Chemother 23 1989 773 783
6. DN. Gilbert Once-daily aminoglycoside therapy Antimicrob Agents Chemother 35 1991 399 405
7. GD Priore M Jackson-Stone EK Shim J Garfinkel MA Eichmann MC. Frederiksen A comparison of once-daily and 8-hour gentamicin dosing in the treatment of postpartum endometritis Obstet Gynecol 87 1996 994 1000
8. AW Chow PJ. Jewesson Pharmacokinetics and safety of antimicrobial agents during pregnancy Rev Infect Dis 7 1985 287 313
9. ST Fan WY Lau CH Teoh-Chan KF Lau EH. Mauracher Once daily administration of netilmicin compared with thrice daily, both in combination with metronidazole, in gangrenous and perforated appendicitis J Antimicrob Chemother 22 1988 69 74
10. R Maller B Isaksson K Nilsson L. Soren A study of amikacin given once versus twice daily in serious infection J Antimicrob Chemother 22 1988 75 79
11. JJ Mordenti R Quintiliani CH. Nightingale Combination antibiotic therapy: comparison of constant infusion and intermittent bolus during an experimental animal model J Antimicrob Chemother 15 1985 313 321
12. SH Powell W Thompson MA Luthe RC Stern DA Grossniklous D Bloxhem Antibiotic dosing: efficacy or toxicity in animal and clinical studies of gentamicin, netilmicin, and tobramycin J Infect Dis 194 1983 918 932
13. GA Verpooten RA Giuliano L Verbist G Eestermans ME. DeBroe Once daily dosing decreases renal accumulation of gentamicin and netilmicin Clin Pharmacol Ther 45 1989 22 27
14. BS Vogelman WA. Craig Postantibiotic effects J Antimicrob Chemother 15 1985 37 46
15. BS Vogelman S Gudmundson J Turnridge J Leggett WA. Craig In vivo postantibiotic effect in thigh infection in neutropenic mice J Infect Dis 157 1988 287 295
16. L Nordstrom SA. Lerner Single daily dose therapy with aminoglycosides J Hosp Infect 18 1991 117 129
17. H Mattie WA Craig JL. Pechere Determinants of efficacy and toxicity of aminoglycosides J Antimicrob Chemother 24 1989 281 289
18. ME. Levison New dosing regimens for aminoglycoside antibiotics Ann Intern Med 117 1992 693 694
19. SG McNeeley R Beitel M Lee C Moise PV. Dilts Delayed gentamicin elimination in patients with severe preeclampsia Am J Obstet Gynecol 153 1985 793 796
20. JA Hanley A. Lippman-Hand If nothing goes wrong, is everything all right? Interpreting zero numerators JAMA 249 1983 1743 1745