Sp1-mediated transactivation of LamC1 promoter and coordinated expression of laminim-γ1 and Sp1 in human hepatocellular carcinomas

American Journal of Pathology

Volumn 151, Issue 6, 1997, Pages 1663-1672

  Liétard, Jocelyne ^a   Musso, Orlando ^a   Théret, Nathalie ^a   L'Helgoualc'h, Annie ^a   Campion, Jean Pierre ^a   Yamada, Yoshihiko ^b   Clément, Bruno ^a,c  

^a UNIVERSITÉ DE RENNES 1   (France)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CANCER INVASION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; STROMA CELL; TRANSACTIVATION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CHROMOSOME MAPPING; DNA PRIMERS; DNA, NEOPLASM; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU HYBRIDIZATION; LAMININ; LIVER; LIVER NEOPLASMS; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; SP4 TRANSCRIPTION FACTOR; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0030717596     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Burgeson RE, Chiquet M, Deutzmann R, Ekblom P, Engel J, Kleinman HK, Martin GR, Meneguzzi M, Paulsson M, Sanes J, Timpl R, Tryggvason K, Yamada Y, Yurchenco PD: A new nomenclature for the laminins. Matrix Biol 1994, 14:209-211
2. Engvall E, Earwicker D, Haaparanta T, Ruoslahti E, James JR: Distribution and isolation of four laminin variants: tissue restricted distribution of heterotrimers assembled from five different subunits. Cell Regul 1990, 1:731-740
3. Martin GR, Timpl R: Laminin and other basement membrane components. Annu Rev Cell Biol 1987, 3:57-85
4. Caron JM: Induction of albumin gene transcription in hepatocytes by extracellular matrix proteins. Mol Cell Biol 1990, 3:1239-1243
5. Rescan PY, Clément B, Yamada Y, Segui-Real B, Baffet G, Guguen-Guillouzo C, Guillouzo A: Differential expression of laminin chains and receptor (LBP-32) in fetal and neoplastic hepatocytes compared to normal adult hepatocytes in vivo and in culture. Am J Pathol 1990, 137:701-709
6. Wewer UM, Engvall E, Paulsson M, Yamada Y, Albrechtsen R: Laminin A, B1, B2, S, and M subunits in the postnatal rat liver development and after partial hepatectomy. Lab Invest 1992, 66:378-389
7. Clément B, Rescan PY, Baffet G, Loréal O, Lhery D, Campion JP, Guillouzo A: Hepatocytes may produce laminin in fibrotic liver and in primary culture. Hepatology 1988, 8:794-803
8. Loréal O, Levavasseur F, Rescan PY, Yamada Y, Guillouzo A, Clément B: Differential expression of laminin chains in hepatic lipocytes. FEBS Lett 1991, 290:9-12
9. Maher JJ, McGuire RF: Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest 1990, 86:1641-1648
10. Rescan PY, Clément B, Yamada Y, Glaise D, Segui-Real B, Guguen-Guillouzo C, Guillouzo A: Expression of laminin and its receptor LBP-32 in human and rat hepatoma cells. Hepatology 1991, 13:289-296
11. Levavasseur F, Liétard J, Ogawa K, Théret N, Burbelo PD, Yamada Y, Guillouzo A, Clément B: Expression of laminin-γ1 in cultured hepatocytes involves repeated CTC and GC elements in the LAMC1 promoter. Biochem J 1996, 313:745-752
12. Kadonaga JT, Carner KC, Masiarz FR, Tjian R: Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 1987, 51:1079-1090
13. Briggs MR, Kadonaga JT, Bell SP, Tjian R: Purification and biochemical characterization of the promoter-specific transcription factor Sp1. Science 1986, 234:46-52
14. Lu J, Lee W, Jiang C, Keller EB: Start site selection by Sp1 in the TATA-less human Ha-ras promoter. J Biol Chem 1994, 269:5391-5402
15. DesJardins E, Hay N: Repeated CT elements bound by zinc finger proteins control the absolute and relative activities of the two principal human c-myc promoters. Mol Cell Biol 1993, 13:5710-5724
16. Kumar AP, Mar PK, Zhao B, Montgomery ML, Kang DC, Butler AP: Regulation of rat ornithine decarboxylase promoter activity by binding of transcription factor Sp1. J Biol Chem 1995, 270:4341-4348
17. Dusing MR, Wiginton DA: Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter. Nucleic Acids Res 1994, 22:669-677
18. Chen X, Azizkhan JC, Lee DC: The binding of transcription factor Sp1 to multiple sites is required for maximal expression from the rat transforming growth factor α promoter. Oncogene 1992, 7:1805-1815
19. Fazio MJ, O'Leary J, Kahari VM, Chen YQ, Saitta B, Uitto, J: Human nidogen gene: structural and functional characterization of the 5′-flanking region. J Invest Dermatol 1991, 97:281-285
20. Cohen IR, Grässel S, Murdoch AD, lozzo RV: Structural characterization of the complete human perlecan gene and its promoter. Proc Natl Acad Sci USA 1993, 90:10404-10408
21. Schmidt C, Fisher G, Kadner H, Genersch E, Kühn K, Pöschl E: Differential effects of DNA-binding proteins on bidirectional transcription on the common promoter region of human collagen type IV genes COL4A2. Biochem Biophys Acta 1993, 1174:1-10
22. Burbelo PD, Martin GR, Yamada Y: α1 (IV) and α2 (IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer. Proc Natl Acad Sci USA 1988, 85:9679-9682
23. Heikkilä P, Soininen R, Tryggvason K: Directional regulatory activity of cis-acting elements in the bidirectional α1(IV) and α2(IV) collagen gene promoter. J Biol Chem 1993, 268:24677-24682
24. Tamaki T, Ohnishi K, Hartl C, LeRoy EC, Trojanowska M: Characterization of a GC-rich region containing Sp1 binding site(s) as a constitutive responsive element of the α2 (I) collagen gene in human fibroblasts. J Biol Chem 1995, 270:4299-4304
25. Nehls MC, Rippe RA, Veloz L, Brenner DA: Transcription factors nuclear factor I and Sp1 interact with the murine collagen α1 (I) promoter. Mol Cell Biol 1991, 11:4065-4073
26. Nakamura T, Nakajima T, Tsunoda S, Nakada S, Oda K, Tsurui H, Wada A: Induction of E1A-responsive negative factors for transcription of the fibronectin gene in adenovirus E1-transformed rat cells. J Virol 1992, 66:6436-6450
27. Weiss MC, Sparlnes RS, Bertolotti R: Expression of differentiated functions in hepatoma cell hybrids: extension and reexpression of liver-specific enzymes in rat hepatoma-Chinese hamster fibroblast hybrids. Somat Cell Genet 1975, 1:27-40
28. Guguen-Guillouzo C, Guillouzo A (Eds): Methods for Preparation of Adult and Fetal Hepatocytes in Isolated and Cultured Hepatocytes: Les Editions INSERM. Paris, John Libbey, 1986, pp 1-12
29. Ogawa K, Burbelo PD, Sasaki M, Yamada Y: The laminin B2 promoter contains unique repeat sequences and is active in transient transfection. J Biol Chem 1988, 263:8384-8389
30. Courey AJ, Tjian R: Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 1988, 55:887-898
31. Bossard P, Parsa R, Decaux JF, Iynedjian P, Girard J: Glucose administration induces the premature expression of liver glucokinase gene in newborn rats. Eur J Biochem 1993, 215:883-892
32. Cereghini S, Blumenfeld M, Yaniv M: A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells. Genes Dev 1988, 2:957-974
33. Gorman CM, Moffat LF, Howard BH: Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 1982, 2:1044-1051
34. Chirgwin JM, Przybyla AE, McDonald RJ, Rutter WJ: Isolation of biologically active ribonucleic acid from sources enriched in ribonucleases. Biochemistry 1979, 18:5294-5299
35. Chan YL, Gutell R, Noller HF, Wool IG: The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid. J Biol Chem 1984, 259:224-230
36. Milani S, Herbst H, Schuppan D, Grappone C, Pellegrini G, Pinzani M, Casini A, Calabro A, Ciancio G, Stefanini F, Burroughs AK, Surrenti C: Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am J Pathol 1994, 144:528-537
37. Musso O, Théret N, Campion JP, Turlin B, Milani S, Grappone C, Clément B: In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis. J Hepatol 1997, 26:593-605
38. Svaren J, Hörz W: Histones, nucleosomes, and transcription. Curr Opin Genet Dev 1993, 3:219-225
39. Etienne PL, Baffet G, Desvergne M, Boisnard-Rissel M, Glaise D, Guguen-Guillouzo C: Transient expression of c-fos and constant expression of c-myc in freshly isolated and cultured normal adult rat hepatocytes. Oncogene Res 1988, 3:255-262
40. Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C: Growth factor dependence of progression G1 and S phases of adult rat hepatocytes in vitro: evidence of a mitogen restriction point in mid-late G1. J Biol Chem 1996, 271:11484-11492
41. Legget RW, Armstrong SA, Barry D, Mueller CR: Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver, J Biol Chem 1995, 270:25879-25884
42. Majello B, Luca PD, Suske G, Lania L: Differential transcriptional regulation of c-myc promoter through the same DNA binding sites targeted by Sp1-like proteins. Oncogene 1995, 10:1841-1848
43. Udvadia AJ, Rogers KT, Higgins PD, Murata Y, Martin KH, Humphrey PA, Horowitz JM: Sp1 binds promoter elements regulated by the RB protein, and Sp1-mediated transcription is stimulated by RB coexpression. Proc Natl Acad Sci USA 1993, 90:3265-3269
44. Geiser AG, Busam KJ, Kim SJ, Lafyatis R, O'Reilly MA, Roberts AB, Sporn MB: Regulation of the transforming growth factor-β1 and -β3 promoters by transcription factor Sp1. Gene 1993, 129:223-228
45. Kim SJ, Onwuta US, Lee YI, Li R, Botchan MR, Robbins PD: The retinoblastoma gene product regulates Sp1-mediated transcription. Mol Cell Biol 1992, 12:2455-2463
46. Perkins KK, Dailey GM, Tjian R: Novel Jun and Fos related proteins in Drosophila are functionally homologous to enhancer factor AP-1. EMBO J 1988, 7:4265-4273
47. Santoro C, Mermod N, Andrews PC, Tjian R: A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature 1988, 334:218-224
48. Pyre JJ, Moberg KH, Hall DJ: Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter. Biochemistry 1992, 31:4102-4110
49. Genersch E, Eckerskorn C, Lottspeich F, Herzog C, Kühn K, Pöschl E: Purification of the sequence-specific transcription factor CTCBF involved in the control of human collagen IV genes: subunits with homology to Ku antigen. EMBO J 1995, 14:791-800
50. Kolluri R, Torrey TA, Kinburgh AJ: A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif. Nucleic Acids Res 1992, 20:111-116
51. Wewer UM, Albrechtsen R: Carcinoma-associated perisinusoidal laminin may signal tumour cell metastasis to the liver. Virchows Arch 1992, 421:87-93
52. Rippe RA, Almounajed G, Brenner DA: Sp1 binding activity increases in activated Ito cells. Hepatology 1995, 22:241-251
53. Rana B, Mischoulon D, Xie Y, Bucher NLR, Farmer S: Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: reciprocal expression of C/EBPα and immediate-early growth response transcription factors. Mol Cell Biol 1994, 14:585-586