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Volumn 64, Issue 9, 1997, Pages 1227-1235

Gene targeting: Techniques and applications to transplantation

Author keywords

[No Author keywords available]

Indexed keywords

AUTOTRANSPLANTATION; GENE FUNCTION; GENE MUTATION; GENE TARGETING; GRAFT REJECTION; MAMMAL CELL; PHENOTYPE; PRIORITY JOURNAL; REVIEW; XENOGRAFT;

EID: 0030716876     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199711150-00001     Document Type: Review
Times cited : (6)

References (79)
  • 2
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • Capecchi MR. Altering the genome by homologous recombination. Science 1989; 244: 1288.
    • (1989) Science , vol.244 , pp. 1288
    • Capecchi, M.R.1
  • 5
    • 0001837422 scopus 로고    scopus 로고
    • Gene targeting as an approach to gene therapy
    • Lemoine NR, Cooper DN, eds. Oxford: BIOS Scientific Publishers
    • Porter ACG. Gene targeting as an approach to gene therapy. In: Lemoine NR, Cooper DN, eds. Gene therapy. Oxford: BIOS Scientific Publishers, 1996: 169.
    • (1996) Gene Therapy , pp. 169
    • Porter, A.C.G.1
  • 6
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987; 51: 503.
    • (1987) Cell , vol.51 , pp. 503
    • Thomas, K.R.1    Capecchi, M.R.2
  • 7
    • 0025073480 scopus 로고
    • Homologous recombination in hybridoma cells: Dependence on time and fragment length
    • Shulman MJ, Nissen L, Collins C. Homologous recombination in hybridoma cells: dependence on time and fragment length. Mol Cell Biol 1990; 10: 4466.
    • (1990) Mol Cell Biol , vol.10 , pp. 4466
    • Shulman, M.J.1    Nissen, L.2    Collins, C.3
  • 8
    • 0025195027 scopus 로고
    • Replacement recombinant events targeted at immunoglobulin heavy chain DNA sequences in mouse myeloma cells
    • Smith AJ, Kalogerakis B. Replacement recombinant events targeted at immunoglobulin heavy chain DNA sequences in mouse myeloma cells. J Mol Biol 1990; 213: 415.
    • (1990) J Mol Biol , vol.213 , pp. 415
    • Smith, A.J.1    Kalogerakis, B.2
  • 9
    • 0026753186 scopus 로고
    • Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus
    • Deng C, Capecchi MR. Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol Cell Biol 1992; 12: 3365.
    • (1992) Mol Cell Biol , vol.12 , pp. 3365
    • Deng, C.1    Capecchi, M.R.2
  • 10
    • 0026771287 scopus 로고
    • Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs
    • te Riele H, Maandag ER, Berns A. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc Natl Acad Sci USA 1992; 89: 5128.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5128
    • Te Riele, H.1    Maandag, E.R.2    Berns, A.3
  • 11
    • 0026737822 scopus 로고
    • Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors
    • van Deursen J, Wieringa B. Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors. Nucleic Acids Res 1992; 20: 3815.
    • (1992) Nucleic Acids Res , vol.20 , pp. 3815
    • Van Deursen, J.1    Wieringa, B.2
  • 12
    • 0024296027 scopus 로고
    • Disruption of the protooncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes
    • Mansour SL, Thomas KR, Capecchi MR. Disruption of the protooncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature 1988; 336: 348.
    • (1988) Nature , vol.336 , pp. 348
    • Mansour, S.L.1    Thomas, K.R.2    Capecchi, M.R.3
  • 13
    • 0024118441 scopus 로고
    • Homologous integration in mammalian cells without target gene selection
    • Jasin M, Berg P. Homologous integration in mammalian cells without target gene selection. Genes Dev 1988; 2: 1353.
    • (1988) Genes Dev , vol.2 , pp. 1353
    • Jasin, M.1    Berg, P.2
  • 14
    • 0024549494 scopus 로고
    • Selection for precise chromosomal targeting of a dominant marker by homologous recombination
    • Dorin JR, Inglis JD, Porteous DJ. Selection for precise chromosomal targeting of a dominant marker by homologous recombination. Science 1989; 243: 1357.
    • (1989) Science , vol.243 , pp. 1357
    • Dorin, J.R.1    Inglis, J.D.2    Porteous, D.J.3
  • 15
    • 0038658494 scopus 로고
    • Positive genetic selection for gene disruption in mammalian cells by homologous recombination
    • Sedivy JM, Sharp PA. Positive genetic selection for gene disruption in mammalian cells by homologous recombination. Proc Natl Acad Sci USA 1989; 86: 227.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 227
    • Sedivy, J.M.1    Sharp, P.A.2
  • 16
    • 0025264733 scopus 로고
    • High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination
    • Charron J, Malynn BA, Robertson EJ, Goff SP, Alt FW. High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination. Mol Cell Biol 1990; 10: 1799.
    • (1990) Mol Cell Biol , vol.10 , pp. 1799
    • Charron, J.1    Malynn, B.A.2    Robertson, E.J.3    Goff, S.P.4    Alt, F.W.5
  • 17
    • 0025866786 scopus 로고
    • Targeted disruption of a human interferon-inducible gene detected by secretion of human growth hormone
    • Itzhaki JE, Porter AC. Targeted disruption of a human interferon-inducible gene detected by secretion of human growth hormone. Nucleic Acids Res 1991; 19: 3835.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3835
    • Itzhaki, J.E.1    Porter, A.C.2
  • 18
    • 0028279829 scopus 로고
    • Dicistronic targeting constructs: Reporters and modifiers of mammalian gene expression
    • Mountford P, Zevnik B, Duwel A, et al. Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci USA 1994; 91: 4303.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4303
    • Mountford, P.1    Zevnik, B.2    Duwel, A.3
  • 19
    • 0021646210 scopus 로고
    • Homologous recombination between defective neo genes in mouse 3T6 cells
    • Smith AJ, Berg P. Homologous recombination between defective neo genes in mouse 3T6 cells. Cold Spring Harbor Symp Quant Biol 1984; 49: 171.
    • (1984) Cold Spring Harbor Symp Quant Biol , vol.49 , pp. 171
    • Smith, A.J.1    Berg, P.2
  • 20
    • 0021911240 scopus 로고
    • Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences
    • Lin FL, Sperle K, Sternberg N. Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences. Proc Natl Acad Sci USA 1985; 82: 1391.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1391
    • Lin, F.L.1    Sperle, K.2    Sternberg, N.3
  • 21
    • 0029328313 scopus 로고
    • Targeting the mouse genome: A compendium of knockouts (part II)
    • Brandon EP, Idzerda RL, McKnight GS. Targeting the mouse genome: a compendium of knockouts (part II). Curr Biol 1995; 5: 758.
    • (1995) Curr Biol , vol.5 , pp. 758
    • Brandon, E.P.1    Idzerda, R.L.2    McKnight, G.S.3
  • 22
    • 0029347193 scopus 로고
    • Targeting the mouse genome: A compendium of knockouts (part III)
    • Brandon EP, Idzerda RL, McKnight GS. Targeting the mouse genome: a compendium of knockouts (part III). Curr Biol 1995; 5: 873.
    • (1995) Curr Biol , vol.5 , pp. 873
    • Brandon, E.P.1    Idzerda, R.L.2    McKnight, G.S.3
  • 23
    • 0029163860 scopus 로고
    • Knockouts. Targeting the mouse genome: A compendium of knockouts (part I)
    • Brandon EP, Idzerda RL, McKnight GS. Knockouts. Targeting the mouse genome: a compendium of knockouts (part I). Curr Biol 1995; 5: 625.
    • (1995) Curr Biol , vol.5 , pp. 625
    • Brandon, E.P.1    Idzerda, R.L.2    McKnight, G.S.3
  • 25
    • 0027143957 scopus 로고
    • Gene targeting in human somatic cells: Complete inactivation of an interferon-inducible gene
    • Porter AC, Itzhaki JE. Gene targeting in human somatic cells: complete inactivation of an interferon-inducible gene. Eur J Biochem 1993; 218: 273.
    • (1993) Eur J Biochem , vol.218 , pp. 273
    • Porter, A.C.1    Itzhaki, J.E.2
  • 26
    • 0028849274 scopus 로고
    • p21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman T, Kinzler KW, Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 1995; 55: 5187.
    • (1995) Cancer Res , vol.55 , pp. 5187
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 27
    • 0029993449 scopus 로고    scopus 로고
    • Know your neighbours: Three phenotypes in null mutants of the myogenic bHLH gene MRF4
    • Olson EN, Arnold H-H, Rigby PWJ, Wold BJ. Know your neighbours: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell 1996; 85: 1.
    • (1996) Cell , vol.85 , pp. 1
    • Olson, E.N.1    Arnold, H.-H.2    Rigby, P.W.J.3    Wold, B.J.4
  • 28
    • 0027316203 scopus 로고
    • Site-directed point mutations in embryonic stem cells: A gene-targeting tag- and-exchange strategy
    • Askew GR, Doetschman T, Lingrel JB. Site-directed point mutations in embryonic stem cells: a gene-targeting tag- and-exchange strategy. Mol Cell Biol 1993; 13: 4115.
    • (1993) Mol Cell Biol , vol.13 , pp. 4115
    • Askew, G.R.1    Doetschman, T.2    Lingrel, J.B.3
  • 29
    • 0026100231 scopus 로고
    • Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells
    • Valancius V, Smithies O. Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells. Mol Cell Biol 1991; 11: 1402.
    • (1991) Mol Cell Biol , vol.11 , pp. 1402
    • Valancius, V.1    Smithies, O.2
  • 30
    • 0026429190 scopus 로고
    • Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
    • Hasty P, Ramirez Solis R, Krumlauf R, Bradley A. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature 1991; 350: 243.
    • (1991) Nature , vol.350 , pp. 243
    • Hasty, P.1    Ramirez Solis, R.2    Krumlauf, R.3    Bradley, A.4
  • 31
    • 0027264139 scopus 로고
    • Genomic targeting with purified Cre recombinase
    • Baubonis W, Sauer B. Genomic targeting with purified Cre recombinase. Nucleic Acids Res 1993; 21: 2025.
    • (1993) Nucleic Acids Res , vol.21 , pp. 2025
    • Baubonis, W.1    Sauer, B.2
  • 32
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994; 265: 103.
    • (1994) Science , vol.265 , pp. 103
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 34
    • 0027322465 scopus 로고
    • Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8
    • Schilham MW, Fung-Leung W-P, Rahemtulla A, et al. Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8. Eur J Immunol 1993; 23: 1299.
    • (1993) Eur J Immunol , vol.23 , pp. 1299
    • Schilham, M.W.1    Fung-Leung, W.-P.2    Rahemtulla, A.3
  • 35
  • 36
    • 0031037222 scopus 로고    scopus 로고
    • Construction by gene targeting in human cells of a "conditional" CDC2 mutant that rereplicates its DNA
    • Itzhaki JE, Gilbert CS, Porter ACG. Construction by gene targeting in human cells of a "conditional" CDC2 mutant that rereplicates its DNA. Nature Genet 1997; 15: 258.
    • (1997) Nature Genet , vol.15 , pp. 258
    • Itzhaki, J.E.1    Gilbert, C.S.2    Porter, A.C.G.3
  • 41
    • 0027538467 scopus 로고
    • The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice
    • Auchincloss H, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proc Natl Acad Sci USA 1993; 90: 3373.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3373
    • Auchincloss, H.1    Lee, R.2    Shea, S.3    Markowitz, J.S.4    Grusby, M.J.5    Glimcher, L.H.6
  • 42
    • 0027443486 scopus 로고
    • Graft rejection by T cells not restricted by conventional major histocompatibility complex molecules
    • Dierich A, Chan SH, Benoist C, Mathis D. Graft rejection by T cells not restricted by conventional major histocompatibility complex molecules. Eur J Immunol 1993; 23: 2725.
    • (1993) Eur J Immunol , vol.23 , pp. 2725
    • Dierich, A.1    Chan, S.H.2    Benoist, C.3    Mathis, D.4
  • 43
    • 0027470127 scopus 로고
    • Use of donor beta 2-microglobulin-deficient transgenic mouse liver cells for isografts, allografts and xenografts
    • Li X, Faustman D. Use of donor beta 2-microglobulin-deficient transgenic mouse liver cells for isografts, allografts and xenografts. Transplantation 1993; 55: 940.
    • (1993) Transplantation , vol.55 , pp. 940
    • Li, X.1    Faustman, D.2
  • 44
    • 0028799549 scopus 로고
    • Marked prolongation of incompatible class I deficient heart allografts: Paradoxical effects between primarily and secondarily vascularized allografts
    • Henretta J, Araneda D, Pittman K, Thomas F. Marked prolongation of incompatible class I deficient heart allografts: paradoxical effects between primarily and secondarily vascularized allografts. Transplant Proc 1995; 27: 1303.
    • (1995) Transplant Proc , vol.27 , pp. 1303
    • Henretta, J.1    Araneda, D.2    Pittman, K.3    Thomas, F.4
  • 45
    • 0028950606 scopus 로고
    • Rejection of kidney allografts by MHC class I-deficient mice
    • Mannon RB, Nataraj C, Kotzin BL, et al. Rejection of kidney allografts by MHC class I-deficient mice. Transplantation 1995; 59: 746.
    • (1995) Transplantation , vol.59 , pp. 746
    • Mannon, R.B.1    Nataraj, C.2    Kotzin, B.L.3
  • 46
    • 0027051380 scopus 로고
    • Indefinite survival of MHC class I-deficient murine pancreatic islet allografts
    • Markmann JF, Bassiri H, Desai NM, et al. Indefinite survival of MHC class I-deficient murine pancreatic islet allografts. Transplantation 1992; 54: 1085.
    • (1992) Transplantation , vol.54 , pp. 1085
    • Markmann, J.F.1    Bassiri, H.2    Desai, N.M.3
  • 47
    • 0028815345 scopus 로고
    • Survival of MHC-deficient mouse heterotopic cardiac allografts
    • Campos L, Naji A, Deli BC, et al. Survival of MHC-deficient mouse heterotopic cardiac allografts. Transplantation 1995; 59: 187.
    • (1995) Transplantation , vol.59 , pp. 187
    • Campos, L.1    Naji, A.2    Deli, B.C.3
  • 49
    • 0028031970 scopus 로고
    • Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo
    • Lee RS, Grusby MJ, Glimcher LH, Winn HJ, Auchincloss H Jr. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J Exp Med 1994; 179: 865.
    • (1994) J Exp Med , vol.179 , pp. 865
    • Lee, R.S.1    Grusby, M.J.2    Glimcher, L.H.3    Winn, H.J.4    Auchincloss H., Jr.5
  • 51
    • 0028221776 scopus 로고
    • + cytotoxic T lymphocytes in beta 2-microglobulin-negative, MHC class 1-deficient mice in response to immunization with tumor cells
    • + cytotoxic T lymphocytes in beta 2-microglobulin-negative, MHC class 1-deficient mice in response to immunization with tumor cells. J Immunol 1994; 1994; 152.
    • (1994) J Immunol
    • Apasov, S.G.1    Sitkovsky, M.V.2
  • 52
    • 0343344266 scopus 로고
    • + cytotoxic T lymphocytes in beta 2-microglobulin-negative, MHC class 1-deficient mice in response to immunization with tumor cells. J Immunol 1994; 1994; 152.
    • (1994) J Immunol , pp. 152
  • 53
    • 0029888609 scopus 로고    scopus 로고
    • -/- mice are sufficient to mediate rejection of MHC class II or class I disparate skin grafts
    • -/- mice are sufficient to mediate rejection of MHC class II or class I disparate skin grafts. J Immunol 1996; 156: 41114.
    • (1996) J Immunol , vol.156 , pp. 41114
    • Dalloul, A.H.1    Chmouzis, E.2    Ngo, K.3    Fung-Leung, W.-P.4
  • 54
    • 0030025604 scopus 로고    scopus 로고
    • CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice
    • Dalloul AH, Ngo K, Fung-Leung W-P. CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice. Bur J Immunol 1996; 26: 213.
    • (1996) Bur J Immunol , vol.26 , pp. 213
    • Dalloul, A.H.1    Ngo, K.2    Fung-Leung, W.-P.3
  • 56
    • 0030046658 scopus 로고    scopus 로고
    • Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection
    • Walsh CM, Hayashi F, Saffron DC, Ju S-T, Berke G, Clark WR. Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection. J Immunol 1996; 156: 1436.
    • (1996) J Immunol , vol.156 , pp. 1436
    • Walsh, C.M.1    Hayashi, F.2    Saffron, D.C.3    Ju, S.-T.4    Berke, G.5    Clark, W.R.6
  • 57
    • 0030458560 scopus 로고    scopus 로고
    • The role of the perform and Fas pathways of cytotoxicity in skin graft rejection
    • Selvaggi G, Ricordi C, Podack ER, Inverardi L. The role of the perform and Fas pathways of cytotoxicity in skin graft rejection. Transplantation 1996; 62: 1912.
    • (1996) Transplantation , vol.62 , pp. 1912
    • Selvaggi, G.1    Ricordi, C.2    Podack, E.R.3    Inverardi, L.4
  • 58
    • 0028916025 scopus 로고
    • Acute rejection of vascular heart allografts by perforin-deficient mice
    • Schulz M, Schuurman H-J, Joergensen J, et al. Acute rejection of vascular heart allografts by perforin-deficient mice. Eur J Immunol 1995; 25: 474.
    • (1995) Eur J Immunol , vol.25 , pp. 474
    • Schulz, M.1    Schuurman, H.-J.2    Joergensen, J.3
  • 59
    • 0027257221 scopus 로고
    • Gene targeting yields a CD18-mutant mouse for study of inflammation
    • Wilson RW, Ballantyne CM, Smith CW, et al. Gene targeting yields a CD18-mutant mouse for study of inflammation. J Immunol 1993; 151: 1571.
    • (1993) J Immunol , vol.151 , pp. 1571
    • Wilson, R.W.1    Ballantyne, C.M.2    Smith, C.W.3
  • 60
    • 0028876520 scopus 로고
    • Cytokines and transplantation: Th1/Th2 regulation of the immune response to solid organ transplants in the adult
    • Dallman MJ. Cytokines and transplantation: Th1/Th2 regulation of the immune response to solid organ transplants in the adult. Curr Opin Immunol 1995; 7: 632.
    • (1995) Curr Opin Immunol , vol.7 , pp. 632
    • Dallman, M.J.1
  • 64
    • 0029886947 scopus 로고    scopus 로고
    • Prolonged islet allograft acceptance in the absence of interleukin 4 expression
    • Nickerson P, Zheng XX, Steiger J, et al. Prolonged islet allograft acceptance in the absence of interleukin 4 expression. Transplant Immunol 1996; 4: 81.
    • (1996) Transplant Immunol , vol.4 , pp. 81
    • Nickerson, P.1    Zheng, X.X.2    Steiger, J.3
  • 65
    • 0031091771 scopus 로고    scopus 로고
    • Blocking the CD28-B7 T cell costimulation pathway induces long term cardiac allograft acceptance in the absence of IL-4
    • Lakkis FG, Konieczny BT, Saleem S, et al. Blocking the CD28-B7 T cell costimulation pathway induces long term cardiac allograft acceptance in the absence of IL-4. J Immunol 1997; 158: 2443.
    • (1997) J Immunol , vol.158 , pp. 2443
    • Lakkis, F.G.1    Konieczny, B.T.2    Saleem, S.3
  • 66
    • 0027380542 scopus 로고
    • Xenografting: Probability, possibility or pipe dream?
    • White D, Wallwork J. Xenografting: probability, possibility or pipe dream? Lancet 1993; 342: 879.
    • (1993) Lancet , vol.342 , pp. 879
    • White, D.1    Wallwork, J.2
  • 67
    • 0028073428 scopus 로고
    • A perspective on xenograft rejection and accommodation
    • Platt JL. A perspective on xenograft rejection and accommodation. Immunol Rev 1994; 141: 127.
    • (1994) Immunol Rev , vol.141 , pp. 127
    • Platt, J.L.1
  • 68
    • 0029618771 scopus 로고
    • Functional activity of the membrane-associated complement inhibitor CD59 in a pig-to-human in vitro model for hyperacute xenograft rejection
    • Heckl Ostreicher B, Binder R, Kirschfink M. Functional activity of the membrane-associated complement inhibitor CD59 in a pig-to-human in vitro model for hyperacute xenograft rejection. Clin Exp Immunol 1995; 102: 589.
    • (1995) Clin Exp Immunol , vol.102 , pp. 589
    • Heckl Ostreicher, B.1    Binder, R.2    Kirschfink, M.3
  • 69
    • 0343344263 scopus 로고    scopus 로고
    • The function of transgenic human DAF-expressing porcine livers during hemoperfusion with human blood
    • Pohlein C, Pascher A, Storck M, et al. The function of transgenic human DAF-expressing porcine livers during hemoperfusion with human blood. Transpl Int 1996; 9: 0934.
    • (1996) Transpl int , vol.9 , pp. 0934
    • Pohlein, C.1    Pascher, A.2    Storck, M.3
  • 70
    • 0031044215 scopus 로고    scopus 로고
    • Viable offspring derived from fetal and adult mammalian cells
    • Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH. Viable offspring derived from fetal and adult mammalian cells [see comments]. Nature 1997; 385: 810.
    • (1997) Nature , vol.385 , pp. 810
    • Wilmut, I.1    Schnieke, A.E.2    McWhir, J.3    Kind, A.J.4    Campbell, K.H.5
  • 71
    • 0029839492 scopus 로고    scopus 로고
    • Molecular barriers to xenotransplantation
    • Lawson JH, Platt JL. Molecular barriers to xenotransplantation. Transplantation 1996; 62: 303.
    • (1996) Transplantation , vol.62 , pp. 303
    • Lawson, J.H.1    Platt, J.L.2
  • 72
    • 9044248239 scopus 로고    scopus 로고
    • The alpha-1,3-galactosyltransferase knockout mouse: Implications for xeno-transplantation
    • Tearle RG, Tange MJ, Zannettino ZL, et al. The alpha-1,3-galactosyltransferase knockout mouse: implications for xeno-transplantation. Transplantation 1996; 61: 13.
    • (1996) Transplantation , vol.61 , pp. 13
    • Tearle, R.G.1    Tange, M.J.2    Zannettino, Z.L.3
  • 73
    • 0029869630 scopus 로고    scopus 로고
    • Alpha 1,3-galactosyltransferase-deficient mice produce naturally occurring cytotoxic anti-Gal antibodies
    • Thall AD, Murphy HS, Lowe JB. Alpha 1,3-galactosyltransferase-deficient mice produce naturally occurring cytotoxic anti-Gal antibodies. Transplant Proc 1996; 28: 556.
    • (1996) Transplant Proc , vol.28 , pp. 556
    • Thall, A.D.1    Murphy, H.S.2    Lowe, J.B.3
  • 74
    • 0028807727 scopus 로고
    • T lymphocyte-directed gene therapy for ADA-SCID: Initial trial results after 4 years
    • Blaese RM, Culver KW, Miller AD, et al. T lymphocyte-directed gene therapy for ADA-SCID: initial trial results after 4 years. Science 1995; 270: 475.
    • (1995) Science , vol.270 , pp. 475
    • Blaese, R.M.1    Culver, K.W.2    Miller, A.D.3
  • 77
    • 0025815689 scopus 로고
    • Prospects for homologous recombination in human gene therapy
    • Vega MA. Prospects for homologous recombination in human gene therapy. Hum Genet 1991; 87: 245.
    • (1991) Hum Genet , vol.87 , pp. 245
    • Vega, M.A.1
  • 78
    • 0028334223 scopus 로고
    • Gene targeting in normal somatic cells: Inactivation of the interferon-gamma receptor in myoblasts
    • Arbones ML, Austin HA, Capon DJ, Greenburg G. Gene targeting in normal somatic cells: inactivation of the interferon-gamma receptor in myoblasts. Nat Genet 1994; 6: 90.
    • (1994) Nat Genet , vol.6 , pp. 90
    • Arbones, M.L.1    Austin, H.A.2    Capon, D.J.3    Greenburg, G.4
  • 79
    • 0028824881 scopus 로고
    • Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin
    • Vilquin J-T, Wagner E, Kinoshita I, Roy R, Tremblay JP. Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin. J Cell Biol 1995; 131: 975.
    • (1995) J Cell Biol , vol.131 , pp. 975
    • Vilquin, J.-T.1    Wagner, E.2    Kinoshita, I.3    Roy, R.4    Tremblay, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.