메뉴 건너뛰기




Volumn 90, Issue 11, 1997, Pages 4394-4402

Thrombopoietin upregulates the promoter conformation of p53 in a proliferation-independent manner coincident with a decreased expression of Bax: Potential mechanisms for survival enhancing effects

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PROTEIN P53; THROMBOPOIETIN;

EID: 0030714669     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.11.4394     Document Type: Article
Times cited : (22)

References (60)
  • 1
    • 0026533515 scopus 로고
    • Programmed cell death (apoptosis) in hematopoiesis
    • Koury MJ: Programmed cell death (apoptosis) in hematopoiesis. Exp Hematol 20:391, 1992
    • (1992) Exp Hematol , vol.20 , pp. 391
    • Koury, M.J.1
  • 2
    • 0028873964 scopus 로고
    • Fas- and TNF-induced apoptosis is inhibited by the poxvirus crmA gene product
    • Tewari M, Dixit VM: Fas- and TNF-induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem 270:3255, 1995
    • (1995) J Biol Chem , vol.270 , pp. 3255
    • Tewari, M.1    Dixit, V.M.2
  • 3
    • 0025963456 scopus 로고
    • IL-3-dependent cells die by apoptosis on removal of their growth factor
    • Crompton T: IL-3-dependent cells die by apoptosis on removal of their growth factor. Growth Factors 4:109, 1991
    • (1991) Growth Factors , vol.4 , pp. 109
    • Crompton, T.1
  • 4
    • 0025163927 scopus 로고
    • Regulation of apoptosis in interleukin-3-dependent hematopoietic cells by interleukin-3 and calcium ionophores
    • Rodriguez-Tarduchy G, Collins M, Lopez-Rivas A: Regulation of apoptosis in interleukin-3-dependent hematopoietic cells by interleukin-3 and calcium ionophores. EMBO J 9:2997, 1990
    • (1990) EMBO J , vol.9 , pp. 2997
    • Rodriguez-Tarduchy, G.1    Collins, M.2    Lopez-Rivas, A.3
  • 5
    • 0025091773 scopus 로고
    • Haematopoietic colony stimulating factors promote cell survival by suppressing apoptosis
    • Williams GT, Smith CA, Spooner E, Dexter TM, Taylor DR: Haematopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76, 1990
    • (1990) Nature , vol.343 , pp. 76
    • Williams, G.T.1    Smith, C.A.2    Spooner, E.3    Dexter, T.M.4    Taylor, D.R.5
  • 7
    • 0028847937 scopus 로고
    • The combination of steel factor and GM-CSF blocks apoptosis induced by retinoic acid and upregulates AP-1 in a human growth factor-dependent cell line
    • Horie M, Broxmeyer HE: The combination of steel factor and GM-CSF blocks apoptosis induced by retinoic acid and upregulates AP-1 in a human growth factor-dependent cell line. Exp Hematol 23:168, 1995
    • (1995) Exp Hematol , vol.23 , pp. 168
    • Horie, M.1    Broxmeyer, H.E.2
  • 8
    • 0029894091 scopus 로고    scopus 로고
    • Thrombopoietin behaves as a survival factor and suppresses apoptosis in a human growth factor dependent cell line M07e
    • Ritchie A, Raj S, Broxmeyer HE: Thrombopoietin behaves as a survival factor and suppresses apoptosis in a human growth factor dependent cell line M07e. Stem Cells 14:330, 1996
    • (1996) Stem Cells , vol.14 , pp. 330
    • Ritchie, A.1    Raj, S.2    Broxmeyer, H.E.3
  • 9
    • 1842386795 scopus 로고
    • Oxford, UK, Oxford University Press
    • Williams GT: Apoptosis. Oxford, UK, Oxford University Press, 1991, p 69
    • (1991) Apoptosis , pp. 69
    • Williams, G.T.1
  • 10
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M: Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 352:345, 1991
    • (1991) Nature , vol.352 , pp. 345
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 12
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone LR, White R, Sprouse J, Livanous E, Jacks T, Tolsty TD: Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70:923, 1992
    • (1992) Cell , vol.70 , pp. 923
    • Livingstone, L.R.1    White, R.2    Sprouse, J.3    Livanous, E.4    Jacks, T.5    Tolsty, T.D.6
  • 15
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyahsita T, Reed JC: Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293, 1995
    • (1995) Cell , vol.80 , pp. 293
    • Miyahsita, T.1    Reed, J.C.2
  • 16
    • 0028266265 scopus 로고
    • Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells
    • Zhu Y-M, Bradbury DA, Russell NH: Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells. Br J Cancer 69:468, 1994
    • (1994) Br J Cancer , vol.69 , pp. 468
    • Zhu, Y.-M.1    Bradbury, D.A.2    Russell, N.H.3
  • 17
    • 0028294898 scopus 로고
    • Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb E, Haffner R, von Ruden T, Wagner EF, Oren M: Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J 13:1368, 1994
    • (1994) EMBO J , vol.13 , pp. 1368
    • Gottlieb, E.1    Haffner, R.2    Von Ruden, T.3    Wagner, E.F.4    Oren, M.5
  • 19
    • 0027536952 scopus 로고
    • Growth suppression of friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erylhropoietin
    • Johnson P, Chung S, Benchimol S: Growth suppression of friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erylhropoietin. Mol Cell Biol 13:1456, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 1456
    • Johnson, P.1    Chung, S.2    Benchimol, S.3
  • 20
    • 0028879323 scopus 로고
    • Regulation of p53-mediated apoptosis and cell cycle arrest by steel factor
    • Abrahamson JLA, Lee JM, Bernstein A: Regulation of p53-mediated apoptosis and cell cycle arrest by steel factor. Mol Cell Biol 15:6953, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 6953
    • Abrahamson, J.L.A.1    Lee, J.M.2    Bernstein, A.3
  • 21
    • 0021456846 scopus 로고
    • Monoclonal antibodies against simian virus 40 nuclear large T antigen: Epitope mapping papova virus cross-reaction and cell surface staining
    • Ball RK, Siegle B, Quellhorst S, Brander G, Braun DG: Monoclonal antibodies against simian virus 40 nuclear large T antigen: Epitope mapping papova virus cross-reaction and cell surface staining. EMBO J 3:1485, 1984
    • (1984) EMBO J , vol.3 , pp. 1485
    • Ball, R.K.1    Siegle, B.2    Quellhorst, S.3    Brander, G.4    Braun, D.G.5
  • 22
    • 0025221676 scopus 로고
    • Addition of fresh medium induces cell cycle and conformational changes in p53, a tumour suppressor protein
    • Milner J, Watson JV: Addition of fresh medium induces cell cycle and conformational changes in p53, a tumour suppressor protein. Oncogene 5:1683, 1990
    • (1990) Oncogene , vol.5 , pp. 1683
    • Milner, J.1    Watson, J.V.2
  • 23
    • 0025248598 scopus 로고
    • Activating mutations in p53 produce a common conformational effect: A monoclonal antibody specific for mutant form
    • Gannon JV, Greaves R, Iggo R, Lane DP: Activating mutations in p53 produce a common conformational effect: A monoclonal antibody specific for mutant form. EMBO J 9:1595, 1990
    • (1990) EMBO J , vol.9 , pp. 1595
    • Gannon, J.V.1    Greaves, R.2    Iggo, R.3    Lane, D.P.4
  • 24
    • 0025858155 scopus 로고
    • A conformational hypothesis for the suppressor and promoter functions of p53 in cell growth control and in cancer
    • Milner J: A conformational hypothesis for the suppressor and promoter functions of p53 in cell growth control and in cancer. Proc R Soc Lond 245:139, 1991
    • (1991) Proc R Soc Lond , vol.245 , pp. 139
    • Milner, J.1
  • 25
    • 0026767148 scopus 로고
    • Altered conformation of the p53 protein in myeloid leukemia cells and mitogen-stimulated normal blood cells
    • Zhang W, Hu G, Estey E, Hester J, Deisseroth A: Altered conformation of the p53 protein in myeloid leukemia cells and mitogen-stimulated normal blood cells. Oncogene 7:1645, 1992
    • (1992) Oncogene , vol.7 , pp. 1645
    • Zhang, W.1    Hu, G.2    Estey, E.3    Hester, J.4    Deisseroth, A.5
  • 26
    • 0027524810 scopus 로고
    • Expression of different conformations of p53 in the blast cells of acute myeloblastic leukaemia is related to in vitro growth characteristics
    • Zhu Y-M, Bradbury DA, Russell NH: Expression of different conformations of p53 in the blast cells of acute myeloblastic leukaemia is related to in vitro growth characteristics. Br J Cancer 68:851, 1993
    • (1993) Br J Cancer , vol.68 , pp. 851
    • Zhu, Y.-M.1    Bradbury, D.A.2    Russell, N.H.3
  • 29
    • 0027990778 scopus 로고
    • Induction of apoptosis by the mouse Nedd2 gene which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme
    • Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA: Induction of apoptosis by the mouse Nedd2 gene which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Develop 8:1613, 1994
    • (1994) Genes Develop , vol.8 , pp. 1613
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3    Copeland, N.G.4    Jenkins, N.A.5
  • 31
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homologue bax that accelerates apoptosis
    • Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homologue bax that accelerates apoptosis. Cell 74:609, 1993
    • (1993) Cell , vol.74 , pp. 609
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 33
    • 0029019765 scopus 로고
    • Thrombopoietin: Basic biology clinical promise
    • Kaushansky K: Thrombopoietin: Basic biology clinical promise. Int J Hematol 62:7, 1995
    • (1995) Int J Hematol , vol.62 , pp. 7
    • Kaushansky, K.1
  • 34
    • 0029089167 scopus 로고
    • Megakaryocytopoiesis: The state of the art
    • Gewirtz AM: Megakaryocytopoiesis: The state of the art. Thrombosis Haemostasis 74:204, 1995
    • (1995) Thrombosis Haemostasis , vol.74 , pp. 204
    • Gewirtz, A.M.1
  • 35
    • 0028909690 scopus 로고
    • Thrombopoietin (c-mpl ligand) acts synergystically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony formation and increase megakaryocyte ploidy in vitro
    • Broudy VC, Lin NL, Kaushansky K: Thrombopoietin (c-mpl ligand) acts synergystically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony formation and increase megakaryocyte ploidy in vitro. Blood 85:1719, 1995
    • (1995) Blood , vol.85 , pp. 1719
    • Broudy, V.C.1    Lin, N.L.2    Kaushansky, K.3
  • 39
    • 0025636017 scopus 로고
    • M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3
    • Avanzi G, Brizzi M, Giannotti J, Ciarletta A, Yang YC, Pegoraro L, Clark SC: M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3. J Cell Physiol 145:458, 1990
    • (1990) J Cell Physiol , vol.145 , pp. 458
    • Avanzi, G.1    Brizzi, M.2    Giannotti, J.3    Ciarletta, A.4    Yang, Y.C.5    Pegoraro, L.6    Clark, S.C.7
  • 40
    • 0026004856 scopus 로고
    • Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor dependent cell line M07e
    • Hendrie P, Miyazawa K, Yang YC, Langefeld CD, Broxmeyer HE: Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor dependent cell line M07e. Exp Hematol 19:1031, 1991
    • (1991) Exp Hematol , vol.19 , pp. 1031
    • Hendrie, P.1    Miyazawa, K.2    Yang, Y.C.3    Langefeld, C.D.4    Broxmeyer, H.E.5
  • 41
    • 0025938925 scopus 로고
    • Comparative analysis of signaling pathways between mast cell growth factor (c-kit) and granulocyte-macrophage colony stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of raf-1 GTPase-activating protein and mitogen-activated protein kinase
    • Miyazawa K, Hendrie P, Mantel C, Wood K, Ashman LK, Broxmeyer HE: Comparative analysis of signaling pathways between mast cell growth factor (c-kit) and granulocyte-macrophage colony stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of raf-1 GTPase-activating protein and mitogen-activated protein kinase. Exp Hematol 19:1110, 1991
    • (1991) Exp Hematol , vol.19 , pp. 1110
    • Miyazawa, K.1    Hendrie, P.2    Mantel, C.3    Wood, K.4    Ashman, L.K.5    Broxmeyer, H.E.6
  • 42
    • 0027371614 scopus 로고
    • The abnormal p53 proteins expressed in CML cell lines are non-functional
    • Bi S, Lanza F, Goldman JM: The abnormal p53 proteins expressed in CML cell lines are non-functional. Leukemia 7:1840, 1993
    • (1993) Leukemia , vol.7 , pp. 1840
    • Bi, S.1    Lanza, F.2    Goldman, J.M.3
  • 43
    • 0029072986 scopus 로고
    • Modulation of cell kinetics and cell cycle status by treating with CD34+ chronic myeloid leukaemia cells with p53 antisense phosphorothioate oligonucleotides
    • Lanza F, Bi S, Moretti S, Castoldi G, Goldman JM: Modulation of cell kinetics and cell cycle status by treating with CD34+ chronic myeloid leukaemia cells with p53 antisense phosphorothioate oligonucleotides. Br J Hematol 90:8, 1995
    • (1995) Br J Hematol , vol.90 , pp. 8
    • Lanza, F.1    Bi, S.2    Moretti, S.3    Castoldi, G.4    Goldman, J.M.5
  • 45
    • 0006120705 scopus 로고
    • Methods for the purification of thymus nuclei and their application to studies of nuclear protein synthesis
    • Allfrey VC, Littau VC, Mirsky AE: Methods for the purification of thymus nuclei and their application to studies of nuclear protein synthesis. J Cell Biol 21:213, 1964
    • (1964) J Cell Biol , vol.21 , pp. 213
    • Allfrey, V.C.1    Littau, V.C.2    Mirsky, A.E.3
  • 46
    • 0027361046 scopus 로고
    • Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
    • Hainaut P, Milner J: Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res 53:4469, 1993
    • (1993) Cancer Res , vol.53 , pp. 4469
    • Hainaut, P.1    Milner, J.2
  • 47
    • 0030006364 scopus 로고    scopus 로고
    • Steel factor induces serine phosphorylation of stat3 in human growth factor-dependent myeloid cell lines
    • Gotoh A, Takahira H, Mantel C, Litz-Jackson S, Boswell HS, Broxmeyer HE: Steel factor induces serine phosphorylation of stat3 in human growth factor-dependent myeloid cell lines. Blood 88:138, 1996
    • (1996) Blood , vol.88 , pp. 138
    • Gotoh, A.1    Takahira, H.2    Mantel, C.3    Litz-Jackson, S.4    Boswell, H.S.5    Broxmeyer, H.E.6
  • 49
    • 0019830333 scopus 로고
    • Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells
    • Oren M, Maltzman W, Levine AJ: Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol Cell Biol 1:101, 1981
    • (1981) Mol Cell Biol , vol.1 , pp. 101
    • Oren, M.1    Maltzman, W.2    Levine, A.J.3
  • 50
    • 0026649648 scopus 로고
    • The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ: The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237, 1992
    • (1992) Cell , vol.69 , pp. 1237
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 51
    • 0025975701 scopus 로고
    • Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport
    • Gannon JV, Lane DP: Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport. Nature 349:802, 1991
    • (1991) Nature , vol.349 , pp. 802
    • Gannon, J.V.1    Lane, D.P.2
  • 54
    • 0027523461 scopus 로고
    • Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production
    • Baffy G, Miyashita T, Williamson JR, Reed JC: Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J Biol Chem 268:6511, 1993
    • (1993) J Biol Chem , vol.268 , pp. 6511
    • Baffy, G.1    Miyashita, T.2    Williamson, J.R.3    Reed, J.C.4
  • 55
    • 0029022737 scopus 로고
    • Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells
    • Rinaudo MS, Su K, Falk LA, Halder S, Mufson RA: Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells. Blood 86:80, 1995
    • (1995) Blood , vol.86 , pp. 80
    • Rinaudo, M.S.1    Su, K.2    Falk, L.A.3    Halder, S.4    Mufson, R.A.5
  • 56
    • 0025203803 scopus 로고
    • Subcellular distribution of the p53 protein during the cell cycle of balb/c 3T3 cells
    • Shaulsky G, Ben-Ze'ev A, Rotter V: Subcellular distribution of the p53 protein during the cell cycle of balb/c 3T3 cells. Oncogene 5:1710, 1990
    • (1990) Oncogene , vol.5 , pp. 1710
    • Shaulsky, G.1    Ben-Ze'ev, A.2    Rotter, V.3
  • 57
    • 0028841537 scopus 로고
    • An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP-1 cells
    • Zhu H, Fearnhead HO, Cohen GM: An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP-1 cells. FEBS Lett 374:303, 1995
    • (1995) FEBS Lett , vol.374 , pp. 303
    • Zhu, H.1    Fearnhead, H.O.2    Cohen, G.M.3
  • 59
    • 0029670422 scopus 로고    scopus 로고
    • Regulation of p21waf1/cip1 expression by p53-independent pathways
    • Zeng YX, EI-Deiry WS: Regulation of p21waf1/cip1 expression by p53-independent pathways. Oncogene 12:1557, 1996
    • (1996) Oncogene , vol.12 , pp. 1557
    • Zeng, Y.X.1    Ei-Deiry, W.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.