Adenovirus-mediated gene transfer into isolated mouse adult pancreatic islets: Normal β-cell function despite induction of an anti-adenovirus immune response

Human Gene Therapy

Volumn 8, Issue 13, 1997, Pages 1625-1634

  Sigalla, Jeanne ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; INSULIN;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; LEUKOCYTE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; REPORTER GENE; STREPTOZOCIN DIABETES; VIRUS IMMUNITY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA; MURINAE;

EID: 0030714099     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.13-1625     Document Type: Article

References (2)

1. ANEGON, I., DAVID, A., CHARREAU, B., and SOULILLOU, J.P. (1996). Somatic gene transfer in transplantation. In Transplantation Biology: Cellular and Molecular Aspects, N.L. Tilney, T.B. Strom, and L.C. Paul, eds. (Lippincott-Raven Publishers, Philadelphia) p. 689-699.
2. BECKER, T.C., BELTRANDELRIO, H., NOEL, R.J., JOHNSON, J.H., and NEWGARD, G.B. (1994). Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory levels. J. Biol. Chem. 269, 21234-21238.