Electroresponsive pulsatile depot delivery of insulin from poly(dimethylammopropylacrylamide) gel in rats

Journal of Pharmaceutical Sciences

Volumn 86, Issue 11, 1997, Pages 1273-1277

  Kagatani, Seiya ^a   Shinoda, Tatsuki ^a   Konno, Yutaka ^a   Fukui, Muneo ^a   Ohmura, Tadayoshi ^a   Osada, Yoshihito ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE DERIVATIVE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ELECTRIC FIELD; GEL; GLUCOSE BLOOD LEVEL; HORMONE RELEASE; NONHUMAN; PULSATILE FLOW; RAT; RECEPTOR DOWN REGULATION; STIMULUS RESPONSE;

EID: 0030712896     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9700762     Document Type: Article

References (31)

1. Clark, R. G.; Carlsson, L. M.; Robinson, I. C. Growth hormone (GH) secretion in the conscious rat: negative feedback of GH on its own release. J. Endocrinol. 1988, 119, 201-209.
2. Clark, R. G.; Jansson, J. O.; Isaksson, O.; Robinson, I. C. Intravenous growth hormone: growth responses to patterned infusions. J. Endocrinol. 1985, 104, 53-61.
3. Tarquini, B.; Cavallini, V.; Cariddi, A.; Checchi, M.; Sorice, V.; Cecchettin, M. Prominent circadian absorption of intranasal salmon calcitonin (SCT) in healthy subjects. Chronobiol. Int. 1988, 5, 149-152.
4. Avgerinos, P. C.; Schurmeyer, T. H.; Gold, P. W.; Tomail, T. P.; Loriaux, D. L.; Sherins, R. J.; Cutler, G. B., Jr.; Chrousos, G. P. Pulsatile administration of human corticotropin-releasing hormone in patients with secondary adrenal insufficiency: restoration of the normal corticol secretory pattern. J. Clin. Endocrinol. Metab. 1986, 62, 816-821.
5. Chien, Y. W.; Lelawongs, P.; Siddiqui, O.; Sun, Y.; Shi, W. M. Facilitated Transdermal Delivery of Therapeutic Peptides and Proteins by Iontophoretic Delivery Devices. J. Controlled Release, 1990, 73, 263-278.
6. Green, P.; Shroot, B.; Bernerd, F.; Pilgrim, W. R.; Guy, R. H. In vitro and in vivo iontophoresis of a tripeptide across nude rat skin. J. Controlled Release 1992, 20, 209-218.
7. Knoblauch, P.; Moll, F. In vitro pulsatile and continuous transdermal delivery of buserelin by iontophoresis. J. Controlled Release 1993, 26, 203-212.
8. Banga, A. K.; Chien, Y. W. Characterization of in vitro transdermal iontophoretic delivery of insulin. Drug. Dev. Industr. Pharm. 1993, 19, 2069-2087.
9. Heit, M. C.; Monteiro-Riviere, N. A.; Jayes, F. L.; Riviere, J. E. Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): effect of repeated administration. Pharm. Res. 1994, 11, 1000-1003.
10. Riviere, J. E.; Monteiro-Riviere, N. A.; Rogers, R. A.; Bommannan, D.; Tamada, J. A.; Potts, R. O. Pulsatile transdermal delivery using electroporation: drug delivery and skin toxicology. J. Controlled Release 1995, 36, 229-233.
11. Prausnitz, M. R.; Pliquett, U.; Langer, R.; Weaver, J. C. Rapid temporal control of transdermal drug delivery by electroporation. Pharm. Res. 1994, 11, 1834-1837.
12. Mitragotri, S.; Blankschtein, D.; Langer, R. Transdermal drug delivery using low-frequency sonophoresis. Pharm. Res. 1996, 13, 411-420.
13. Shiino, D.; Kataoka, K.; Yokoyama, M.; Okano, T.; Sakurai, Y. Controlled release of insulin from boronic acid gel under physiological conditions. J. Controlled Release 1994, 28, 317-318.
14. Siegel, R. A.; Falamarzian, M.; Firestone, B. A.; Moxley, B. C. pH-controlled release from hydrophobic/polyelectrolyte copolymer gels. J. Controlled Release 1988, 8, 179-182.
15. Gutowska, A.; Bae, Y. H.; Feijen, J.; Kim, S. W. Heparin release from thermosensitive hydrogels. J. Controlled Release 1992, 22, 95-104.
16. Hoffman, A. S. Applications of thermally reversible polymers and gels in therapeutics and diagnostics. J. Controlled Release 1987, 6, 297-305.
17. Supersaxo, A.; Kou, J. H.; Teitelbaum, P.; Maskiewicz, R. Performed porous microspheres for controlled and pulsed release of macromolecules. J. Controlled Release 1993, 23, 157-164.
18. Kost, J.; Wolfrum, J.; Langer, R. Magnetically enhanced insulin release in diabetic rats. J. Biomed. Mater. Res. 1987, 21, 1367-1373.
19. Kwon, I. C.; Bae, Y. H.; Kim, S. W. Heparin release from polymer complex. J. Controlled Release 1994, 30, 155-159.
20. Kwon, I.; Bae, Y. H.; Okano, T.; Kim, S. W. Drug release from electric current sensitive polymers. J. Controlled Release 1991, 17, 149-156.
21. Sawahata, K.; Hara, M.; Yasunaga, H.; Osada, Y. Electrically controlled drug delivery system using polyelectrolyte gels. J. Controlled Release 1990, 14, 253-262.
22. Tomer, R.; Dimitrijevic, D.; Florence, A. T. Electrically controlled release of macromolecules from cross-linked hyaluronic acid gels. J. Controlled Release 1995, 33, 405-413.
23. Hirai, S.; Yashiki, T.; Mima, H. Effect of surfactants on the nasal absorption of insulin in rats. Int. J. Pharm. 1981, 9, 165-172.
24. Kishi, R.; Osada, Y.; Reversible volume change of microparticles in an electric field. J. Chem. Soc., Faraday Trans. 1. 1989, 85, 655-662.
25. Kishi, R.; Hasebe, M.; Kara, M.; Osada, Y. Mechanism and process of chemomechanical contraction of polyelectrolyte gels under electric field. Polym. Adv. Technol. 1990, 1, 19-25.
26. Gong, J. P.; Nitta, T.; Osada, Y. Electrokinetic modeling of the contractile phenomena of polyelectrolyte gels. One-dimensional capillary model. J. Phys. Chem. 1994, 98, 9583-9587.
27. The Merck Index, 7th ed.; Budavari, S., O'Neil, M. J., Smith, A., Heckelman, P. E., Eds.; Merck: Rahway, NJ, 1989; p 790.
28. Jeffrey, P. D.; Coates, J. H. An equilibrium ultracentrifuge study of the effect of ionic strength on the self-association of bovine insulin. Biochemistry 1966, 12, 3820-3824.
29. Pekar, A. H.; Frank, B. H. Conformation of proinsulin. A comparison of insulin and proinsulin self-association at neutral pH. Biochemistry 1972, 11, 4013-4016.
30. Abramson, H. A. Skin reactions. J. Allergy 1941, 12, 169-175.
31. Malanga, I.; Roberto, R. Pharmacologie Choice in Drug Ionophoresis. Boll. Soc. Ital. Farm. Osp. 1985, 31, 263-270.