Non-sedating antihistamines and cardiac arrhythmia

Lancet

Volumn 350, Issue 9085, 1997, Pages 1115-1116

  Rankin, A C ^a  

^a GLASGOW ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; ASTEMIZOLE; FEXOFENADINE; IBUPROFEN; POTASSIUM CHANNEL; TERFENADINE;

ACTION POTENTIAL; ALLERGIC RHINITIS; CARDIOTOXICITY; DRUG FATALITY; HEART ARRHYTHMIA; HUMAN; PRIORITY JOURNAL; QT INTERVAL; RISK ASSESSMENT; SHORT SURVEY; SUDDEN DEATH;

EID: 0030712413     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)63783-X     Document Type: Note

References (11)

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3. RL Woosley Y Chen JP Freiman RA Gillis Mechanisms of the cardiotoxic actions of terfenadine JAMA 269 1993 1532 1536
4. HL Tan CJY Hou MR Lauer RJ Sung Electrophysiologic mechanisms of the long QT interval syndromes and torsades de pointes Ann Intern Med 122 1995 701 714
5. CM Pratt S Ruberg J Morganroth Dose-response relation between terfenadine (Seldane) and the QTc interval in the scalar electrocardiogram: distinguishing a drug effect from spontaneous variability Am Heart J 131 1996 472 480
6. PK Honig DC Wortham K Zamani DP Conner JC Mullin LR Cantilena Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences JAMA 269 1993 1513 1518
7. 1-receptor antagonists astemizole and terfenadine compared with chlopheniramine and pyrilamine Circ Res 76 1995 110 119
8. + channel from human heart Mol Pharmacol 44 1993 1240 1245
9. Lindquist IR Edwards Risks of non-sedating antihistamines Lancet 349 1997 1322
10. CM Pratt RP Hertz BE Ellis SP Crowell W Louv L Moyé Risk of developing life-threatening ventricular arrhythmia associated with terfenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine Am J Cardiol 73 1994 346 352
11. D Thompson G Oster Use of terfenadine and contraindicated drugs JAMA 275 1996 1339 1341