NMDA receptor involvement in neuroplastic changes induced by neonatal capsaicin treatment in trigeminal nociceptive neurons

Journal of Neurophysiology

Volumn 78, Issue 5, 1997, Pages 2799-2803

  Chiang, Chen Yu ^a   Hu, James W ^a   Sessle, Barry J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLOROKYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; STRYCHNINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENERVATION; MALE; NEUROANATOMY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTIVE FIELD; RECEPTOR BINDING; SURVIVAL; TRIGEMINAL NERVE;

EID: 0030712272     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.78.5.2799     Document Type: Article

References (32)

1. BUCK, S. H. AND BURKS, T. F. The neuropharmacology of capsaicin -review of some recent observations. Pharmacol. Rev. 38: 179-226, 1986.
2. 2+ block of NMDA-receptor channels as a mechanism of modulation. Nature 356: 521-523, 1992.
3. CHIANG, C. Y., Hu, J. W., AND SESSLE, B. J. Parabrachial area and nucleus raphe magnus-induced inhibitory effects on the activity of nociceptive and non-nociceptive trigeminal subnucleus caudalis neurones activated by cutaneous or deep inputs. J. Neurophysiol. 71: 2430-2445, 1994.
4. CHIANG, C. Y., SEO, K., Hu, J. W., AND SESSLE, B. J. NMDA receptor involvement in neuroplastic changes induced by neonatal C-fiber depletion in trigeminal brainstem nociceptive neurons of adult rats. Soc. Neurosci. Abstr. 21: 647, 1995.
5. DINGLEDINE, R., KLECKNER, N. W., AND McBAIN, C. J. The glycine coagonist site of the NMDA receptor. In: Excitatory Amino Acids and Neuronal Plasticity, edited by Y. Ben-Ari. New York: Plenum, 1990, p. 17-26.
6. DUBNER, R. AND BASBAUM, A. I. Spinal dorsal horn plasticity following tissue or nerve injury. In: Textbook of Pain (3rd ed.), edited by P.D. Wall and R. Melzack, New York: Churchill Livingstone, 1994, p. 225-241.
7. FITZGERALD, M. Capsaicin and sensory neurones - a review. Pain 15: 109-130, 1983.
8. GAMSE, R., HOLZER, P., AND LEMBECK, F. Decrease of substance P in primary afferent neurones and impairment of neurogenic plasma extravasation by capsaicin. Br. J. Pharmacol. 68: 207-213, 1980.
9. HAMMOND, D. L. AND RUDA, M. A. Developmental alterations in nociceptive threshold, immunoreactive calcitonin gene-related peptide and substance P, and fluoride-resistant acid phosphatase in neonatally capsaicin-treated rats. J. Comp. Neurol. 312: 436-450, 1991.
10. HOLZER, P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev. 43: 143-201, 1991.
11. i elevation in substantia gelatinosa neurons of neonatal rat spinal cord. Brain Res. Dev. Brain Res. 80: 141-148, 1994.
12. Hu, J. W. Response properties of nociceptive and non-nociceptive neurons in the rat's trigeminal subnucleus caudalis (medullary dorsal horn) related to cutaneous and deep craniofacial afferent stimulation and modulation by diffuse noxious inhibitory controls. Pain 41: 331-345, 1990.
13. Hu, J. W., DEMARO, J. A., KWAN, C. L., SESSLE, B. J., AND JACQUIN, M. F. Neonatal capsaicin effects on infraorbital nerve, plasma extravasation and principalis receptive fields. Soc. Neurosci. Abstr. 22: 758, 1996.
14. JOHNSON, J. W. AND ASCHER, P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325: 529-531, 1987.
15. KANGRGA, I. AND RANDIC, M. Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice. J. Neurosci. 10: 2026-2038, 1990.
16. KEMP, J. A., FOSTER, A. C., LEESON, P. D., PRIESTLEY, T., TRIDGETT, R., IVERSEN, L. L., AND WOODRUFF, G. N. 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc. Natl. Acad. Sci. USA 85: 6547-6550, 1988.
17. KWAN, C. L., Hu, J. W., AND SESSLE, B. J. Neuroplastic effects of neonatal capsaicin on neurons in adult rat trigeminal nucleus principalis and subnucleus oralis. J. Neurophysiol 75: 298-310, 1996.
18. MAO, J., PRICE, D. D., AND MAYER, D. J. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain 62: 259-274, 1995.
19. MACDONALD, J. F. AND NOWAK, L. M. Mechanisms of blockade of excitatory amino acid receptor channels. Trends Pharmacol. Sci. 11: 167-172, 1990.
20. NAGY, J. I. AND HUNT, S. P. The termination of primary afferents within the rat dorsal horn: evidence for arrangement following capsaicin treatment. J. Comp. Neurol. 218: 145-158, 1983.
21. REN, K., HYLDEN, J.L.K., WILLIAMS, G. M., RUDA, M. A., AND DUBNER, R. The effects of a non competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain 50: 331-344, 1992.
22. REN, K., WILLIAMS, G. M., RUDA, M. A., AND DUBNER, R. Inflammation and hyperalgesia in rats neonatally treated with capsaicin: effects on two classes of nociceptive neurons in the superficial dorsal horn. Pain 59: 287-300, 1994.
23. SESSLE, B. J., CHIANG, C. Y., AND Hu, J. W. Changes in properties of trigeminal brainstem nociceptive neurons as a result of neonatal C-fiber depletion (Abstract). Can. J. Physiol. Pharmacol. 25: 141, 1995a.
24. SESSLE, B. J., KWAN, C. L., AND Hu, J. W. C-fiber depletion alters properties of low-threshold trigeminal brainstem neurones. J. Dent. Res. 74: 527, 1995b.
25. SHORTLAND, P., MOLANDER, C., WOOLF, C. J., AND FITZGERALD, M. Neonatal capsaicin treatment induces invasion of the substantia gelatinosa by the terminal arborization of hair follicle afferents in the rat dorsal horn. J. Comp. Neurol. 296: 23-31, 1990.
26. SKILLING, S. R. AND LARSON, A. A. Capsaicin inhibits whereas rhizotomy potentiates substance P-induced release of excitatory amino acids in the rat spinal cord in vivo. Neurosci. Lett. 150: 107-110, 1993.
27. URBAN, L. AND DRAY, A. Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro. Neuroscience 47: 693-702, 1992.
28. URBAN, L., THOMPSON, S.W.N., AND DRAY, A. Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci. 17: 432-438, 1994.
29. WALL, P. D., FITZGERALD, M., NUSSBAUMER, J. C., VAN DER Loos, H., AND DEVOR, M. Somatotopic maps are disorganized in adult rodents treated neonatally with capsaicin. Nature 295: 691-693, 1982.
30. WOOLF, C. J. Central mechanisms of acute pain. In: Proceedings of the Vlth World Congress on Pain, edited by M. R. Bond, J. E. Charlton, and C. J. Woolf. Amsterdam: Elsevier, 1991, p. 25-34.
31. Yu, X. M., SESSLE, B. J., AND Hu, J. W. Differential effects of cutaneous and deep application of inflammatory irritant on mechanoreceptive field properties of trigeminal brain stem nociceptive neurons. J. Neurophysiol. 70: 1704-1707, 1993.
32. Yu, X. M., SESSLE, B. J., HAAS, D. A., Izzo, A., VERNON, H., AND Hu, J. W. Involvement of NMDA receptor mechanisms in jaw electromyographic activity and plasma extravasation induced by inflammatory irritant application to temporomandibular joint region of rats. Pain 68: 169-178, 1996.