A single dose of intravenously injected poloxamine-coated long-circulating particles triggers macrophage clearance of subsequent doses in rats

Clinical Science

Volumn 93, Issue 4, 1997, Pages 371-379

  Moghimi, S M ^a   Gray, T ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Long circulating particles; Macrophage clearance; Nanospheres; Poloxamine coated particles

Indexed keywords

COPOLYMER; DRUG CARRIER; NANOPARTICLE; POLOXAMINE 908; POLYSTYRENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL POPULATION; CIRCULATION TIME; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG UPTAKE; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; KUPFFER CELL; MACROPHAGE; MALE; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; RAT; RETICULOENDOTHELIAL SYSTEM; SPLEEN CELL;

EID: 0030712178     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0930371     Document Type: Article

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