Efficacy of taxol in the orpk mouse model of polycystic kidney disease

Pediatric Nephrology

Volumn 11, Issue 6, 1997, Pages 728-733

  Sommardahl, Carla S ^a   Woychik, Richard P ^b   Sweeney, William E ^c   Avner, Ellis D ^c   Wilkinson, J Erby ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Biliary hyperplasia; Epidermal growth factor receptor; Polycystic kidney disease; Renal cysts; Taxol

Indexed keywords

LIVER ENZYME; PACLITAXEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME BLOOD LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY POLYCYSTIC DISEASE; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; SERUM OSMOLALITY; SURVIVAL RATE; URINE OSMOLALITY; WEIGHT GAIN;

AGING; ALKALINE PHOSPHATASE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; GENES; IMMUNOHISTOCHEMISTRY; KIDNEY; LIVER; MICE; MUTATION; OSMOLAR CONCENTRATION; PACLITAXEL; POLYCYSTIC KIDNEY DISEASES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 0030710548     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004670050376     Document Type: Article

References (42)

1. Blyth H, Ockenden BG (1971) Polycystic diseases of kidneys and liver presenting in childhood. J Med Genet 8: 257-284
2. Fick GM, Gabow PA (1994) Heredity and acquired cystic disease of the kidney. Kidney Int 46: 951-964
3. Bernstein J, Gardner KD (1986) Renal cystic disease and renal dysplasia. In: Walsh PC, et al (eds) Campbell's urology. Saunders, Philadelphia, pp 1760-1818
4. Lippert MC (1991) Renal cystic disease In: Gillenwater JY, et al (eds) Adult and pediatric urology. Mosby, Chicago, pp 711-743
5. Fick GM, Gabow PA (1994) Natural history of autosomal dominant polycystic kidney disease. Annu Rev Med 45: 23-29
6. Fick GM, Duley IT, Johnson AM, et al (1994) The spectrum of autosomal dominant polycystic kidney disease in children. J Am Soc Nephrol 4: 1654-1660
7. Grantham JJ (1993) Polycystic kidney disease: heredity and acquired. Adv Intern Med 38: 409-420
8. Gabow PA (1993) Autosomal dominant polycystic kidney disease. N Engl J Med 329: 332-342
9. Zerres K, Mucher G, Bachner L, et al (1994) Mapping of the gene for autosomal recessive polycystic kidney disease (ARPKD) to chromosome 6p21-cen. Nature Genet 7: 429-432
10. Dalgaard OZ (1957) Bilateral polycystic disease of the kidneys: a follow-up of two-hundred and eighty-four patients and their families. Acta Med Scand [Suppl] 328: 1-255
11. Gabow PA, Schrier RW (1989) Pathophysiology of adult polycystic kidney disease. Adv Nephrol 18: 19-32
12. Schafer K, Gretz N, Bader M (1994) Characterization of the Han: SPRD rat model for hereditary polycystic kidney disease. Kidney Int 46: 134-152
13. Gattone VH, Grantham JJ (1991) Understanding human cystic disease through experimental models. Semin Nephrol 11: 617-631
14. Gattone VH, Calvet JP (1991) Murine infantile polycystic kidney disease: a role for reduced renal epidermal growth factor. Am J Kidney Dis 17: 606-607
15. Gattone VH, Kraybill AL, Gudapaty S, et al (1990) Autosomal dominant polycystic kidney disease (ADPKD) in the rat. J Am Soc Nephrol 1: 629
16. Avner ED, Studnicki FE, Young MC, et al (1987) Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation. Pediatr Nephrol 1: 587-596
17. Avner ED, Sweeney WE, Young MC, et al (1988) Congenital murine polycystic kidney disease. II. Pediatr Nephrol 2: 210-218
18. Takahaski H, Calvet JP, Dittemore-Hoover D, et al (1991) A hereditary model of slowly progressive polycystic kidney disease in the mouse. J Am Soc Nephrol 1: 980-989
19. Flaherty L, Bryda EC, Collins D, et al (1995) New mouse model for polycystic kidney disease with both recessive and dominant gene effects. Kidney Int 47: 552-558
20. Atala A, Freeman MR, Mandell J, Beier DR (1993) Juvenile cystic kidneys(jck): a new mouse mutation which causes polycystic kidneys. Kidney Int 43: 1081-1085
21. Ozawa Y, Nauta J, Sweeney WE, Avner ED (1993) A new murine model of autosomal recessive polycystic kidney disease. Nippon Jinzo Gakkai Shi 35: 349-354
22. Nauta J, Ozawa Y, Sweeney WE, et al (1993) Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney diseases. Pediatr Nephrol 7: 163-172
23. Moyer JH, Lee-Tischler MJ, Kwon HY, et al (1994) Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 264: 1329-1333
24. Avner ED (1993) Epithelial polanty and differentiation in polycystic kidney disease. J Cell Sci [Suppl] 17: 217-222
25. Grantham JJ (1990) Polycystic kidney disease: neoplasia in disguise. Am J Kidney Dis 15: 110-116
26. Grantham JJ (1994) Pathogenesis of renal cyst expansion: opportunities for therapy. Am J Kidney Dis 23: 210-218
27. Nauta J, Sweeney WE, Avner ED (1991) Epithelial hyperplasia and cell polarity abnormalities in murine autosomal recessive polycystic kidney disease. J Am Soc Nephrol 1: 257
28. Wilson PD (1991) Aberrant epithelial cell growth in autosomal dominant polycystic kidney disease. Am J Kidney Dis 17: 634-637
29. Shriek JJ, Onuchic LF, Reeders ST, et al (1995) Characterization of the human homologue of the mouse Tg737 candidate polycystic kidney disease gene. Hum Mol Genet 4: 559-567
30. Rowinsky EK, Donehower RC (1995) Paclitaxel (taxol). N Engl J Med 332: 1004-1014
31. Woo DDL, Miao SYP, Pelayo JC, Woolf AS (1994) Taxol inhibits progression of congenital polycystic disease. Nature 368: 750-753
32. Sweeney WE Jr, Avner ED (1991) Intact organ culture of murine metanephrons. J Tissue Cult Methods 13: 163-168
33. Orellana SA, Sweeney WE, Neff CD, Avner ED (1995) Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int 47: 490-499
34. Kris RM, Lax I, Gullic W, Waterfield MD, Ullrich A, Fridkin M, Schlessinger J (1985) Antibodies against a synthetic peptide as a probe for the kinase activity of avian EGF receptor and v-erbGB protein. Cell 40: 619-625
35. Yoder BK, Richards WG, Sommardahl CS, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP (1996) Functional correction of renal defects in a mouse model for ARPKD through the expression of the cloned wild-type TG737 gene Kidney Int 50: 1158-1165
36. Avner ED (1993) Renal developmental diseases. Semin Nephrol 13: 427-435
37. Avner ED, Sweeney WE Jr (1992) Altered membrane localization of NaKATPase and epidermal growth factor receptor during in vitro modulation of collecting tubule cystogenesis (abstract). J Am Soc Nephrol 2 673
38. Harris RC (1991) Potential physiologic roles for epidermal growth factor in the kidney. Am J Kidney Dis 17: 627-630
39. Iakoubova OA, Dushkin H, Beier DR (1995) Localization of a murine recessive polycystic kidney disease mutation and modifying loci that affect disease severity. Genomics 26: 107-114
40. D'Agata BD, Jonas MM, Perez-Atayde AR, Guay-Woodford LM (1994) Combined cystic disease of the liver and kidney. Semin Liver Dis 14: 215-228
41. McDonald RA, Avner ED (1991) Inherited polycystic kidney disease in children. Semin Nephrol 11: 632-642
42. Richards WG, Yoder BK, Sweeney WE, Wilkinson JE, Avner ED, Woychik RP (1996) A hypomorphic allele of the EGF-R (waved-2) abrogates collecting duct cyst formation in a mouse polycystic kidney disease model (abstract). J Am Soc Nephrol 7: 1604