Synthesis of (+)-(1'R,2'S) and (1'S,2'R)-6,11-Dimethyl-1,2,3,4,5,6- hexahydro-3-[[2'-(alkoxycarbonyl)-2'-phenylcyclopropyl]methyl]-2,6-methano- 3-benzazocin-8-ol. Comparison of the affinities for σ1 and opioid receptors with in the diastereoisomeric MPCB and CCB

Farmaco

Volumn 52, Issue 6-7, 1997, Pages 471-476

  Ronsisvalle, G ^a   Prezzavento, O ^a   Pasquinucci, L ^a   Pappalardo, M S ^a   Marrazzo, A ^a   Vittorio, F ^a   Carboni, L ^a   Spampinato, S ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

6,11 DIMETHYL 1,2,3,4,5,6 HEXAHYDRO 3 [[2' (METHOXYCARBONYL) 2' PHENYLCYCLOPROPYL]METHYL] 2,6 METHANO 3 BENZAZOCIN 8 OL; BENZAZOCINE DERIVATIVE; OPIATE RECEPTOR; PENTAZOCINE; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; DIASTEREOISOMER; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; MALE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RECEPTOR AFFINITY;

ANIMALS; BRAIN; CYCLAZOCINE; GUINEA PIGS; ISOMERISM; MALE; MOLECULAR STRUCTURE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; RECEPTORS, SIGMA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030710085     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)