Synthetic studies of vitamin D analogs. XXIV. Synthesis of active vitamin D3 analogs substituted at the 2β-position and their preventive effects on bone mineral loss in ovariectomized rats

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 10, 1997, Pages 1626-1630

  Ono, Yoshiyuki ^a   Watanabe, Hiroyoshi ^a   Shiraishi, Ayako ^a   Takeda, Satoshi ^a   Higuchi, Yoshinobu ^a   Sato, Katsuhiko ^a   Tsugawa, Naoko ^b   Okano, Toshio ^b   Kobayashi, Tadashi ^b   Kubodera, Noboru ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

1 ,25 dihydroxy 2 (3 hydroxypropoxy)vitamin D3; 1 ,25 dihydroxyvitamin D3; 1 hydroxyvitamin D3; ED 71; Ovariectomized rat; Vitamin D3 analog

Indexed keywords

COLECALCIFEROL DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; BONE ATROPHY; BONE DENSITY; BONE MINERALIZATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; NONHUMAN; ORAL DRUG ADMINISTRATION; OSTEOPOROSIS; OVARIECTOMY; PHASE 1 CLINICAL TRIAL; RAT; REVIEW; STRUCTURE ACTIVITY RELATION; VITAMIN METABOLISM;

EID: 0030709350     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.1626     Document Type: Review

References (12)

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