Pathways for oxidation of low density lipoprotein by myeloperoxidase: Tyrosyl radical, reactive aldehydes, hypochlorous acid and molecular chlorine

BioFactors

Volumn 6, Issue 2, 1997, Pages 145-155

  Heinecke, Jay W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3 Chlorotyrosine; Atherosclerosis; Chlorine gas; Dityrosine; Phagocyte

Indexed keywords

ALDEHYDE; CHLORINE; CHOLESTEROL; HYPOCHLOROUS ACID; LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE;

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; ENZYME ACTIVITY; HUMAN; LIPID OXIDATION; LIPID PEROXIDATION; PATHOGENESIS; PHAGOCYTE; PRIORITY JOURNAL; REVIEW;

EID: 0030708895     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520060208     Document Type: Review

References (3)

1. J.L. Witztum and D. Steinberg, Role of oxidized low density lipoprotein in atherogenesis, J. Clin. Invest. 88 (1991), 1785-1792.
2. E.R. Stadtman, Protein oxidation and aging, Science 257 (1992), 1220-1224.
3. B.N. Ames, M.K. Shigenaga and T.M. Hagen, Oxidants, antioxidants, and the degenerative diseases of aging, Proc. Natl. Acad. Sci. 90 (1993), 7915-7922.