Interleukin-4 ameliorates experimental glomerulonephritis and up- regulates glomerular gene expression of IL-1 decoy receptor

Kidney International

Volumn 52, Issue 5, 1997, Pages 1224-1231

  Tam, Frederick W K ^a   Smith, Jennifer ^b   Karkar, Ayman M ^b   Pusey, Charles D ^b   Rees, Andrew J ^b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b NONE

Author keywords

Decoy receptor; Gene expression; Glomerulonephritis; Interleukin

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 4; RECOMBINANT INTERLEUKIN 4;

ACUTE GLOMERULONEPHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; GENE EXPRESSION; GLOMERULUS BASEMENT MEMBRANE; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY INJURY; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; RECEPTOR UPREGULATION; TISSUE INJURY;

EID: 0030707670     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1997.447     Document Type: Article

References (57)

1. UNANUE ER, DIXON FJ: Experimental glomerulonephritis: Immunological events and pathogenetic mechanisms. Adv Immunol 6:1-90, 1967
2. SCHREINER GF, CONTRAN RS, PARDO V, UNANUE ER: A mononuclear cell component in experimental immunological glomerulonephritis. J Exp Med 147:369-383, 1978
3. CATTELL V, SMITH J, COOK HT: Prostaglandin E1 suppresses macrophage infiltration and ameliorates injury in an experimental model of macrophage-dependent glomerulonephritis. Clin Exp Immunol 79: 260-265, 1990
4. UNANUE ER, DIXON FJ: Experimental glomerulonephritis VI: The autologous phase of nephrotoxic serum nephritis. J Exp Med 121:715-725, 1965
5. LAN HY, NIKOLIC-PATERSON DJ, ZARAMA M, VANNICE JL, ATKINS RC: Suppression of experimental crescentic glomerulonephritis by interleukin-1 receptor antagonist. Kidney Int 43:479-485, 1993
6. DINARELLO CA: Interleukin-1, in The Cytokine Handbook, edited by THOMSON AW, San Diego, Academic Press. 1994, p 186
7. BEVILACQUA MP, STENGELIN S, GIMBRONE MA, SEED B: Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 243: 1160-1165, 1989
8. POBER JS, GIMBRONE MA JR, LAPIERRE LA, MENDRICK DL, FIERS W, ROTHLEIN R, SPRINGER TA: Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J Immunol 137:1893-1896, 1986
9. STRIETER RM, KUNKEL SL, SHOWELL HJ, REMICK DG, PHAN SH, WARD PA, MARKS RM: Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1beta. Science 243:1467-1469, 1989
10. TOMOSUGI NI, CASHMAN SJ, HAY H, PUSEY CD, EVANS DJ, SHAW A, REES AJ: Modulation of antibody-mediated glomerular injury in vivo by bacterial lipopolysaccharide, tumor necrosis factor, and IL-1. J Immunol 142:3083-3090, 1989
11. PRIESTLE JP, SCHAR HP, GRUTTER MG: Crystallographic refinement of interleukin 1 beta at 2.0 A resolution. Proc Natl Acad Sci USA 86:9667-9671, 1989
12. SIMS JE, MARCH CJ, COSMAN D, WIDMER MB, MACDONALD HR, MCMAHAN CJ, GRUBIN CE, WIGNALL JM, JACKSON JL, CALL SM, FRIEND D, ALPERT AR, GILLIS S, URDAL DL, DOWER SK: cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241:585-589, 1988
13. COLOTTA F, RE F, MUZIO M, BERTINI R, POLENTARUTTI N, SIRONI M, GIRI JG, DOWER SK, SIMS JE, MANTOVANI A: Interleukin-1 type II receptor: A decoy target for IL-I that is regulated by IL-4. Science 261:472-475, 1993
14. COLOTTA F, SACCANI S, GIRI JG, DOWER SK, SIMS JE, INTRONA M, MANTOVANI A: Regulated expression and release of the IL-1 decoy receptor in human mononuclear phagocytes. J Immunol 156:2534-2541, 1996
15. RE F, SIRONI M, MUZIO M, MATTEUCCI C, INTRONA M, ORLANDO S, PENTON-ROL G, DOWER SK, SIMS JE, COLOTTA F, MANTOVANI A: Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: A surface "receptor" with anti-interleukin-1 function. J Exp Med 183:1841-1850, 1996
16. EISENBERG SP, EVANS RJ, AREND WP, VERDERBER E, BREWER MT, HANNUM CH, THOMPSON RC: Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 343:341-346, 1990
17. GRANOWITZ EV, CLARK BD, VANNIER E, CALLAHAN MV, DINARELLO CA: Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes. Blood 79:2356-2363, 1992
18. TAM FWK, SMITH J, CASHMAN SJ, WANG Y, THOMPSON EM, REES AJ: Glomerular expression of interleukin-1 receptor antagonist and interleukin-1β genes in antibody-mediated glomerulonephritis. Am J Pathol 145:126-136, 1994
19. COLOTTA F, RE F, MUZIO M, POLENTARUTTI N, MINTY A, CAPUT D, FERRARA P, MANTOVANI A: Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells. J Biol Chem 269:12403-12406, 1994
20. VANNIER E, MILLER LC, DINARELLO CA: Coordinated antiinflammatory effects of interleukin 4: Interleukin 4 suppresses interleukin 1 production hut up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proc Natl Acad Sci USA 89:4076-4080, 1992
21. MENDEZ-SAMPERIO P, HERNANDEZ-GARAY M, BADILLO-FLORES A, NUNEZ-VAZQUEZ A: Down-modulation of mycobacterial-induced IL-1 beta production in human mononuclear cells by IL-4. Clin Exp Immunol 104:374-379, 1996
22. JORDAN M, OTTERNESS IG, NG R, GESSNER A, ROLLINGHOFF M, BEUSCHER HU: Neutralization of endogenous IL-6 suppresses induction of IL-1 receptor antagonist. J Immunol 154:4081-4090, 1995
23. CASSATELLA MA, MEDA L, GASPERINI S, CALZETTI F, BONORA S: Interleukin 10 (1L-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNA degradation. J Exp Med 179:1695-1699, 1994
24. MUZIO M, RE F, SIRONI M, POLENTARUTTI N, MINTY A, CAPUT D, FERRARA P, MANTOVANI A, COLOTTA F: Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells. Blood 83:1738-1743, 1994
25. TURNER M, CHANTRY D, KATSIKIS P, BERGER A, BRENNAN FM, FELDMANN M: Induction of the interleukin 1 receptor antagonist protein by transforming growth factor-β. Eur J Immunol 21:1635-1639, 1991
26. ABRAMSON SL, GALLIN JI: IL-4 inhibits superoxide production by human mononuclear phagocytes. J Immunol 144:625-630, 1990
27. LACRAZ S, NICOD L, GALVE-DE ROCHEMONTEIX B, BAUMBERGER C: Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4. J Clin Invest 90:382-388, 1992
28. DE VELDE AA, HUIJBENS RJF, DE VRIES JE, FIGDOR CG: IL-4 decreases FcγR membrane expression and FcγR-mediated cytotoxic activity of human monocytes. J Immunol 144:3046-3051, 1990
29. BOGDAN C, VODOVOTZ Y, NATHAN C: Macrophage deactivation by interleukin 10. J Exp Med 174:1549-1555, 1991
30. COFFMAN RL, VARKILA K, SCOTT P, CHATELAIN R: Role of cytokines in the differentiation of CD4+ T cell-subsets in vivo. Immunol Rev 12:189-207, 1992
31. CHATELAIN R, VARKILA K, COFFMAN RL: IL-4 induces a Th2 response in Leishmania major-infected mice. J Immunol 148:1182-1187, 1992
32. REYNOLDS J, PUSEY CD: In vivo treatment with a monoclonal antibody to T helper cells in experimental autoimmune glomerulonephritis. Clin Exp Immunol 95:122-127, 1994
33. BHAN AK, SCHNEEBERGER EE, COLLINS AB, MCCLUSKEY RT: Evidence for a pathogenic role of a cell-mediated immune mechanism in experimental glomerulonephritis. J Exp Med 148:246-260, 1978
34. MCMAHAN CJ, SLACK JL, MOSLEY B, COSMAN D, LUPTON SD, BRUNTON LL, GRUBIN CE, WIGNALL JM, JENKINS NA, BRANNAN CI, COPELAND NG, HUEBNER K, CROCE CM, CANNIZZARRO LA, BENJAMIN D, DOWER SK, SPRIGGS MK, SIMS JE: A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J 10:2821-2832, 1991
35. COWAN NJ, DOBNER PR, FUCHS EV, CLEVELAND DW: Expression of human alpha tubulin genes: Interspecies conservation of 3′ untranslated regions. Mol Cel Biol 3:1738-1745, 1983
36. MCKNIGHT AJ, CLASSON BJ: Biochemical and immunological properties of rat recombinant interleukin-2 and interleukin-4. Immunology 75:286-292, 1992
37. RAMIREZ F, FOWELL DJ, PUKLAVEC M, SIMMONDS S, MASON D: Glucocorticoids promote a Th2 cytokine response by CD4+ T cells in vitro. J Immunol 156:2406-2412, 1996
38. COOK HT, CATTELL V, SMITH J, SALMON JA, MONCADA S: Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat. Clin Nephrol 26:195-199, 1986
39. DAMOISEAUX JGMC, HUITINGA I, DOPP EA, DIJKSTRA CD: Expression of the ED3 antigen on rat macrophages in relation to experimental autoimmune diseases. Immunobiol 184:311-320, 1992
40. SAMBROOK J, FRITSCH EF, MANIATIS T: Preparation of radiolabeled DNA and RNA probes, in Molecular Cloning: A Laboratory Manual, edited by FORD N, NOLAN C, FERGUSON M, New York. Cold Spring Harbor Laboratory Press, 1989, p 10.1
41. COOK HT, SMITH J, CATTELL V: Isolation and characterization of inflammatory leukocytes from glomeruli in an in situ model of glomerulonephritis in the rat. Am J Pathol 126:126-136, 1987
42. ABBOTT F, TAM FWK, RYAN JJ, REES AJ: Human mesangial cells synthesize interleukin-1α but not interleukin-1β, interleukin-1 receptor antagonist or tumour necrosis factor. Nephrol Dial Transplant 7:997-1001, 1992
43. ALLEN JB, WONG HL, COSTA GL, BIENKOWSKI MJ, WAHL SM: Suppression of monocye function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis. J Immunol 151:4344-4351, 1993
44. MULLIGAN MS, JONES ML, VAPORCIYAN AA, HOWARD MC, WARD PA: Protective effects of IL-4 and IL-10 against immune complex-induced lung injury. J Immunol 151:5666-5674, 1993
45. WEST GA, MATSUURA T, LEVINE AD, KLEIN JS, FIOCCHI C: Interleukin-4 in inflammatory bowel disease and mucosal immune reactivity. Gastroenterology 110:1683-1695, 1996
46. BERMAN MA, SANDBORG CI, WANG Z, IMFELD KL, ZALDIVAR FJR, DADUFAIZA V, BUCKINGHAM BA: Decreased IL-4 production in new onset type I insulin-dependent diabetes mellitus. J Immunol 157: 4690-4696, 1996
47. OKADA H, KONISHI K, NAKAZATO Y, KANNO Y, SUZUKI H, SAKAGUCHI H, SARUTA T: Interleukin-4 expression in mesangial proliferative glomerulonephritis. Am J Kidney Dis 23:242-246, 1994
48. BALLARDIE FW, GORDON MT, SHARPE PT, DARVILL AM, CHENG H: Intrarenal cytokine mRNA expression and location in normal and IgA nephropathy tissue: TGF alpha, TGF beta, IGF 1, IL-4 and IL-6. Nephrol Dial Transplant 9:1545-1552, 1994
49. 4 (IL-4) and interleukin-4 receptor (IL-4R) in human kidney. (abstract) J Am Soc Nephrol 6:865, 1995
50. TIPPING PG, KITCHING AR, HUANG XR, MUTCH DA, HOLDSWORTH SR: Immune modulation with interleukin-4 and interleukin-10 prevents crescent formation and glomerular injury in experimental glomerulonephritis. Eur J Immunol 27:530-537, 1997
51. VAN DEN BERG TK, BREVE JJP, DAMOISEAUX JGMC, DOPP EA, KELM S, CROCKER PR, DIJKSTRA CD, KRAAL G: Sialoadhesin on macrophages: Its identification as lymphocyte adhesion molecule. J Exp Med 176:647-655, 1992
52. DIJKSTRA CD, DOPP EA, JOLING P, KRAAL G: The heterogeneity of mononuclear phagocytes in lymphoid organs. Distinct macrophage subpopulation in the rat recognised by mononuclear antibody ED1, ED2, ED3. Immunology 54:589-599, 1985
53. MCWILLIAM AS, TREE P, GORDON S: Interleukin-4 regulates induction of sialoadhesin, the macrophage sialic acid-specific receptor. Proc Natl Acad Sci USA 89:10522-10526, 1992
54. VAN DEN BERG TK, VAN DIE I, DE LAVALETTE CR, DOPP EA, SMIT LD, VAN DEN MEIDE PH, TILDERS FJH, CROCKER PR, DIJKSTRA CD: Regulation of sialoadhesin expression on rat macrophages: Induction by glucocorticoids and enhancement by IFN-β, IFN-γ, IL-4 and lipopolysaccharide. J Immunol 157:3130-3138, 1996
55. MOUTABARRIK A, ISHIBASHI M, NAMIKI M, KAMEOKA H, KOKADO Y, YOSHIZAKI K, TAKANO Y, YOKOKAWA K, TAKAHARA S, SEGUCHI T, SONODA T, ZAID D, OKUYAMA A: Disparate regulation of interleukin-6 secretion from blood monocytes and vascular endothelial cells by interleukin-4. Transplant Proc 24:2898-2899, 1992
56. LIEW FY, LI Y, SEVERN A, MILLOTT S, SCHMIDT J, SALTER M, MONCADA S: A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages. Eur J Immunol 21:2489-2494, 1991
57. KATOH T, LAKKIS FG, MAKITA N, BADR KF: Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis. Kidney Int 46:341-349, 1994