The γ-carboxylation recognition site is sufficient to direct vitamin K- dependent carboxylation on an adjacent glutamate-rich region of thrombin in a propeptide-thrombin chimera

Journal of Biological Chemistry

Volumn 272, Issue 45, 1997, Pages 28258-28262

  Furie, Barbara C ^a   Ratcliffe, Jennifer V ^a,b   Tward, Jonathan ^a   Jorgensen, Maria J ^a,c   Blaszkowsky, Lawrence S ^a   DiMichele, Donna ^a,d   Furie, Bruce ^a,e  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; GLUTAMIC ACID; MUTANT PROTEIN; PEPTIDE; PROTHROMBIN; THROMBIN; VITAMIN K GROUP;

ANIMAL CELL; ARTICLE; CARBOXYLATION; CHO CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION;

AMINO ACID SEQUENCE; ANIMALS; CARBON-CARBON LIGASES; CHO CELLS; CRICETINAE; DISULFIDES; GLUTAMIC ACID; KRINGLES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; PROTHROMBIN; RECOMBINANT FUSION PROTEINS; THROMBIN; VITAMIN K;

EID: 0030707636     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.45.28258     Document Type: Article

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