A pharmacogenetic study of trimethylaminuria in orientals

Pharmacogenetics

Volumn 7, Issue 6, 1997, Pages 497-501

  Thithapandha, Amnuay ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

FMO3; Genetics of disease; Oriental subjects; Trimethylaminuria

Indexed keywords

TRIMETHYLAMINE;

ADULT; ARTICLE; ASIAN; AUTOSOMAL RECESSIVE DISORDER; CASE REPORT; FEMALE; HUMAN; HUMAN EXPERIMENT; INBORN ERROR OF METABOLISM; MALE; NORMAL HUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; THAILAND; URINARY EXCRETION;

EID: 0030707609     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199712000-00008     Document Type: Article

References (16)

1. Al-Waiz M, Ayesh R, Mitchell SC, Idle JR, Smith RL. Trimethylaminuria (fish -odour syndrome) - an inborn error of oxidative metabolism. Lancet 1987a: 1, 634-635.
2. Al-Waiz M, Ayesh R, Mitchell SC, Idle JR, Smith RL. A genetic polymorphism of the N-oxidation of trimethylamine in humans. Clin Pharmacol Ther 1987b: 42, 588-594.
3. Al-Waiz M, Ayesh R, Mitchell SC, Idle JR, Smith RL. Disclosure of the metabolic retroversion of trimethylamine N-oxide in humans - a pharmacogenetic approach. Clin Pharmacol Ther 1987c: 42, 608-612.
4. Al-Waiz M, Ayesh R, Mitchell SC, Idle JR, Smith RL. Trimethylaminuria (fish-odour syndrome): a study of an affected family. Clin Sci 1988: 74, 231-236.
5. Arbuthnot J. An essay concerning the nature of ailments. London: J. Tonson. 1735: 82-83.
6. Ayesh R, Smith RL. Genetic polymorphism in human toxicology. In: Turner P, Volans GN, eds. Recent advances in clinical pharmacology and toxicology. Edinburgh: Churchill-Livingstone, 1989: 137-157.
7. Ayesh R, Mitchell SC, Zhang A, Smith RL. The fish-odour syndrome: Biochemical, familial and clinical aspect. Br Med J 1993: 307, 655-657.
8. Brand JM, Galask RP. Trimethylamine - the substance mainly responsible for the fish odour often associated with bacterial vaginosis. Obstet Gynecol 1986: 68, 682-685.
9. Cholerton S, Smith RL. Human pharmacogenetics of nitrogen oxidations. In: Hlavica P, Damani LA, eds. N-oxidation of drug - biochemistry, pharmacology, toxicology. London: Chapman & Hall, 1991: 107-131.
10. Dolphin CT, Cullingford TE, Shephard EA, Smith RL, Philips IR. Differential development and tissue-specific regulation of expression of the gene encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FMO4. Eur J Biochem 1996: 235, 683-689.
11. Dolphin CT, Riley JH, Shephard EA, Smith RL, Philips IR. The gene encoding flavin-containing monooxygenase 3 of man: structural organization and identification of a mutation associated with the inherited disorder, fish-odour syndrome. Pharmacogenetics 1947: in press.
12. Humbert JR, Hammond KB, Hathaway WE, Marcoux JG, O'Brien D. Trimethylaminuria: the fish-odour syndrome. Lancet 1970: 1, 770-771.
13. McCombie RR, Dolphin CT, Povey S, Philips IR, Shephard EA. Localization of human flavin-containing monooxygenase genes FMO2 and FMO5 to chromosome 1q. Genomics 1996: in press.
14. Mitchell SC, Zhang AQ, Barrett T, Ayesh R, Smith RL. Studies on the discontinuous N-oxidation of trimethylamine among Jordanian. Ecuadorian and New Guineun populations. Pharmacogenetics 1997: 7, 45-50.
15. Shelley ED, Shelley WD. The fish-odour syndrome - trimethylaminuria. JAMA 1984: 251, 253-255.
16. Zhang AQ, Mitchell SC, Ayesh R, Smith RL. Determination of trimethylamine and related aliphatic amines in human urine by head-space gas chromatography. J Chromatography 1942: 584, 141-145.