SJA6017, a newly synthesized peptide aldehyde inhibitor of calpain: Amelioration of cataract in cultured rat lenses

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1361, Issue 3, 1997, Pages 304-312

  Fukiage, Chiho ^a,b   Azuma, Mitsuyoshi ^a,b   Nakamura, Yoshikuni ^b   Tamada, Yoshiyuki ^b   Nakamura, Masayuki ^b   Shearer, Thomas R ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b SENJU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Calcium ionophore A23187; Calpain; Cataract; Proteolysis; SJA6017

Indexed keywords

CALCIMYCIN; CALPASTATIN; SJA 6017; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATARACT; CONTROLLED STUDY; ENZYME INHIBITION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; CALPAIN; CATARACT; CULTURE TECHNIQUES; DIPEPTIDES; ENZYME INHIBITORS; HYDROLYSIS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; SUIDAE;

EID: 0030707575     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(97)00043-4     Document Type: Article

References (24)

1. Croall D.E., DeMartino G.N. Physiol. Rev. 71:1991;813-847.
2. Hightower K.R., Riley M.V., McCready J. Curr. Eye Res. 8:1989;517-521.
3. Truscott R.J., Marcantonio J.M., Tomlinson J., Duncan G. Invest. Ophthalmol. Vis. Sci. 31:1990;2405-2411.
4. Chandrasekher G., Cenedella R.J. Exp. Eye Res. 57:1993;737-745.
5. David L.L., Shearer T.R., Shih M. J. Biol. Chem. 268:1993;1937-1940.
6. David L.L., Calvin H.I., Fu S.-C.J. Invest. Ophthalmol. Vis. Sci. 59:1994;501-504.
7. Azuma M., David L.L., Shearer T.R. Curr. Eye Res. 10:1991;657-666.
8. Azuma M., David L.L., Shearer T.R. Biochim. Biophys. Acta. 1180:1992;215-220.
9. Sanderson J., Marcantonio J.M., Duncan G. Biochem. Biophys. Res. Commun. 218:1996;893-901.
10. Wang K.K.W. Trends Pharmacol. Sci. 11:1990;139-142.
11. Azuma M., Fukiage C., David L.L., Shearer T.R. Exp. Eye Res. 64:1997;529-538.
12. Laemmli U.K. Nature. 227:1970;680-685.
13. Racer K.J., Posner A., Wang K.K.W. Arch. Biochem. Biophys. 319:1995;211-216.
14. Wang K.K.W., Nath R., Posner A., Raser K.J., Buroker-Kilgore M., Hajimohammadreza I., Probert A.W. Jr., Marcoux F.W., Ye Q., Takano E., Hatanaka M., Maki M., Caner H., Collins J.L., Fergus A., Lee K.S., Lunney E.A., Hays S.J., Yuen P.-w. Proc. Natl. Acad. Sci. USA. 93:1996;6687-6692.
15. Wang K.K.W., Posner A., Hajimohammadreza I. BioTechniques. 20:1996;662-668.
16. Schagger H., Jagow G.V. Anal. Biochem. 166:1987;368-379.
17. Towbin H., Steahelin T., Gordon J. Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
18. Azuma M., David L.L., Shearer T.R. Ophthalmic Res. 24:1992;8-14.
19. J. Horwitz, N.S. Jaffe, in: Lens and Cataract, ch. 1, Gower Medical Publishing, New York, 1992.
20. David L.L., Azuma M., Shearer T.R. Invest. Ophthalmol. Vis. Sci. 35:1994;785-793.
21. C. Crawford, Intracellular calcium-dependent proteolysis, in: R.L. Mellgren, T. Murachi (Eds.), CRC Press, Boca Raton, 1990, pp. 75-89.
22. Wang K.K.W., Yuen P.-w. Adv. Pharmacol. 37:1997;117-152.
23. Harris A.S., Croall D.E., Morrow J.S. J. Biol. Chem. 263:1988;15754-15761.
24. Nath R., Raser K.J., Stafford D., Hajimohammadreza I., Posner A., Allen H., Talanian R.V., Yuen P.-w., Gilbertsen R.B., Wang K.K.W. Biochem. J. 319:1996;683-690.