Is halofantrine still advisable in malaria attacks?

Annals of Tropical Medicine and Parasitology

Volumn 91, Issue 7, 1997, Pages 867-873

  Touze, J E ^a   Fourcade, L ^a   Peyron, F ^b   Heno, P ^a   Deharo, J C ^c  

^a SERVICE DE SANTÉ DES ARMÉES   (France)

^b CROIX ROUSSE HOSPITAL   (France)

^c HÔPITAL SAINTE MARGUERITE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; AMPICILLIN; ANTIARRHYTHMIC AGENT; ANTIMALARIAL AGENT; BEPRIDIL; CHLOROQUINE; CICLETANINE; COTRIMOXAZOLE; DEBUTYLHALOFANTRINE; DISOPYRAMIDE; ERYTHROMYCIN; FUROSEMIDE; HALOFANTRINE; INDAPAMIDE; LAXATIVE; MEFLOQUINE; PROBUCOL; QUINIDINE; SOTALOL; TERFENADINE; THIAZIDE DIURETIC AGENT; THIORIDAZINE;

ANAPHYLACTIC SHOCK; ARTICLE; BRAIN DISEASE; CARDIOTOXICITY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CHOICE; DRUG EFFICACY; DRUG FORMULATION; DRUG HALF LIFE; DRUG HYPERSENSITIVITY; DRUG METABOLISM; DRUG SOLUBILITY; DRUG TOLERANCE; HEART ARRHYTHMIA; HEMOLYSIS; HUMAN; MALARIA; MALARIA FALCIPARUM; ORAL DRUG ADMINISTRATION; PILL; PLASMODIUM FALCIPARUM; PRACTICE GUIDELINE; PRESCRIPTION; PRURITUS; QT INTERVAL; SUSPENSION; TABLET; TORSADE DES POINTES; TRAVEL;

PLASMODIUM FALCIPARUM;

EID: 0030704617     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1080/00034983.1997.11813213     Document Type: Article

References (30)

1. BAUDON, D., BERNARD, J., MOULIAT PELIAT, J. P., MARTET, G., SARROUY, J., TOUZE, J. E., SPIEGEL, A., LANTRADE, P. & PICQ, J. J. (1992). Efficacy of a radical cure by halofantrine to prevent falciparum malaria on return from malarious areas. Annales de la Société Belge Médecine Tropicale, 72, 263-270.
2. BOUDRAUD, O., BASCO, K., GILLOTIN, F., GIMENEZ, O., RAMILIARISOA, B., GENISSEL, B., BOUVET, E., FARINOTTI, R., LE BRAS, J. & COULAUD, J. (1994). Clinical efficacy and pharmacokinetics of micronized halofantrine for the treatment of acute uncomplicated falciparum malaria in non immune patients. American Journal of Tropical Medicine and Hygiene, 51, 204-213.
3. BRYSON, M. & GOA, K. L. (1992). Halofantrine: a review of its antimalarial activity, pharmacokinetic properties and therapeutic potential. Drugs, 43, 236-258.
4. CASTOT, A., RAPOPORT, P. & LE COZ, P. (1993). Prolonged QT interval with halofantrine. Lancet, i, 1541.
5. COSGRIFF, T. M., BOUDREAU, E. F., PAMPLIN, C. L., DOBERSTYN, E. B., DESJARDIN, R. E. & CANFIELD, C. J. (1982). Evaluation of the antimalarial activity of the phenanthrene methanol halofantrine (WR 171,669). American Journal of Tropical Medicine and Hygiene, 31, 1075-1079.
6. COULAUD, J. P., LE BRAS, J., MATHERON, S., MORINIERE, B., SAIMOT, A. G. & ROSSIGNOL, J. F. (1986). Treatment of imported cases of falciparum malaria with halofantrine. Transactions of the Royal Society of Tropical Medicine and Hygiene, 80, 615-616.
7. FOURCADE, L., DE PINA, J. J., MOUSTAFGHIR, A., CUGUGLIERE, C., RAULT, J. P., VAN DE WALLE, J. P. & TOUZE, J. E. (1996). Choc anaphylactique à l'halofantrine. Médecine Tropicale, 56 (Suppl.), 61.
8. FREEDMAN, R. A. & STEINBERG, J. S. (1991). Selective prolongation of QRS late potentials by sodium channel blocking antiarrythmic drugs: relation to slowing of ventricular tachycardia. Journal of the American College of Cardiology, 17, 1017-1025.
9. GILLESPIE, S. H., MSAKI, E. P., RAMSAY, A., NGOWI, F. I. & FOX, R. (1993). A new micronized formulation of halofantrine hydrochloride in the treament of acute Plasmodium falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 87, 467-469.
10. HALLWOOD, P. M., HORTON, R. J., O'SULLIVAN, K. M. & PARR, S. N. (1989). Halofantrine and pruritus. Lancet, i, 397-398.
11. HORTON, R. J. & PARR, S. N. (1989). Halofantrine: an overview of efficacy and safety. Parasitology Today, 5 (Suppl.), 65-79.
12. JAMES, T. N., FROGATT, P. & ATKINSON, W. J. (1978). Observations on the pathophysiology of the long QT syndromes with special reference to the neuropathology of the heart. Circulation, 57, 1221-1231.
13. KARBWANG, J. & NA BANGCHANG, K. (1994). Clinical pharmacokinetics of halofantrine. Clinical Pharmacokinetics, 27, 104-119.
14. MILTON, K. A., EDWARDS, G., WARD, S. A., ORME, M. L. & BRECKENRIDGE, A. M. (1989). Pharmacokinetics of halofantrine in man: effects of food and dose size. British Journal of Clinical Pharmacology, 28, 71-77.
15. MOJON, M., WALLON, M., GRAVEY, A., PEAUD, P. Y., SARTRE, J. & PEYRON, F. (1994). Intravascular haemolysis following halofantrine intake. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88, 91.
16. MONLUN, E., PILLET, P., COCHARD, J. F. & LE BRAS, M. (1993). Prolonged QT interval with halofantrine. Lancet, i, 1541-1542.
17. NOSTEN, F., TER KUILE, F. O., LUXEMBURGER, C., WOODROW, C., KYLE, D. E., CHONGSUPHAJAISIDDHI, T. & WHITE, N. J. (1993). Cardiac effects of antimalarial treatment with halofantrine. Lancet, i, 1054-1056.
18. ROBLOT, F., BECQ-GIRAUDON, B., ROUÉ, R., LITAUDON, M. & BREUN, J. P. (1990). Crise convulsive au cours d'un traitement par halofantrine. Bulletin de la Société Française Jc Parasitologie, 8 (Suppl. 1), 445.
19. RODEN, D. M., THOMPSON, K. A., HOFFMAN, B. F. & WOOSLEY, R. (1986). Clinical features and basic mechanisms of quinidine-induced arrythmias. Journal of the American College of Cardiology, 8 (Suppl. A), A73-A78.
20. SOWUNMI, A., WALKER, O. & SALAKO, L. A. (1989). Pruritus and antimalarial drugs in Africans. Lancet, ii, 213.
21. TER KUILE, F. O., DOLAN, G., NOSTEN, F., EDSTEIN, M. D., LUXEMBURGER, C., PHAIPUN, L., CHONGSUPHAJAISIDDHI, T., WEBSTER, H. K. & WHITE, N. J. (1993). Halofantrine versus mefloquine in treatment of multidrug-rcsistant falciparum malaria. Lancet, i, 1044-1049.
22. TOBE, J. M., DE LANGEN, D. J. & MARGREET, D. (1992). Late potentials in a bradycardia-dependent long QT syndrome associated with sudden death during sleep. Journal of the American College of Cardiology, 19, 541-549.
23. TOUZE, J. E., DEHARO, J. C., IMBERT, P., FOURCADE, L., VAN DE WALLE, J. P. & DJIANE, P. (1994). Potentiels tardifs ventriculaires et traitement antimalarique par halofantrine. Presse Médicale, 23, 1450-1451.
24. TOUZE, J. E., BERNARD, J., KEUNDJIAN, A., IMBERT, P., CHAUDET, H. & DOURY, J. C. (1996). Electrocardiographic changes and halofantrine plasma level during acute falciparum malaria. American Journal of Tropical Medicine and Hygiene, 54, 225-228.
25. TOUZE, J. E., PERRET, J. L., NICOLAS, X., BERNARD, J., KEUNDJIAN, A., SOARES, J. M. & DOURY, J. C. (1997). Efficacy of low-dose halofantrine for second treatment for uncomplicated falciparum malaria. Lancet, 349, 255-256.
26. VACHON, F., FAJAC, J., GACHOT, B., COULAUD, J. P. & CHARMOT, G. (1992). Halofantrine and acute vascular haemolysis. Lancet, ii, 909-910.
27. VINCENT, M. P., BECQUART, J. P., RECEVEUR, M. C., NORDOR, O. & LE BRAS, M. (1992). Sur dosage à l'halofantrine. Presse Médicale, 21, 131.
28. WILDLING, E., WINKLER, S., BRANDTS, C., JENNE, L., GRANINGER, W., WERNSDORFER, W. H., BIENZLE, U. & KREMSNER, P. G. (1993). Halofantrine sensitivity. Lancet, ii, 55.
29. WIRIMA, J., KHOROMANA, C., MOLYNEUX, M. E. & GILLES, H. M. (1988). Clinical trials with halofantrine hydrochloride in Malawi. Lancet, ii, 250-252.
30. WORLD HEALTH ORGANIZATION (1990). Severe and complicated falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84 (Suppl.), 1-65.