Iron binding capacity of didox (3,4-dihydroxybenzohydroxamic acid) and amidox (3,4-dihydroxybenzamidoxime) new inhibitors of the enzyme rebinucleotide reductase

Life Sciences

Volumn 61, Issue 22, 1997, Pages 2231-2237

  Fritzer Szekeres, Monika ^a   Novotny, Ladislav ^b   Vachalkova, Anna ^b   Findenig, Gabriele ^a   Elford, Howard L ^c   Szekeres, Thomas ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b CANCER RESEARCH INSTITUTE   (Slovakia)

^c Molecules for Health Inc   (United States)

Author keywords

Cancer chemotherapy; Erythroleukemic K562 cell line; Iron complexing agents; Iron metabolism; Leukemia cells L1210; Ribonucleotide reductase (EC 1.17.4.1); Ribonucleotide reductase inhibitors

Indexed keywords

3,4 DIHYDROXYBENZOHYDROXAMIC ACID; AMIDOX; ANTINEOPLASTIC AGENT; FLUDARABINE; GEMCITABINE; HYDROXYUREA; IRON COMPLEX; OXIDOREDUCTASE INHIBITOR; RIBONUCLEOTIDE REDUCTASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN K 562; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IRON BINDING CAPACITY; IRON KINETICS; LEUKEMIA L 1210;

EID: 0030704299     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)00925-9     Document Type: Article

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