Autoactivity of A5 neurons: Role of subthreshold oscillations and persistent Na+ current

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 5 42-5, 1997, Pages

  Huangfu, Donghai ^a   Guyenet, Patrice G ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

A5 noradrenergic cells; Autoactivity; Autonomic regulations; Locus ceruleus; Persistent sodium current; Sympathetic tone

Indexed keywords

SODIUM; TETRODOTOXIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREATHING; ELECTROPHYSIOLOGY; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; LOCUS CERULEUS; MEMBRANE CURRENT; MEMBRANE POTENTIAL; NERVE CELL; NEWBORN; NOCICEPTION; NONHUMAN; OSCILLATION; PONS; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SYMPATHETIC TONE; THALAMUS VENTRAL NUCLEUS;

EID: 0030701886     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.5.h2280     Document Type: Article

References (10)

1. Burnett, A., and G. F. Gebhart. Characterization of descending modulation of nociception from the A5 cell group. Brain Res. 546: 271-281, 1991.
2. Byrum, C. E., and P. G. Guyenet. Afferent and efferent connections of the A5 noradrenergic cell group in the rat. J. Comp. Neural. 261:529-542, 1987.
3. Grill, W. E. Persistent sodium current in mammalian central neurons. Anna. Rev. Physiol. 58:349-362, 1996.
4. Edwards, F. A., A. Konnerth, B. Sakmann, and T. A. Takahashi. A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflügers Arch. 414:600-612, 1989.
5. Grace, A. A., and S.-P. Onn. Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. J. Neurosci. 9: 3463-3481, 1989.
6. Guyenet, P. G., N. Koshiya, D. Huangfu, A. J. M. Verberne, and T. A. Riley. Central respiratory control of A5 and A6 pontine noradrenergic neurons. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33): R1035-R1044, 1993.
7. 2-Adrenergic autoreceptors in A5 and A6 neurons of neonate rats. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H2290-H2295, 1997.
8. Huangfu, D., L. J. Hwang, T. A. Riley, and P. G. Guyenet. Splanchnic nerve response to A5-area stimulation in rats. Am. J. Physiol. 263 (Regulatory Integrative Comp. Physiol. 32): R437-R446, 1992.
9. Huangfu, D., N. Koshiya, and P. G. Guyenet. A5 noradrenergic unit activity and sympathetic nerve discharge in rats. Am. J. Physiol. 261 (Regulatory Integrative Comp. Physiol. 30): R393-R402, 1991.
10. Jansen, A. S. P., X. V. Nguyen, V. Karpitskiy, T. C. Mettenleiter, and A. D. Loewy. Central command neurons of the sympathetic nervous system: basis of the fight or flight response. Science 270: 644-646, 1995.