-
1
-
-
77956796530
-
Angiotensin / Renin Modulators
-
Bristol, J.A., Ed.; Academic Press : Amsterdam
-
Greenlee, W.J.; Siegl, P.K.S. Angiotensin / Renin Modulators. In Annual reports of Medicinal Chemistry; Bristol, J.A., Ed.; Academic Press : Amsterdam, 1992; Vol. 27, pp 59-68; 1991; Vol. 26, pp 63-72.
-
(1992)
Annual Reports of Medicinal Chemistry
, vol.27
, pp. 59-68
-
-
Greenlee, W.J.1
Siegl, P.K.S.2
-
2
-
-
77956796530
-
-
Greenlee, W.J.; Siegl, P.K.S. Angiotensin / Renin Modulators. In Annual reports of Medicinal Chemistry; Bristol, J.A., Ed.; Academic Press : Amsterdam, 1992; Vol. 27, pp 59-68; 1991; Vol. 26, pp 63-72.
-
(1991)
Annual Reports of Medicinal Chemistry
, vol.26
, pp. 63-72
-
-
-
3
-
-
85012573934
-
Antihypertensive Agents
-
Bristol, J.A., Ed.; Academic Press : Amsterdam
-
(b) Petrillo, E.W.; Trippodo, N.C.; De Forrest, J.M. Antihypertensive Agents. In Annual Reports of Medicinal Chemistry; Bristol, J.A., Ed.; Academic Press : Amsterdam, 1990; Vol. 25; pp 51-60.
-
(1990)
Annual Reports of Medicinal Chemistry
, vol.25
, pp. 51-60
-
-
Petrillo, E.W.1
Trippodo, N.C.2
De Forrest, J.M.3
-
4
-
-
0026078602
-
Nonpeptide Angiotension II receptor Antagoists
-
Timmermans, P.B.M.W.M.; Wong, P.C.; Chiu, A.T.; Herblin, W.F. Nonpeptide Angiotension II receptor Antagoists. Trends Pharmacol. Sci. 1991, 12, 55-62.
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 55-62
-
-
Timmermans, P.B.M.W.M.1
Wong, P.C.2
Chiu, A.T.3
Herblin, W.F.4
-
7
-
-
0026516486
-
The Discovery of DuP 753, a Potent, Orally Active Nonpeptide Angiotensin II Receptor Antagonist
-
(a) Duncia, J.V.; Carini, D.J.; Chiu, A.T.; Johnson, A.L.; Price, W.A.; Wong, P.C.; Wexler, R.R.; Timmermans, P.B.M.W.M. The Discovery of DuP 753, a Potent, Orally Active Nonpeptide Angiotensin II Receptor Antagonist Med. Res. Rev. 1992, 12, 149-191.
-
(1992)
Med. Res. Rev.
, vol.12
, pp. 149-191
-
-
Duncia, J.V.1
Carini, D.J.2
Chiu, A.T.3
Johnson, A.L.4
Price, W.A.5
Wong, P.C.6
Wexler, R.R.7
Timmermans, P.B.M.W.M.8
-
8
-
-
0025805993
-
DuP 753 : 2-n-Butyl-4-chloro-5-(hydroxymethyl)-1-[2′-(1H-tetrazol-5-yl)-biphenyl-4- yl]-methyl-imidazole Potassium Salt
-
(b) Duncia, J.V.; Carini, D.J., Chiu, A.T.; Pierce, M.E.; Price, W.A.; Smith, R.D.; Wells, G.J.; Wong, P.C.; Wexler, R.R.; Johnson, A.L.; Timmermans, P.B.M.W.M. DuP 753 : 2-n-Butyl-4-chloro-5-(hydroxymethyl)-1-[2′-(1H-tetrazol-5-yl)-biphenyl-4- yl]-methyl]-imidazole Potassium Salt Drugs Future 1991, 16, 305-309.
-
(1991)
Drugs Future
, vol.16
, pp. 305-309
-
-
Duncia, J.V.1
Carini, D.J.2
Chiu, A.T.3
Pierce, M.E.4
Price, W.A.5
Smith, R.D.6
Wells, G.J.7
Wong, P.C.8
Wexler, R.R.9
Johnson, A.L.10
Timmermans, P.B.M.W.M.11
-
9
-
-
0026050837
-
Nonpeptide Angiotensin II receptor Antagonists : The discovery of a series of N-(Biphenylmethyl)imidazole as Potent OrallyActive Antihypertensive
-
(c) carini, D.J.; Duncia, J.V.; Aldrich, P.E.; Chiu, A.T.; Johnson, A.L.; Pierce, M.E.; Price, W.A.; Santella, J.B.; Wells, G.J.; Wexler, R.R.; Wong, P.C.; Yoo, S.E.; Timmermans, P.B.M.W.M. Nonpeptide Angiotensin II receptor Antagonists : The discovery of a series of N-(Biphenylmethyl)imidazole as Potent OrallyActive Antihypertensive. J. Med. Chem. 1991, 34, 2525-2547.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 2525-2547
-
-
Carini, D.J.1
Duncia, J.V.2
Aldrich, P.E.3
Chiu, A.T.4
Johnson, A.L.5
Pierce, M.E.6
Price, W.A.7
Santella, J.B.8
Wells, G.J.9
Wexler, R.R.10
Wong, P.C.11
Yoo, S.E.12
Timmermans, P.B.M.W.M.13
-
10
-
-
0025265568
-
The Discovery of Potent Nonpeptide Angiotensin II receptor Antagonists : A New Class of Potent Antihypertensive
-
(d) Duncia, J.V.; Chiu, A.T.; carini, D.J.; Gregory, G.B.; Johnson, A.L.; Price, W.A.; Wells, G.J.; Wong, P.C.; Calabrese, J.C.; Timmermans, P.B.M.W.M. The Discovery of Potent Nonpeptide Angiotensin II receptor Antagonists : A New Class of Potent Antihypertensive. J. Med. Chem. 1990, 33, 1312-1329.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 1312-1329
-
-
Duncia, J.V.1
Chiu, A.T.2
Carini, D.J.3
Gregory, G.B.4
Johnson, A.L.5
Price, W.A.6
Wells, G.J.7
Wong, P.C.8
Calabrese, J.C.9
Timmermans, P.B.M.W.M.10
-
11
-
-
0025341823
-
Nonpeptide Angiotensin II Receptor Antagonists : N-[(Benzyloxy)-benzyl]imidazoles and Related Compounds as Potent Antihypertensive
-
(e) carini, D.J.; Duncia, J.V.; Johnson, A.L.; Chiu, A.T.; Price, W.A.; Wong, P.C.; Timmermans, P.B.M.W.M. Nonpeptide Angiotensin II Receptor Antagonists : N-[(Benzyloxy)-benzyl]imidazoles and Related Compounds as Potent Antihypertensive. J. Med. Chem. 1990, 33, 1330-1336.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 1330-1336
-
-
Carini, D.J.1
Duncia, J.V.2
Johnson, A.L.3
Chiu, A.T.4
Price, W.A.5
Wong, P.C.6
Timmermans, P.B.M.W.M.7
-
12
-
-
0026000304
-
Orally Active Imidazo[4,5-b]pyridine-Based Angiotensin II Receptor Antagonists
-
Mantlo, N.B.; Chakravarty, P.K.; Ondeyka. D.L.; Siegl, P.K.S.; Chang, R.S.; Lotti, V.J.; Faust, K.A.; Chen, T.-B.; Schorn, T.W.; Sweet, C.S.; Emmert, S.E.; Patchett, A.A.; Greenlee, W.J. Potent, Orally Active Imidazo[4,5-b]pyridine-Based Angiotensin II Receptor Antagonists. J. Med. Chem. 1991, 34, 2919-2922.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 2919-2922
-
-
Mantlo, N.B.1
Chakravarty, P.K.2
Ondeyka, D.L.3
Siegl, P.K.S.4
Chang, R.S.5
Lotti, V.J.6
Faust, K.A.7
Chen, T.-B.8
Schorn, T.W.9
Sweet, C.S.10
Emmert, S.E.11
Patchett, A.A.12
Potent, G.W.J.13
-
13
-
-
0027757114
-
-
Dhanoa, D.S.; Bagley, S.W.; Chang, R.S.R.; Lotti, V.J.; Chen, T.B.; Kivlighn, S.D.; Zingoro, G.J.; Siegl, P.K.S.; Patchett, A.A.; Greenlee, W.J. J. Med. Chem. 1993, 36, 4230.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 4230
-
-
Dhanoa, D.S.1
Bagley, S.W.2
Chang, R.S.R.3
Lotti, V.J.4
Chen, T.B.5
Kivlighn, S.D.6
Zingoro, G.J.7
Siegl, P.K.S.8
Patchett, A.A.9
Greenlee, W.J.10
-
15
-
-
0026591413
-
-
El-Diwani, H.; Nakkadi, S.S.; Hishmat, O.H.; El-Shabrawi, D.A.; Mahmoud, S.S.; Pharmazie, 1992, 47, 178.
-
(1992)
Pharmazie
, vol.47
, pp. 178
-
-
El-Diwani, H.1
Nakkadi, S.S.2
Hishmat, O.H.3
El-Shabrawi, D.A.4
Mahmoud, S.S.5
-
16
-
-
5244266637
-
-
U.S. 3, 565, 912, 1971
-
Szmuszkovicz, J. : Anti-inflammatory 5-alkanoyl-2,3-bis(p-methoxyphenyl)indoles. U.S. 3, 565, 912, 1971; C.A. 74, 141532n (1971).
-
Anti-inflammatory 5-alkanoyl-2,3-bis(p-methoxyphenyl)indoles
-
-
Szmuszkovicz, J.1
-
17
-
-
5244252757
-
-
Szmuszkovicz, J. : Anti-inflammatory 5-alkanoyl-2,3-bis(p-methoxyphenyl)indoles. U.S. 3, 565, 912, 1971; C.A. 74, 141532n (1971).
-
(1971)
C.A.
, vol.74
-
-
-
19
-
-
5244238936
-
-
91972
-
Szmuszkovicz, J. : Anti-inflammatory 2,3-bis(p-methoxyphenyl)-indole-5-carboxylic acid derivatives. U.S. 3, 654, 308; C.A. 77, 34319r 91972).
-
C.A.
, vol.77
-
-
-
20
-
-
21844492105
-
-
El-Diwani, H.I.; Shmeiss, N.A.M.M.; Saleh, N.M.; Polish J. Chem., 1995, 69, 470.
-
(1995)
Polish J. Chem.
, vol.69
, pp. 470
-
-
El-Diwani, H.I.1
Shmeiss, N.A.M.M.2
Saleh, N.M.3
-
21
-
-
5244240766
-
-
Ger Offen. 2, 024, 966, 1970
-
Lundt, B.F. and Anderson, W. : Analgesic 3-(aminoalkoxy)indoles. Ger Offen. 2, 024, 966, 1970; C.A. 74, 53520d (1971).
-
Analgesic 3-(aminoalkoxy)indoles
-
-
Lundt, B.F.1
Anderson, W.2
-
22
-
-
6544280412
-
-
Lundt, B.F. and Anderson, W. : Analgesic 3-(aminoalkoxy)indoles. Ger Offen. 2, 024, 966, 1970; C.A. 74, 53520d (1971).
-
(1971)
C.A.
, vol.74
-
-
-
23
-
-
5244273030
-
-
Univ. Frankfurt, Ger.
-
Hans, J.T.; Karl, S. (Univ. Frankfurt, Ger.) Chem. Ber. 1958, 91, 2089-94.
-
(1958)
Chem. Ber.
, vol.91
, pp. 2089-2094
-
-
Hans, J.T.1
Karl, S.2
-
24
-
-
67249094291
-
-
Winter, C.A.; Risley, E.V.; Nuss, G.W. : Proc. Soc. Exp. Biol. Med. 1962, 111, 544; C.A. 59, 1143 (1963).
-
(1962)
Proc. Soc. Exp. Biol. Med.
, vol.111
, pp. 544
-
-
Winter, C.A.1
Risley, E.V.2
Nuss, G.W.3
-
25
-
-
67249094291
-
-
Winter, C.A.; Risley, E.V.; Nuss, G.W. : Proc. Soc. Exp. Biol. Med. 1962, 111, 544; C.A. 59, 1143 (1963).
-
(1963)
C.A.
, vol.59
, pp. 1143
-
-
-
26
-
-
0003633894
-
-
Iowa State University Press, Ames, Iowa
-
Snedecor, W.G.; Cochran, G.W. (eds), Statistical methods, Iowa State University Press, Ames, Iowa 1971.
-
(1971)
Statistical Methods
-
-
Snedecor, W.G.1
Cochran, G.W.2
-
27
-
-
70449138242
-
Series of potent analgesic d-2,2-diphenyl-3-methyl-4-mprpholino-butyl-pyrrolidine and realted basic amides. (II) comparative analgesic activity, acute toxicity and tolerance development in rats for R.875, morphine, pethidine and methadone
-
Jansen, P.A.J.; Jageneau, A.H. : "Series of potent analgesic d-2,2-diphenyl-3-methyl-4-mprpholino-butyl-pyrrolidine and realted basic amides. (II) comparative analgesic activity, acute toxicity and tolerance development in rats for R.875, morphine, pethidine and methadone", J. Pharm. Pharmac. 9, 381 (1957).
-
(1957)
J. Pharm. Pharmac.
, vol.9
, pp. 381
-
-
Jansen, P.A.J.1
Jageneau, A.H.2
-
28
-
-
0009573378
-
-
St Louis, C.V. Mosby Company
-
Jackson, D.E. : "Experimental Pharmacology", St Louis, C.V. Mosby Company, 1939, p 99. Jackson, D.E. : "Experimental Pharmacology", St Louis, C.V. Mosby Company, pp 99 (1939).
-
(1939)
Experimental Pharmacology
, pp. 99
-
-
Jackson, D.E.1
-
29
-
-
0009573378
-
-
St Louis, C.V. Mosby Company
-
Jackson, D.E. : "Experimental Pharmacology", St Louis, C.V. Mosby Company, 1939, p 99. Jackson, D.E. : "Experimental Pharmacology", St Louis, C.V. Mosby Company, pp 99 (1939).
-
(1939)
Experimental Pharmacology
, pp. 99
-
-
Jackson, D.E.1
|