α 2-adrenergic agonists. Use in chronic pain - A meta-analysis;Alpha-adrenozeptor-agonisten zur therapie chronischer schmerzen - Metaanalyse

Schmerz

Volumn 11, Issue 5, 1997, Pages 339-344

  Motsch, J ^a   Kamler, M ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

2 adrenergic agonists; Chronic pain; Neuropathic pain; Sympathetically maintained pain; Systemical administration of clonidine

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; CODEINE; IBUPROFEN; IMIPRAMINE; MORPHINE; PARACETAMOL; PLACEBO;

ANTINOCICEPTION; ARTICLE; CHRONIC PAIN; CLINICAL TRIAL; DIABETIC NEUROPATHY; DRUG EFFICACY; DRUG POTENTIATION; DRUG THERAPY; EPIDURAL DRUG ADMINISTRATION; HUMAN; HYPERALGESIA; LONG TERM CARE; LOW BACK PAIN; ORAL DRUG ADMINISTRATION; POSTHERPETIC NEURALGIA; THORAX PAIN; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0030700355     PISSN: 0932433X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004820050108     Document Type: Article

References (22)

1. Cannon III OR, Quyyumi AA, Mincemoyer R, Stine AM, Gracely RH, Smith WB, Geraci MF, Black BC, UhdeTW, Waclawiw MA, Mahrer K, Benjamin SB (1994) Imipramine in patients with chest pain despite normal coronary angiograms. N Engl J Med 330: 1114-1417
2. Carroll D, Jada A, King V, Wiffen P, Glynn C, McQuay H (1993) Single-dose, randomized, double-blind, double-dummy cross-over comparison of extradural and i.v. clonidine in chronic pain. BrJ Anaesth 71:665-669
3. Cavillo O, Ghignone M (1986) Presynaptic effect of clonidine on unmyelinated afferent fibers in the spinal cord of the cat. Neurosci Lett 64: 335-339
4. Coombs DW, Saunders RS, Fratkin JD, Jensen LE, Murphy CA (1986) Continuous intrathecal hydromorphone and clonidine for in tractable cancer pain. J Neurosurg 64: 890-894
5. Davis KD, Treede RD, Raja SN, Meyer RA, Campbell JN (1991) Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain 47: 309-317
6. Devor M (1983) Nerve pathophysiology and mechanisms of pain in causalgia. J Auton Nerv Syst 7: 371-384
7. Glynn CJ, Teddy PJ, Jamous MA, Moore RA, Lloyd JW (1986) Role of spinal noradrenergic system in transmission of pain in patients with spinal cord injury. Lancet 2: 1249-1250
8. Goldstein JA (1983) Clonidine as analgesic. Biol Psychiatry 18: 1339-1340
9. Jurna I, Motsch J (1993) Nichtanalgetika: Antidepressiva, Antikonvulsiva, Neurolep tika, Tranquillantien und zentrale Muskelrelaxantien, Clonidin, Cortison. In: Zenz M, Jurna I (Hrsg) Lehrbuch der Schmerztherapie. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 163-164
10. Langer SZ, Cavero I, Massingham R (1980) Recent developments in noradrenergic neurotransmission and its relevance to the mechanism of action of certain antihypertensive agents. Hypertension 2: 372-382
11. Max MB, Schafer SC, Culnane M, Dubner R, Gracely RH (1988) Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo. Clin Pharmacol Ther 43: 363-371
12. Michel MC, Insel PA (1989) Are there multipie imidazoline binding sites? Trends Pharmacol Sci 10:342-344
13. Paalzow L (1974) Analgesia produced by clonidine in mice and rats. J Pharm Pharmacol 26:551-563
14. Petros AJ, Bowen Wright RM (1987) Epidural and oral clonidine in domiciliary control of deafferentation pain. Lancet 1:1034
15. Sagen J. Proudfit HK (1985) Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata. Brain Res 331: 285-293
16. Sandgren JE, McPhee MS, Greenberger NJ (1984) Narcotic bowel syndrome treated with clonidine. Resolution of abdominal pain and intestinal pseudo-obstruction. Ann Intern Med 101: 331-334
17. Tamsen A, Gordh T (1984) Epidural clonidine produces analgesia. Lancet II: 231-232
18. Tan YM, Croese J (1986) Clonidine and diabetic patients with leg pains. Ann Intern Med 105: 633-634
19. Uhde TW, Post RM, Siever LJ, Buchsbaum MS (1980) Clonidine and psychophysical pain. Lancet II: 1375
20. Wilcox GL, Carlsson KH, Jochim A, Jurna I (1987) Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord. Brain Res 405: 84-93
21. Yaksh TL (1985) Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing. Pharmacol Biochem Behav 22: 845-858
22. Zeigler D, Lynch SA, Muir J, Bemjamin J, Max MB (1992) Transdermal clonidine versus placebo in painful diabetic neuropathy. Pain 48: 403-408