Yeast acetyl-CoA carboxylase is associated with the cytoplasmic surface of the endoplasmic reticulum

European Journal of Cell Biology

Volumn 74, Issue 4, 1997, Pages 399-406

  Ivessa, Andreas S ^a,b   Schneiter, Roger ^a   Kohlwein, Sepp D ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

Acetyl CoA carboxylase; Endoplasmic reticulum; Fatty acid synthesis; Nuclear pore complex; Subcellular localization

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; MEMBRANE ENZYME; PROTEINASE K;

ARTICLE; CATALYSIS; CELL FRACTIONATION; CELL NUCLEUS MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME LOCALIZATION; FATTY ACID SYNTHESIS; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOFLUORESCENCE TEST; NONHUMAN; PRIORITY JOURNAL; SOLUBILIZATION; YEAST CELL;

EID: 0030698668     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Al-Feel, W., S. S. Chirala, S. J. Wakil: Cloning of the yeast FAS3 gene and primary structure of yeast acetyl-CoA carboxylase. Proc. Natl. Acad. Sci. USA 89, 4534-4538 (1992).
2. Aris, J. P., G. Blobel: Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein. J. Cell Biol. 107, 17-31 (1988).
3. Aris, J. P., G. Blobel: Yeast nuclear envelope proteins cross react with an antibody against mammalian pore complex proteins. J. Cell Biol. 108, 2059-2067 (1989).
4. Basson, M. E., M. K. Thorsness, J. Finer-Moore, R. Stroud, J. Rine: Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis. Mol. Cell. Biol. 9, 3797-3808 (1988).
5. Caplan, A. J., M. G. Douglas: Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein. J. Cell Biol. 114, 609-621 (1991).
6. Chirala, S. S., Q. Zhong, W. Huang, W. Al-Feel: Analysis of FAS3/ACC regulatory region of Saccharomyces cerevisiae: identification of a functional UASINO and sequences responsible for fatty acid mediated repression. Nucleic Acids Res. 22, 412-418 (1994).
7. Cinti, D. L., L. Cook, M. N. Nagi, S. K. Suneja: The fatty acid chain elongation system of mammalian endoplasmic reticulum. Prog. Lipid Res. 31, 1-51 (1992).
8. Daum, G., P. C. Böhni, G. Schatz: Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J. Biol. Chem. 257, 13028-13033 (1982).
9. Davis, L. I.: The nuclear pore complex. Annu. Rev. Biochem. 64, 365-396 (1995).
10. Drubin, D. G., K. G. Miller, D. Botstein: Yeast actin-binding proteins: evidence for a role in morphogenesis. J. Cell Biol. 107, 2251-2561 (1988).
11. Goldberg, M. W., T. D. Allen: Structural and functional organization of the nuclear envelope. Curr. Opin. Cell Biol. 7, 301-309 (1995).
12. Hasslacher, M., A. S. Ivessa, F. Paltauf, S. D. Kohlwein: Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism. J. Biol. Chem. 268, 10946-10952 (1993).
13. Hori, T., N. Nakamura, H. Okuyama: Possible involvement of acetyl coenzyme A carboxylase as well as fatty acid synthetase in the temperature-controlled synthesis of fatty acids in Saccharomyces cerevisiae. J. Biochem. 101, 949-956 (1987).
14. Hurt, E. C., A. McDowall, T. Schimmang: Nucleolar and nuclear envelope proteins of the yeast Saccharomyces cerevisiae. Eur. J. Cell Biol. 46, 554-563 (1988).
15. Ito, H., Y. Fukada, K. Murata, A. Kimura: Transformation of intact cells with alkali cations. J. Bacteriol. 153, 163-168 (1983).
16. Kadowaki, T. S. Chen, M. Hitomi, E. Jacobs, C. Kumagai, S. Liang, R. Schneiter, D. Singleton, J. Wisniewska, A. M. Tartakoff: Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants. J. Cell Biol. 126, 649-659 (1994).
17. Kearsey, S. E.: Identification of a Saccharomyces cerevisiae gene closely related to FAS3 (acetyl-CoA carboxylase). DNA Seq. 4, 69-70 (1993).
18. Kleinschmidt, A. K., J. Moss, M. D. Lane: Acetyl coenzyme A carboxylase: filamentous nature of the animal enzymes. Science 166, 1276-1278 (1969).
19. Kohlwein, S. D., G. Daum, R. Schneiten F. Paltauf: Phospholipids: synthesis, sorting, subcellular traffic - the yeast approach. Trends Cell Biol. 6, 260-266 (1996).
20. Deleted in proof.
21. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).
22. Lane, M. D., J. Moss, S. E. Polakis: Acetyl Coenzyme A Carboxylase. In: K. E. Ebner (ed): Subunit Enzymes, Biochemistry and Function. pp. 181-221. Marcel Dekker Inc. New York 1975
23. Lazarides, E., U. Lindberg: Actin is the naturally occurring inhibitor of deoxyribonuclease I. Proc. Natl. Acad. Sci. USA 71, 4742-4746 (1974).
24. Li, O., C. V. Heath, D. C. Amberg, T. Dockendorff, C. S. Copeland, M. Snyder, C. N. Cole: Mutation or deletion of the Saccharomyces cerevisiae RAT3/NUP133 gene causes temperature-dependent nuclear accumulation of poly(A)+ RNA and constitutive clustering of nuclear pore complexes. Mol. Biol. Cell 6, 401-417 (1995).
25. Lim, F., M. Rohde, C. P. Morris, J. C. Wallace: Pyruvate carboxylase in the yeast pyc mutant. Arch. Biochem. Biophys. 258, 259-264 (1987).
26. Lowry, O. H., N. J. Rosebrough, A. L. Farr, R. J. Randall: Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275 (1951).
27. Nothwehr, S. F., N. J. Bryant, T. H. Stevens: The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol. Cell. Biol. 16, 2700-2707 (1996).
28. Paltauf, F., S. D. Kohlwein, S. A. Henry: Regulation and Compartmentalization of Lipid Synthesis in Yeast. In: E. W. Jones, J. R. Pringle, J. R. Broach (eds): The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression. pp. 415-500. Cold Spring Harbor Laboratory Press. Cold Spring Harbor 1992.
29. Preuss, D., J. Mulholland, C. A. Kaiser, P. Orlean, C. Albright, M. D. Rose, P. W. Robbins, D. Botstein: Structure of the yeast endoplasmic reticulum: localization of ER proteins using immunofluorescence and immunoelectron microscopy. Yeast 7, 891-911 (1991).
30. Saitoh, S., K. Takahashi, K. Nabeshima, Y. Yamashita, Y. Nakaseko, A. Hirata, M. Yanagida: Aberrant mitosis in fission yeast mutants defective in fatty acid synthetase and acetyl CoA carboxylase. J. Cell Biol. 134, 949-961 (1996).
31. Schneiter, R., M. Hitomi, A. S. Ivessa, E. V. Fasch, S. D. Kohlwein, A. M. Tartakoff: A yeast acetyl-CoA carboxylase mutant links very long-chain fatty acid synthesis to structure and function of the nuclear membrane/pore complex. Mol. Cell. Biol. 16, 7161-7172 (1996).
32. Schneiter, R., S. D. Kohlwein: Organelle structure, function, and inheritance in yeast: a role for fatty acid synthesis? Cell 88, 431-434 (1997).
33. Schweizer, E., H. Boiling: A Saccharomyces cerevisiae mutant defective in saturated fatty acid biosynthesis. Proc. Nail. Acad. Sci. USA 67, 660-666 (1970).
34. Serrano, R.: Structure and function of proton translocating ATPase in plasma membranes of plants and fungi. Biochim. Biophys. Acta 947, 1-28 (1988).
35. Sherman, F., G. R. Fink, J. B. N. Hicks: Methods in Yeast Genetics: A Laboratory Course Manual. Cold Spring Harbor Laboratory. Cold Spring Harbor. New York 1986.
36. Strambio-de-Castillia, C., G. Blobel, M. P. Rout: Isolation and characterization of nuclear envelopes from the yeast Saccharomyces. J. Cell Biol. 131, 19-31 (1995).
37. Toke, D. A., C. E. Martin: Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae. J. Biol. Chem. 271, 18413-18422 (1996).
38. Wintersberger, U., C. Kühne, A. Karwan: Scp160p, a new yeast protein associated with the nuclear membrane and the endoplasmic reticulum, is necessary for maintenance of exact ploidy. Yeast 11, 929-944 (1995).
39. Witters, L. A., T. D. Watts: Yeast acetyl-CoA carboxylase: in vitro phosphorylation by mammalian and yeast protein kinases. Biochem. Biophys. Res. Commun. 169, 369-376 (1990).
40. Wright, R., M. Basson, L. D'Ari, J. Rine: Increased amounts of HMG-CoA reductase induce "karmellae": a proliferation of stacked membrane pairs surrounding the yeast nucleus. J. Cell Biol. 107, 101-114 (1988).
41. Yuan, Y. L., S. Fields: Properties of the DNA-binding domain of the Saccharomyces cerevisiae STE12 protein. Mol. Cell. Biol. 11, 5910-5918 (1991).