Use of CoMFA in validating the conformation used in designing 4-(1H- benzimidazole-2-carbonyl)piperidines with H1/NK1 receptor antagonist activity

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 22, 1997, Pages 2825-2830

  Vaz, Roy J ^a   Maynard, George D ^a   Kudlacz, Elizabeth M ^a   Bratton, Larry D ^a   Kane, John M ^a   Shatzer, Scott A ^a   Knippenberg, Robert W ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1H BENZIMIDAZOLE 2 CARBONYL)PIPERIDINE; HISTAMINE H1 RECEPTOR ANTAGONIST; NEUROKININ 1 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG DESIGN; DRUG RECEPTOR BINDING;

EID: 0030697345     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10098-1     Document Type: Article

References (14)

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