Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis

Development

Volumn 124, Issue 22, 1997, Pages 4627-4638

  Iida, Kiyoshi ^a   Koseki, Haruhiko ^b,e   Kakinuma, Hideaki ^a   Kato, Naoko ^a   Mizutani Koseki, Yoko ^b,e   Ohuchi, Hideyo ^c   Yoshioka, Hidefumi ^c   Noji, Sumihare ^c   Kawamura, Koichi ^a   Kataoka, Yuki ^d   Ueno, Fukuko ^d   Taniguchi, Masaru ^b,e   Yoshida, Nobuaki ^d   Sugiyama, Toshihiro ^a   Miura, Naoyuki ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

^e CREST

Author keywords

Aortic arch; DiGeorge syndrome; Interruption; Knockout mouse; MFH 1; Neural crest cells; Skeletogenesis; Winged helix proteins

Indexed keywords

TRANSCRIPTION FACTOR;

AORTA; AORTA ARCH; AORTA ARCH INTERRUPTION; ARTICLE; BONE DEVELOPMENT; CARTILAGINOUS TISSUE; EMBRYO; EMBRYO DEVELOPMENT; KIDNEY; MESENCHYME; MESENCHYME CELL; MOUSE; MUTAGENESIS; NEURAL CREST; NEURAL CREST CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AORTA, THORACIC; BASE SEQUENCE; BONE AND BONES; DIGEORGE SYNDROME; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; HUMANS; IN SITU HYBRIDIZATION; MALE; MESODERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; NEURAL CREST; PHENOTYPE; PREGNANCY; TRANSCRIPTION FACTORS;

EID: 0030696897     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Ang, S-L. and Rossant, J. (1994). HNF-3β is essential for node and notochord formation in mouse development. Cell 78, 561-574.
2. Brannan, C.I., Perkins, A.S., Vogel, K.S., Ratner, N., Nordlund, M.L., Reid, S.W., Buchberg, A.M., Jenkins, N.A., Parada, L.F. and Copeland, N.G. (1994). Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev. 8, 1019-1029.
3. Celoria, G.C. and Patton, R.B. (1959). Congenital absence of the aortic arch. Am. Heart J. 58, 407-413.
4. Christ, B. and Wilting, J. (1992). From somites to vertebral column. Ann. Anat. 174, 23-32.
5. Couly, G. F., Coltey, P. M. and Le Douarin, N. M. (1993) The triple origin of skull in higher vertebrates: a study in quail-chick chimeras. Development 117, 409-429.
6. Franz, T. (1989). Persistent truncus arteriosus in the Splotch mutant mouse. Anat. Embryol. 180, 457-464.
7. Goldmuntz, E. and Emanuel, B.S. (1997). Genetic disorders of cardiac morphogenesis: The DiGeorgc and velocardiofacial syndromes. Circ. Res. 80, 437-443.
8. Hall, B. K. and Miyake, T. (1992). The membrane skeleton: the role of cell condensation in vertebrate skeletogenesis. Anat Embryol 186, 107-124.
9. Hatini, V., Huh, S.O., Herzlinger, D., Soares, V.C. and Lai. E. (1996) Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of winged helix transcription factor BF-2. Genes Dev. 10, 1467-1478.
10. Kaestner, K.H., Bleckmann, S.C., Monaghan, P., Schlondorff, J., Mincheva, A., Lichter, P. and Schutz, G. (1996). Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development. Development 122, 1751-1758.
11. Kaufmann, E. and Knochel, W. (1996). Five years on the wings of fork head. Mech. Dev. 57, 3-20.
12. Kessel, M. and Gruss, P. (1991). Homeotic transformation of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 67, 89-104.
13. Kirby, M.L. and Waldo, K.L. (1990). Role of neural crest in congenital heart disease. Circulation 82, 332-340.
14. Kirby, M.L. and Waldo, K.L. (1995). Neural crest and cardiovascular patterning. Circ. Res 77, 211-215.
15. Kurihara, Y., Kurihara, H., Oda, H., Maemura, K., Nagai, R., Ishikawa, T. and Yazaki, Y. (1995). Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J. Clin. Invest. 96, 293-300.
16. Kurihara, Y., Kurihara, H., Suzuki, H., Kodama, T., Maemura, K., Nagai, R., Oda, H., Kuwaki, T., Cao, W-H., Kamada, N., Jishage, K., Ouchi, Y., Azuma, S., Toyoda, Y., Ishikawa, T., Kumada, M. and Yazaki, Y. (1994). Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 368, 703-710.
17. Lai, E., Clark, K.L., Burley, S.K. and Darnell, J.E., Jr. (1993) Hepatocyte nuclear factor 3/fork head or 'winged helix" proteins: A family of transcription factors of diverse biologic function. Proc. Natl. Acad. Sci. USA 90, 10421-10423.
18. Mendelsohn, C., Lohnes, D., Decimo, D., Lufkin, T., LeMeur, M., Chambon, P. and Mark, M. (1994). Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120, 2749-2771.
19. van Mierop, L.H.S. and Kutsche, L.M. (1984). Interruption of the aortic arch and coarctation of the aorta: Pathogenetic relations. Am. J. Cardiol. 54, 829-834.
20. Miura, N., Iida, K., Kakinuma, H., Yang, X-L. and Sugiyama, T. (1997). Isolation of the mouse (MFH-1) and human (FKHL14) Mesenchyme Fork Head-1 genes reveals conservation of their gene and protein structures. Genomics 41, 489-492.
21. Miura, N., Wanaka, A., Tohyama, M. and Tanaka, K. (1993) MFH-1. a new member of the fork head domain family, is expressed in developing mesenchyme. FEBS Lett. 326, 171-176.
22. Mo, R., Freer, A. M., Zinyk, D. L., Crackower, M. A., Michaud, J., Heng, H. H.-Q., Chik, K. W., Shi, X. M., Tsui, L.-C., Cheng, S. H., Joyner, A. L. and Hui, C.-c. (1997). Specific and redundant functions of Gl2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124, 113-123.
23. Moller, J.H. and Edwards, J.E. (1965). Interruption of aortic arch. Am. J. Roentgenol. 95, 557-572.
24. Nehls, M., Pfeifer, D., Schorpp, M., Hedrich, H. and Boehm, T. (1994) New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature 372, 103-107.
25. Noden, D. M. (1983). The role of the neural crest in patterning of avian skeletal, connective, and muscle tissues. Dev. Biol. 96, 144-165.
26. Olson, E.N. and Srivastava, D. (1996). Molecular pathways controlling heart development. Science 272, 671-676.
27. Osumi-Yamashita, N., Ninomiya, Y., Doi, H. and Eto, K. (1994) The contribution of both forebrain and midbrain crest cells to the mesenchyme in the frontonasal mass of mouse embryos. Dev. Biol. 164, 409-419.
28. Sasaki, H. and Hogan, B. L. M. (1993). Differential expression of multiple forkhead related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118, 47-59.
29. Tanaka, T., Akira, S., Yoshida, K., Umemoto, M., Yoneda, Y., Shirafuji, N., Fujiwara, H., Suematsu, S., Yoshida, N. and Kishimoto, T. (1995). Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell 80, 353-361.
30. Xuan, S., Baptista, C.A., Balas, G., Tao, W., Soares, V.C. and Lai, E. (1995). Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 14, 1141-1152.
31. Weigel, D., Jurgens, G., Kuttner, F., Seifert, E. and Jackle, H. (1989). The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell 57, 646-658.
32. Weinstein, D.C., Ruizi Altaba, A., Chen, W.S., Hoodles, P., Prezioso, Jassel, T.M. and Darnell, Jr., J.D. (1994). The winged-helix transcription factor HNF-3 is required for notochord development in the mouse embryo. Cell 78, 575-588.
33. Wilkinson, D.G. (1992). Whole mount in situ hybridization of vertebrate embryos. In In situ Hybridization. (ed. D. G. Wilkinson), pp. 75-83. Oxford: IRI. Press
34. Wilson. D.I., Burn, J., Scambler, P. and Goodship, J. (1993) DiGeorge syndrome: part of CATCH22. J. Med. Genet. 30, 852-856.
35. Winner, G. E., Hargett, L. and Hogan, L. M. (1997). The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Genes Dev. 11, 926-940.