Effects of NKH477, a forskolin derivative, and dibutyryl-cyclic AMP on adrenal catecholamine release in response to splanchnic nerve stimulation, acetylcholine, DMPP and muscarine in anesthetized dogs

Fundamental and Clinical Pharmacology

Volumn 11, Issue 6, 1997, Pages 512-518

  Koshika, T ^a   Nagayama, T ^a   Iizuka, Y ^a   Kimura, T ^b   Satoh, S ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b NIPPON DENTAL UNIVERSITY   (Japan)

Author keywords

Acetylcholine; Adrenal catecholamines; Dibutyryl cyclic AMP; NKH477; Splanchmic nerve stimulation

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; 6 (3 DIMETHYLAMINOPROPIONYL)FORSKOLIN; ACETYLCHOLINE; BUCLADESINE; FORSKOLIN DERIVATIVE; MUSCARINE; MUSCARINIC RECEPTOR; NICOTINIC RECEPTOR;

ADRENAL GLAND; ANIMAL EXPERIMENT; ARTICLE; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DOG; FEMALE; INTRAARTERIAL DRUG ADMINISTRATION; MALE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; SPLANCHNIC NERVE;

EID: 0030696071     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.1997.tb00855.x     Document Type: Article

References (32)

1. Anderson K, Robinson PJ, Marley PD. Cholinoceptor regulation of cyclic AMP levels in bovine adrenal medullary cells. Br J Pharmacol 1992; 106:360-6
2. +. Biochem Biophys Acta 1985;846:388-93
3. Cheek TR, Burgoyne RD. Cyclic AMP inhibits both nicotineinduced actin disassembly and catecholamine secretion from bovine adrenal chromaffin cells. J Biol Chem 1987; 262:11663-6
4. Douglas WW, Poisner AM. Preferential release of adrenaline from the adrenal medulla by muscarine and pilocarpine. Nature 1965;208:1102-3
5. Douglas WW, Kanno T, Sampson SR. Effects of acetylcholine and other medullary secretagogues and antagonists on the membrane potential of adrenal chromaffin cells: an analysis employing techniques of tissue culture. J Physiol (Lond) 1967;191:107-20
6. 2+ channels in bovine adrenal chromaffin cells. Pflugers Arch 1992;420: 61-71
7. Dubin AE, Rathouz MM, Mapp KS, Berg DK. Cyclic AMP and the nicotinic response of bovine adrenal chromaffin cells. Brain Res 1992;586:344-7
8. Feldberg W, Minz B, Tsudimura H. The mechanism of the nervous discharge of adrenaline. J Physiol (Lond) 1934;81: 286-304
9. Fujita A, Takahira T, Hosono M, Nakamura K. Improvement of drug-induced cardiac failure by NKH477, a novel forskolin derivative, in the dog heart-lung preparation. Jpn J Pharmacol 1992;58:375-81
10. Garcia AG, Sala F, Reig JA, Garcia L. Dihydropyridine BAYK-8644 activates chromaffin cell calcium channels. Nature 1984;309:69-71
11. Häggblad J, Eriksson H, Hedlund B, Heilbronn E. Forskolin blocks carbachol-mediated ion-permeability of chick myotube nicotinic receptors and inhibits binding of 3H-phencyclidine to Torpedo microsac nicotinic receptors. Naunyn Schmiedebergs Arch Pharmacol 1987;336:381-6
12. Harish OE, Kao LS, Raffaniello R, Wakade AR, Shneider AS. Calcium dependence of muscarinic receptor-mediated catecholamine secretion from the perfused adrenal medulla. J Neurochem 1987;48:1730-5
13. Higgins LS, Berg DK. Cyclic AMP-dependent mechanism regulates acetylcholine receptor function on bovine adrenal chromaffin cells and discriminates between new and old receptors. J Cell Biol 1988;107:1157-65
14. Hosono M, Takahira T, Fujita A, Fujihara R, Ishizuka O, Tatee T, Nakamura K. Cardiovascular and adenylate cyclase stimulant properties of NKH477, a novel water-soluble forskolin derivative. J Cardiovasc Pharmacol 1992;19:625-34
15. Ishizuka O, Hosono M, Nakamura K. Profile of cardiovascular effects of NKH477, a novel forskolin derivative, assessed in isolated, blood-perfused dog heart preparations: comparison with isoproterenol. J Cardiovasc Pharmacol 1992;20:261-7
16. Keogh R, Marley PD. Regulation of cyclic AMP levels by calcium in bovine adrenal medullary cells. J Neurochem 1991; 57:1721-8
17. Kidokoro Y, Miyazaki S, Ozawa S. Acetylcholine-induced membrane depolarization and potential fluctuations in the rat adrenal chromaffin cell. J Physiol (Lond) 1982;324: 203-20
18. Kimura T, Katoh M, Satoh S. Inhibition by opioid agonists and enhancement by antagonists of the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation: evidence for the functional role of opioid receptors. J Pharmacol Exp Ther 1988;244:1098-102
19. Kimura T, Shimamura T, Satoh S. Effects of pirenzepine and hexamethonium on adrenal catecholamine release in responses to endogenous and exogenous acetylcholine in anesthetized dogs. J Cardiovasc Pharmacol 1992;20:870-4
20. Koshika T, Nagayama T, Kimura T, Satoh S. Glucagon facilitates adrenal catecholamine release mediated by nicotinic receptors but not by muscarinic receptors in anesthetized dogs. J Cardiovasc Pharmacol 1996;28:585-90
21. Malhotra RK, Wakade TD, Wakade AR. Cross-communication between acetylcholine and VIP in controlling catecholamine secretion by affecting cAMP, inositol triphosphate, protein kinase C, and calcium in rat adrenal medulla. J Neurosci 1989;9:4150-7
22. Marriott D, Adams M, Boarder MR. Effect of forskolin and prostaglandin El on stimulus secretion coupling in cultured bovine adrenal chromaffin cells. J Neurochem 1988;50: 616-23
23. 2+ uptake. Neurosci Lett 1988;87: 266-70
24. Morita K, Dohi T, Kitayama S, Tsujimoto A. Enhancement of acetylcholine-evoked catecholamine release from perfused dog adrenals by elevating cyclic AMP levels. Arch Int Pharmacodyn Ther 1985;275:208-16
25. Morita K, Dohi T, Kitayama S, Koyama Y, Tsujimoto A. Enhancement of stimulation-evoked catecholamine release from cultured bovine adrenal chromaffin cells by forskolin. J Neurochem 1987a;48:243-7
26. 2+ fluxes in cultured bovine adrenal chromaffin cells are enhanced by forskolin. J Neurochem 1987b;48:248-52
27. Nakazato Y, Ohga A, Oleshanskly M, Tomita U, Yamada Y. Voltage-independent catecholamine release mediated by the activation of muscarinic receptors in guinea-pig adrenal glands. Br J Pharmacol 1988;93:101-9
28. Negishi M, Ito S, Hayaishi O. Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxininsensitive manner. J Biol Chem 1989;264:3916-23
29. Shimamura T, Kimura T, Satoh S. Effects of pirenzepine, AFDX 116 and gallamine on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation: Interaction of M1 and M2 receptors with nicotinic receptors. J Pharmacol Exp Ther 1991;257:369-73
30. Tsujimoto A, Morita K, Kitayama S, Dohi T. Facilitation of acetylcholine-evoked catecholamine release by cyclic AMP on isolated perfused dog adrenal glands. Arch Int Pharmacodyn Ther 1986;279:304-13
31. Wilson SP. Vasoactive intestinal peptide elevates cyclic AMP levels and potentiates secretion in bovine adrenal chromaffin cells. Neuropeptides 1988;11:17-21
32. 2+. Neurosci Lett 1988;90:338-42