Combined oral treatment with racemic and meso-2,3-dimercaptosuccinic acid for removal of mercury in rats

Pharmacology and Toxicology

Volumn 81, Issue 5, 1997, Pages 242-244

  Kostial, Krista ^a   Restek Samaržija, Nada ^a   Blanuša, Maja ^a   Piasek, Martina ^a   Jones, Mark M ^b   Singh, Pramod K ^b,c  

^a INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

^b VANDERBILT UNIVERSITY   (United States)

^c Ellington Agriculture Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATING AGENT; MERCURIC CHLORIDE; MERCURY; MERCURY 203; SUCCIMER;

ANIMAL MODEL; ARTICLE; CHELATION; DRUG EFFICACY; HEAVY METAL POISONING; INTOXICATION; MERCURIALISM; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RACEMIC MIXTURE; RAT; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

ANIMALIA;

EID: 0030695946     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1997.tb00054.x     Document Type: Article

References (9)

1. Egorova, L. G., I. E. Okonishnikova, V. L. Nirenburg & I. Ya Postovskii: Complex formation of certain metals with dimercaptosuccinic acid stereoisomer. Him. Farm Ž. 1972, 6, 14-16 (in Russian).
2. Goyer, R. A.: Chelation of toxic metals: Current interest. Environ. Health Perspect. 1995, 103, 988-989.
3. Goyer, R. A., M. E. Cherian, M. M. Jones & J. R. Reingart: Role of chelating agents for prevention, intervention and treatment of exposures of toxic metals. Environ. Health Perspect. 1995,103, 1048-1052.
4. Jones, M. M., P. K. Singh, K. Kostial, M. Blanuša, M. Piasek & N. Restek-Samaržija: Comparative in vivo lead mobilization by meso- and rac-2,3-dimercaptosuccinic acid in albino Wistar rats. Pharmacology & Toxicology 1997, 80, 182-186.
5. Kostial, K., N. Restek-Samaržija, M. Blanuša, M. Piasek, LJ. Prester, M. M. Jones & P. K. Singh: Racemic-2,3-dimercaptosuccinic acid for inorganic mercury mobilization in rats. J. Appl. Toxicol. 1997, 17, 71-74.
6. Okonishnikova, I.E.: Comparative effectiveness of antidotal activity of spacial isomers of dimercaptosuccinic acid in mercury poisoning. Gig. Tr. Prof. Zabol. 1970, 14, 18-22 (in Russian).
7. Okonishnikova, I.E. L. G. Egorova, V. L. Nirenburg & I. Ya. Postovskii: The complexity of properties of dimercaptosuccinic acid-s spacial isomers. Him. Farm. Ž. 1970, 1, 21-24 (in Russian).
8. Prester, Lj., N. Restek-Samaržija, M. Blanuša, M. Piasek, K. Kostial, M. M. Jones & P. K. Singh. Comparative efficacy of racemic and meso-2,3-dimercaptosuccinic acid to mobilize mercury in rats. Proceedings of the Third Symposium of the Croatian Radiation Protection Association, Zagreb, Croatia. Eds.: D. Kubelka and J. Kovač. Printing House "Vajčner", d.o.o., Zagreb, 1996, p. 155-160.
9. Restek-Samaržija, N., M. Piasek, K. Kostial, M. Blanuša, M. M. Jones & P. K. Singh: Lead mobilization after treatment with meso- and racemic-2,3-dimercaptosuccinic acid in rats. 35th European Congress of Toxicology-EUROTOX'96, Alicante, Spain 1996. Toxicol. Lett. 1996, 88 (Suppl 1), 58 (abstract).