N-dibenzylphospho-N'-3-(2,6-dichlorophenyl) propyl-guanidine is a bisubstrate-analog for creatine kinase

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1342, Issue 1, 1997, Pages 83-89

  Min, Kyung Lyum ^a   Steghens, Jean Paul ^a   Henry, Robert ^b   Doutheau, Alain ^b   Collombel, Christian ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b UNIVERSITÉ DE LYON   (France)

Author keywords

Bisubstrate analog; Creatine kinase; Inhibitor; Kinetic mechanism

Indexed keywords

ADENOSINE DIPHOSPHATE; CREATINE KINASE; CREATINE KINASE BB; CREATINE KINASE MM; GUANIDINE DERIVATIVE; ISOENZYME; N DIBENZYLPHOSPHO N' [3 (2,6 DICHLOROPHENYL)PROYL]GUANIDINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; ENZYME ACTIVITY; ENZYME BINDING; HUMAN; PRIORITY JOURNAL;

ADENOSINE DIPHOSPHATE; BRAIN; CREATINE KINASE; ENZYME INHIBITORS; GUANIDINES; HUMANS; HYDROGEN-ION CONCENTRATION; ISOENZYMES; KINETICS; MODELS, CHEMICAL; MUSCLE, SKELETAL; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0030695481     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(97)00088-5     Document Type: Article

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