Immunoelectron microscopic localization of plasminogen activator inhibitor type I (PAI-1) in smooth muscle cells from morphologically normal and atherosclerotic human arteries

Ultrastructural Pathology

Volumn 21, Issue 6, 1997, Pages 527-536

  Taatjes, Douglas J ^a   Wadsworth, Marilyn ^b   Absher, P Marlene ^b   Sobel, Burton E ^b   Schneider, David J ^b  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Human vessels; Immunoelectron microscopy; PAI 1; Smooth muscle cells

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; FIBRINOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

EID: 0030695297     PISSN: 01913123     EISSN: None     Source Type: Journal    
DOI: 10.3109/01913129709016369     Document Type: Article

References (30)

1. Ross R. Cell biology of atherosclerosis. Annu Rev Physiol. 1995;57:791-804.
2. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
3. Stary HC, Blankenhorn DH, Chandler AB, et al. A definition of the intima of human arteries and of its atherosclerosisprone regions: a report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association, Special report. Circulation. 1992;85:391-405.
4. Stary HC, Chandler AB, Glagov S, et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis: a report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association, Special report. Arterioscler Thromb. 1994;14:840-856.
5. Stary HC, Chandler AB, Dinsmore RE, et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis: a report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association, Special report. Arterioscler Thromb Vase Biol. 1995;15:1512-1531.
6. Libby P. Molecular basis of the acute coronary syndromes. Circulation. 1995;91:2844-2850.
7. Takaichi S, Yutani C, Fujita H, Yamamoto A. Ultrastructural studies on the phenotypic modulation of human intimal smooth muscle cells. Atherosclerosis. 1993;100:197-211.
8. Campbell GR, Campbell JH. Smooth muscle phenotypic changes in arterial wall homeostasis: Implications for the pathogenesis of atherosclerosis. Exp Mol Pathol. 1985;42:139-162.
9. Campbell GR, Campbell JH, Manderson JA, Horrigan S, Rennick RE. Arterial smooth muscle: a multifunctional mesenchymal cell. Arch Pathol Lab Med. 1988;112:977-986.
10. He CS, Wilhelm SM, Pentland AP, et al. Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci USA. 1989;86:2632-2637.
11. Raghunath PN, Tomaszewski JE, Brady ST, Caron RJ, Okada SS, Barnathan ES. Plasminogen activator system in human coronary atherosclerosis. Arterioscler Thromb Vase Biol. 1995;15:1432-1443.
12. Schneider DJ, Ricci MA, Taatjes DJ, et al. Changes in arterial expression of fibrinolytic system proteins in atherogenesis. Arterioscler Thromb Vase Biol. 1997; in press.
13. Padro T, Emeis JJ, Steins M, Schmid KW, Kienast J. Quantification of plasminogen activators and their inhibitors in the aortic vessel wall in relation to the presences and severity of atherosclerotic disease. Arterioscler Thromb Vase Biol. 1995;15:893-902.
14. Schneidermann J, Sawdey SM, Keeton MR, et al. Increased type 1 plasminogen activator inhibitor-1 gene expression in atherosclerotic human arteries. Proc Natl Acad Sci USA. 1992;89:6998-7002.
15. Lupu F, Bergonzelli GE, Heim DA, et al. Localization and production of plasminogen activator inhibitor-1 in human healthy and atherosclerotic arteries. Arterioscler Thromb. 1993;13:1090-1100.
16. Chomiki N, Henry M, Alessi MC, Anfosso F, Juhan-Vague I. Plasminogen activator inhibitor-1 expression in human liver and healthy or atherosclerotic vessel walls. Thromb Haemostas. 1994;72:44-53.
17. Liou W, Geuze HJ, Slot JW. Improving structural integrity of cryosections for immunogold labeling. Histochem Cell Biol. 1996;106:41-58.
18. Tokuyasu KT. Use of poly(vinylpyrrolidone) and poly(vinyl alcohol) for cryoultramicrotomy. Histochem J. 1989;21:163-171.
19. Schneider DJ, Absher PM, Ricci MA. The dependence of augmentation of arterial endothelial cell expression of plasminogen activator inhibitor type 1 by insulin on soluble factors released from vascular smooth muscle cells. Circulation. 1997; in press.
20. 2-terminal fragment that includes the cytoplasmic and transmembrane domain is sufficient for Golgi retention. J Biol Chem. 1992;267:9241-9247.
21. Slot JW, Geuze HJ. A new method of preparing gold probes for multiple-labeling cytochemistry. Eur J Cell Biol. 1985;38:87-93.
22. Roth J. The protein A-gold (pAg) technique: a qualitative and quantitative approach for antigen localization on thin sections. In: Bullock GR, Petrusz P, eds. Techniques in Immunocytochemistry. Vol 1. London: Academic; 1982:108-133.
23. Nielsen LS, Andreasen PA, Grondahl-Hansen J, Huang J-Y, Kristensen P, Dano K. Monoclonal antibodies to human 54,000 molecular weight plasminogen activator inhibitor from fibrosarcoma cells: inhibitor neutralization and one-step affinity purification. Thromb Haemostas. 1986;55:206-212.
24. Ellis V, Dano K. The urokinase receptor and the regulation of cell surface plasminogen activation. Fibrinolysis. 1992;6(S4):27-32.
25. He CS, Wilhelm SM, Pentland AP, et al. Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci USA. 1989;86:2632-2637.
26. Chapman HA Jr, Stone OL. Co-operation between plasmin and elastase degradation by intact murine macrophages. Biochem J. 1989;222:721-725.
27. Chapman HA Jr, Reilly JJ Jr, Kobzik L. Role of plasminogen activator in degradation of extracellular matrix protein by live human alveolar macrophages. Am Rev Respir Dis. 1988;137:412-419.
28. Clowes AW, Clowes MM, Au YP, Reidy MA, Belin D. Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery. Circ Res. 1990;67:61-67.
29. Sawa H, Sobel BE, Fujii S. Potentiation by hypercholesterolemia of the induction of aortic intramural synthesis of plasminogen activator inhibitor type 1 by endothelial injury. Circ Res. 1993;73:671-680.
30. Sawa H, Lundgren C, Sobel BE, Fujii S. Increased intramural expression of plasminogen activator inhibitor type 1 after balloon injury: a potential progenitor of restenosis. J Am Coll Cardiol. 1994;24:1742-1748.