Effects of pentobarbital on pharmacokinetics and pharmacodynamics of a potent fibrinogen receptor antagonist, L-734 217, in dogs

Biopharmaceutics and Drug Disposition

Volumn 18, Issue 8, 1997, Pages 649-663

  Prueksaritanont, T ^a   Stranieri, M T ^a   Hand, E I ^a   Ellis, J D ^a   Holahan, M A ^a   Sitko, G R ^a   Cook, J J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Anesthesia; Drug interactions; Fibrinogen receptor antagonist; Pentobarbital; Pharmacodynamics; Pharmacokinetics

Indexed keywords

FIBRINOGEN RECEPTOR ANTAGONIST; L 734217; PENTOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG PROTEIN BINDING; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PHARMACODYNAMICS; PHARMACOKINETICS; THROMBOCYTE AGGREGATION INHIBITION;

ADENOSINE DIPHOSPHATE; ADJUVANTS, ANESTHESIA; ANIMALS; AREA UNDER CURVE; BETA-ALANINE; COLLAGEN; CROSS-OVER STUDIES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; PENTOBARBITAL; PIPERIDINES; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RADIOIMMUNOASSAY;

EID: 0030695256     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199711)18:8<649::AID-BDD51>3.0.CO;2-T     Document Type: Article

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