Reconstitution of a functional bovine papillomavirus type 1 origin of replication reveals a modular tripartite replicon with an essential AT-rich element

Virology

Volumn 237, Issue 2, 1997, Pages 198-208

  McShan, Gina D ^a   Wilson, Van G ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BINDING SITE; CATTLE; CONTROLLED STUDY; DNA REPLICATION; DNA REPLICATION ORIGIN; NONHUMAN; PAPILLOMA VIRUS; PRIORITY JOURNAL; REPLICON; VIRUS REPLICATION;

BOS TAURUS; BOVINAE; BOVINE PAPILLOMAVIRUS; BOVINE PAPILLOMAVIRUS TYPE 1; BOVINE PARVOVIRUS; EUKARYOTA; PAPILLOMAVIRUS;

EID: 0030695184     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8793     Document Type: Article

References (44)

1. Bell S. P., Stillman B. ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature. 357:1992;128-134.
2. Benbow R. M., Zhao J., Larson D. D. On the nature of origins of DNA replication in eukaryotes. Bioessays. 10:1992;661-670.
3. Berg M., Stenlund A. Functional interactions between papillomavirus E1 and E2 proteins. J. Virol. 71:1997;3853-3863.
4. Blitz I. L., Laimins L. A. The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro. J. Virol. 65:1991;649-656.
5. Bonne-Andrea C., Santucci S., Clertant P., Tillier F. Bovine papillomavirus E1 protein binds specifically DNA polymerase α but not replication protein A. J. Virol. 69:1995;2341-2350.
6. Bonne-Andrea C., Tillier F., McShan G. D., Wilson V. G., Clertant P. Bovine papillomavirus type 1 (BPV1) DNA replication: The transcriptional activator E1 acts in vitro as a specificity factor. J. Virol. 71:1997;6805-6815.
7. Borowiec J. A., Dean F. B., Bullock P. A., Hurwitz J. Binding and unwinding - How T antigen engages the SV40 origin of DNA replication. Cell. 60:1990;181-184.
8. Coverley D., Laskey R. A. Regulation of eukaryotic DNA replication. Annu. Rev. Biochem. 63:1994;745-776.
9. Depamphilis M. L. Transcriptional elements as components of eukaryotic origins of DNA replication. Cell. 52:1988;635-638.
10. DePamphilis M. L. Eukaryotic DNA replication: Anatomy of an Origin. Annu. Rev. Biochem. 62:1993;29-63.
11. Fangman W. L., Brewer B. J. Activation of replication origins within yeast chromosomes. Annu. Rev. Cell. Biol. 7:1991;375-402.
12. Fanning E. Control of SV40 DNA replication by protein phosphorylation: A model for cellular DNA replication? Trends Cell Biol. 4:1994;250-255.
13. Gavin K. A., Hidaka M., Stillman B. Conserved initiator proteins in eukaryotes. Science. 270:1995;1667-1671.
14. Gilbert D. M., Cohen S. M. Bovine papilloma virus plasmids replicate randomly in mouse fibroblasts throughout S phase of the cell cycle. Cell. 50:1987;59-68.
15. Gopalakrishnan V., Khan S. A. E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication. Proc. Natl. Acad. Sci. USA. 91:1994;9597-9601.
16. Grossel M. J., Sverdrup F., Breiding D. E., Androphy E. J. Transcriptional activation function is not required for stimulation of DNA replication by bovine papillomavirus type 1 E2. J. Virol. 70:1996;7264-7269.
17. Holt S. E., Wilson V. G. Mutational analysis of the 18-base-pair inverted repeat element at the bovine papillomavirus origin of replication - Identification of critical sequences for E1 binding and in vivo replication. J. Virol. 69:1995;6525-6532.
18. Holt S. E., Schuller G., Wilson V. G. DNA binding specificity of the bovine papillomavirus E1 protein is determined by sequences contained within an 18-base-pair inverted repeat element at the origin of replication. J. Virol. 68:1994;1094-1102.
19. Koetsier P. A., Schorr J., Doerfler W. A rapid optimized protocol for downward alkaline Southern blotting of DNA. Bio Techniques. 15:1993;260-262.
20. Kowalski D., Eddy M. J. The DNA unwinding element: A novel, cis-acting component that facilitates opening of the Escherichia coli replication origin. EMBO. J. 8:1989;4335-4344.
21. Li R., Botchan M. R. Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc. Natl. Acad. Sci. USA. 91:1994;7051-7055.
22. Lin S., Kowalski D. DNA helical stability facilitates initiation at the SV40 replication origin. J. Mol. Biol. 235:1994;496-507.
23. Lu J. Z., Sun Y. N., Rose R. C., Bonnez W., McCance D. J. Two E2 binding sites (E2BS) alone or one E2BS plus an A/T-rich region are minimal requirements for the replication of the human papillomavirus type 11 origin. J. Virol. 67:1993;7131-7139.
24. Matsumoto T., Eki T., Hurwitz J. Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system. Proc. Natl. Acad. Sci. USA. 87:1990;9712-9716.
25. Melendy T., Sedman J., Stenlund A. Cellular Factors Required for Papillomavirus DNA Replication. J. Virol. 69:1995;7857-7867.
26. Mohr I. J., Clark R., Sun S., Androphy E. J., MacPherson P., Botchan M. R. Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science. 250:1990;1694-1699.
27. Müller F., Seo Y.-S., Hurwitz J. Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins. J. Biol. Chem. 269:1994;17086-17094.
28. Nallaseth F. S., DePamphilis M. L. Papillomavirus contains cis-acting sequences that can suppress but not regulate origins of DNA replication. J. Virol. 68:1994;3051-3064.
29. Natale D. A., Schubert A. E., Kowalski D. DNA helical stability accounts for mutational defects in a yeast replication origin. Proc. Natl. Acad. Sci. USA. 89:1992;2654-2658.
30. Park P., Copeland W., Yang L., Wang T., Botchan M. R., Mohr I. J. The cellular DNA polymerase Alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc. Natl. Acad. Sci. USA. 91:1994;8700-8704.
31. Russell J., Botchan M. R. cis-acting components of human papillomavirus (HPV) DNA replication: Linker substitution analysis of the HPV type 11 origin. J. Virol. 69:1995;651-660.
32. Sedman J., Stenlund A. Co-operative interaction between the initiator E1 and the transcriptional activator E2 is required for replicator specific DNA replication of bovine papillomavirus in vivo and in vitro. EMBO. J. 14:1995;6218-6228.
33. Sedman J., Stenlund A. The initiator protein E1 binds to the bovine papillomavirus origin of replication as a trimeric ring-like structure. EMBO. J. 15:1996;5085-5092.
34. Sedman T., Sedman J., Stenlund A. Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus. J. Virol. 71:1997;2887-2896.
35. Seo Y.-S., Müller F., Lusky M., Gibbs E., Kim H.-Y., Phillips B., Hurwitz J. Bovine papilloma virus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proc. Natl. Acad. Sci. USA. 90:1993a;2865-2869.
36. Seo Y. S., Müller F., Lusky M., Hurwitz J. Bovine papilloma virus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication. Proc. Natl. Acad. Sci. USA. 90:1993b;702-706.
37. Seo Y. S., Müller F., Lusky M., Gibbs E., Kim H. Y., Philips B., Hurwitz J. Bovine papillomavirus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proc. Natl. Acad. Sci. USA. 90:1993c;2865-2869.
38. Spalholz B. A., McBride A. A., Sarafi T., Quintero J. Binding of bovine papillomavirus E1 to the origin is not sufficient for DNA replication. Virology. 193:1993;201-212.
39. Sverdrup F., Khan S. A. Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins. J. Virol. 68:1994;505-509.
40. Sverdrup F., Khan S. A. Two E2 binding sites alone are sufficient to function as the minimal origin of replication of human papillomavirus type 18 DNA. J. Virol. 69:1995;1319-1323.
41. Ustav E., Ustav M., Szymanski P., Stenlund A. The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator. Proc. Natl. Acad. Sci. USA. 90:1993;898-902.
42. Ustav M., Stenlund A. Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J. 10:1991;449-457.
43. Ustav M., Ustav E., Szymanski P., Stenlund A. Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. EMBO J. 10:1991;4321-4329.
44. Yang L., Mohr I., Fouts E., Lim D. A., Nohaile M., Botchan M. The E1 protein of bovine papilloma virus 1 is an ATP-dependent DNA helicase. Proc. Natl. Acad. Sci. USA. 90:1993;5086-5090.