Regional difference in lipolysis caused by a β-adrenergic agonist as determined by the microdialysis technique

Acta Physiologica Scandinavica

Volumn 161, Issue 4, 1997, Pages 481-487

  Iwao, N ^a   Oshida, Y ^b   Sato, Y ^b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Ethanol technique; Glycerol; Lipolysis; Local blood flow; Microdialysis; Subcutaneous adipose tissue; Visceral adipose tissue; Adrenergic effect

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE;

ADIPOSE TISSUE; ADIPOSE TISSUE BLOOD FLOW; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; LIPOLYSIS; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION;

EID: 0030694773     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1997.00234.x     Document Type: Article

References (30)

1. Arner, P. & Bolinder, J. 1991. Microdialysis of adipose tissue. J Internal Med 230, 381-386.
2. Arner, P., Bolinder, J., Eliasson, A., Lundin, A. & Ungerstedt, U. 1988. Microdialysis of adipose tissue and blood for in vivo lipolysis studies. Am J Physiol 255, E737-E742.
3. Arner, P., Hellström, L., Wahrenberg, H. & Brönnegard, M. 1990. Beta-adrenoceptor expression in human fat cells from different regions. J Clin Invest 86, 1595-1600.
4. Björntorp, P. 1990. Obesity and adipose tissue distribution as risk factors for the development of disease. Infusionstherapie 17, 24-27.
5. Bray, G.A., Inoue, S. & Nishizawa, Y. 1981. Hypothalamic obesity: The autonomic hypothesis and the lateral hypothalamus. Diabetologia 20, 366-377.
6. Cimmino, M., Agosto, A., Minaire, Y. & Géloën, A. 1995. In situ regulation of lipolysis by insulin and norepinephrine: A microdialysis study during euglycemic-hyperinsulinemic clamp. Metabolism 44, 1513-1518.
7. Darimont, C., Saint-Marc, P., Ailhard, G. & Négrel, R. 1996. Modulation of vascular tone and glycerol levels measured by in situ microdialysis in rat adipose tissue. Am J Physiol 271, E631-E635.
8. 3-adrenoceptor in man. J Clin Invest 95, 2239-2245.
9. Fain, J.N. & García-Sáinz, J.A. 1983. Adrenergic regulation of adipocyte metabolism. J Lipid Res 24, 945-966.
10. Fujioka, S., Matsuzawa, Y., Tokunaga, K., Keno, Y., Kobatake, T. & Tarui, S. 1991. Treatment of visceral fat obesity. Int J Obes 15, 59-65.
11. 2 adrenoceptors in regulating lipid mobilization from human adipose tissue. J Clin Invest 91, 1997-2003.
12. Hickner, R.C., Bone, D., Ungerstedt, U., Jorfeldt, L. & Henriksson, J. 1994. Muscle blood flow during intermittent exercise: comparison of the microdialysis ethanol technique and 133Xe clearance. Clin Sci 86, 15-25.
13. Hickner, R.C., Ekelund, U., Mellander, S., Ungerstedt, U. & Henriksson, J. 1995. Muscle blood flow in cats: comparison of microdialysis ethanol technique with direct measurement. J Appl Physiol 79, 638-647.
14. Hickner, R.C., Rosdahl, H., Borg, I., Ungerstedt, U., Jorfeldt, L. & Henriksson, J. 1991. Ethanol may be used with the microdialysis technique to monitor blood flow changes in skeletal muscle: dialysate glucose concentration is blood-flow-dependent. Acta Physiol Scand 143, 355-356.
15. Hickner, R.C., Rosdahl, H., Borg, I., Ungerstedt, U., Jorfeldt, E. & Henriksson, J. 1992. The ethanol technique of monitoring local blood flow changes in rat skeletal muscle: implications for microdialysis. Acta Physiol Scand 146, 87-97.
16. Jansson, P.A., Smith, U. & Lonnroth, P. 1990. Interstitial glycerol concentration measured by microdialysis in two subcutaneous regions in humans. Am J Physiol 258, E918-E922.
17. Kissebah, A.H., Vydelingum, N., Murray, R., Evans, D.J., Hartz, A.J., Kalkhoff, R.K. & Adams, P.W. 1982. Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 54, 254-260.
18. Klein, S., Coyle, E.F. & Wolfe, R.R. 1995. Effect of exercise on lipolytic sensitivity in endurance-trained athletes. J Appl Physiol 78, 2201-2206.
19. 2;-adrenergic receptor mRNA in man. J Clin Invest 91, 344-349.
20. Lönnroth, P., Jansson, P.A. & Smith, U. 1987. A microdialysis method allowing characterization of intercellular water space in humans. Am J Physiol 253, E228-E231.
21. Matsuzawa, Y., Shimomura, I., Nakamura, T., Keno, Y. & Tokunaga, K. 1994. Pathophysiology and pathogenesis of visceral fat obesity. Diabetes Res Clin Pract 24, S111-S116.
22. Oshida, Y., Ohsawa, I., Sato, J. & Sato, Y. 1993. Effects of adrenodemedullation on in vivo insulin-stimulated glucose utilization in relation to glycolysis in rat peripheral tissue. Endocr J 40, 99-106.
23. Oshida, Y., Yang, W.P., Wu, W., Ohsawa, I., Sato, J. & Sato, Y. 1992. Effect of muscle constriction on 3-hydroxybutyrate uptake using the microdialysis technique. Horm Metab Res 24, 546-547.
24. Rebuffé-Scrive, M., Andersson, B., Olbe, L. & Björntorp, P. 1989. Metabolism of adipose tissue in intraabdominal depots of nonobese men and women. Metabolism 38, 453-458.
25. Shimomura, I., Tokunaga, K., Kotani, K., Keno, Y., Yanase-Fujiwara, M., Kanosue, K., Jiao, S., Funahashi, T., Kobatake, T., Yamamoto, T. & Matsuzawa, Y. 1993. Marked reduction of acyl-CoA synthetase activity and mRNA in intra-abdominal visceral fat by physical exercise. Am J Physiol 265, E44-E50.
26. Sztalryd, C. & Kraemer, F.B. 1994. Differences in hormone-sensitive lipase expression in white adipose tissue from various anatomic locations of the rat. Metabolism 43, 241-247.
27. Tossman, U. & Ungerstedt, U. 1986. Microdialysis in the study of extracellular levels of amino acids in the rat brain. Acta Physiol Scand 128, 9-14.
28. Ungerstedt, U. 1991. Microdialysis - principles and applications for studies in animals and man. J Internal Med 230, 365-373.
29. Wahrenberg, H., Lönnqvist, F. & Arner, P. 1989. Mechanisms underlying regional differences in lipolysis in human adipose tissue. J Clin Invest 84, 458-467.
30. Yang, W.P., Oshida, Y., Wu, W., Sato, J., Ohsawa, I. & Sato, Y. 1995. Effects of daily voluntary running on in vivo insulin action in rat skeletal muscle and adipose tissue as determined by the microdialysis technique. Int J Sports Med 16, 99-105.