Gd-EOB-DTPA and Yb-EOB-DTPA: Two prototypic contrast media for CT detection of liver lesions in dogs

Radiology

Volumn 205, Issue 2, 1997, Pages 361-366

  Schmitz, Stephan A ^a   Wagner, Susanne ^a   Schuhmann Giampieri, Gabriele ^b   Krause, Werner ^b   Bollow, Matthias ^c   Wolf, Karl Jürgen ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BAYER PHARMA AG   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Computed tomography (CT), contrast media; Contrast media, comparative studies; Contrast media, experimental studies; Gadolinium; Liver neoplasms, diagnosis; Ytterbium

Indexed keywords

GADOLINIUM ETHOXYBENZYLPENTETATE; IODINATED POPPYSEED OIL; PENTETIC ACID DERIVATIVE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; YTTERBIUM ETHOXYBENZYLPENTETATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DOG; DRUG DISTRIBUTION; IMAGE QUALITY; INTRAVENOUS DRUG ADMINISTRATION; LIVER TUMOR; NONHUMAN; PRIORITY JOURNAL;

EID: 0030694684     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiology.205.2.9356615     Document Type: Article

References (21)

1. Hamm B, Vogl TJ, Branding G, et al. Focal liver lesions: MR imaging with Mn-DPDP - initial clinical results in 40 patients. Radiology 1992; 182:167-174.
2. Schuhmann-Giampieri G, Schmitt-Willich H, Press WR, Negishi C, Weinmann HJ, Speck U. Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology 1992; 183:59-64.
3. Reimer P, Rummeny EJ, Daldrup HE, et al. Clinical results with Resovist: a phase 2 clinical trial. Radiology 1995; 195:489-496.
4. Weissleder R. Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology 1994; 193:593-595.
5. Mühler A, Clément O, Vexler V, Berthezéne Y, Rosenau W, Brasch RC. Gadoliniumethoxybenzyl-DTPA hepatobiliary enhancement: comparison of spin echo and STIR imaging for detection of experimental liver metastases. Radiology 1992; 184:207-213.
6. 153Gd-EOB-DTPA scintigraphy in rats. Invest Radiol 1996; 31:154-160.
7. Schmitz SA, Wagner S, Schuhmann-Giampieri G, Krause W, Wolf KJ. A prototype liver-specific contrast medium for CT: preclinical evaluation of gadoxetic acid disodium, or Gd-EOB-DTPA. Radiology 1997; 202:407-412.
8. Schmitz SA, Häberle HJ, Balzer T, Shamsi K, Boese-Landgraf J, Wolf KJ. Detection of focal liver lesions: CT of the hepatobiliary system with gadoxetic acid disodium, or Gd-EOB-DTPA. Radiology 1997; 202:399-405.
9. Schmitz SA, Wagner S, Schuhmann-Giampieri G, Wolf KJ. Evaluation of gadobutrol in a rabbit model as a new lanthanide contrast agent for computed tomography. Invest Radiol 1995; 30:644-649.
10. Krause W, Schuhmann-Giampieri G, Bauer M, Press WR, Muschick P. Ytterbium- and dysprosium-EOB-DTPA: a new prototype of liver-specific contrast agents for computed tomography. Invest Radiol 1996, 31:502-511.
11. Miller DL, Vermess M, Doppman JL, et al. CT of the liver and spleen with EOE-13: review of 225 examinations. AJR 1984; 143:235-243.
12. Perkerson RB, Erwin BC, Baumgartner BR, et al. CT densities in delayed iodine hepatic scanning. Radiology 1985; 155:445-446.
13. Miller DL, Simmons JT, Chang R, et al. Hepatic metastases detection: comparison of three CT contrast enhancement methods. Radiology 1987; 165:785-790.
14. Unger E, Gutierrez F. Ytterbium-DTPA: a potential intravascular contrast agent. Invest Radiol 1986; 21:802-807.
15. Zwicker C, Langer M, Langer R, Keske U. Comparison of iodinated and noniodinated contrast media in computed tomography. Invest Radiol 1991; 26:162-164.
16. Havron A, Davis M, Seltzer S, Paskin-Hurlburt A, Hessel S. Heavy metal particulate contrast materials for computed tomography of the liver. J Comput Assist Tomogr 1980; 4:642-648.
17. Seltzer S, Douglass F, Davis M, et al. Hepatic contrast agents for computed tomography: high atomic number particulate materials. J Comput Assist Tomogr 1981; 5:370-374.
18. Engelbrech V, Koch JA, Rassek M, Mödder U. Gadolinium-DTPA and gadodiamide as an alternative contrast medium for CT. ROFO 1996; 165:24-28.
19. Weast RC, Selby SM, eds. Handbook of chemistry and physics: a ready-reference book of chemical and physical data. Cleveland, Ohio: Chemical Rubber, 1981.
20. Bruneton JN, Falewée MN, François E, et al. Liver, spleen, and vessels: preliminary clinical results of CT with perfluorooctylbromide. Radiology 1989; 170:179-183.
21. Hamm B, Staks T, Mühler A, et al. Phase I clinical evaluation of Gd-EOB-DTPA as a hepatobiliary MR contrast agent: safety, pharmacokinetics, and MR imaging. Radiology 1995; 195:785-792.