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Volumn 7, Issue 23, 1997, Pages 2945-2950

Synthesis and in vitro cytotoxic activity of novel hexahydro-2H-pyrido[1,2-b]isoquinolines against human brain tumor cell lines

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYTOTOXIC AGENT; ISOQUINOLINE DERIVATIVE; PYRIDINE DERIVATIVE;

EID: 0030694471     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10114-7     Document Type: Article
Times cited : (10)

References (17)
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    • Nicolaou, K. C.; Dai, W.-M.; Guy, R. K. Angew. Chem. 1994, 106, 38; Angew. Chem. Int. Ed. Engl. 1994, 33, 15.
    • (1994) Angew. Chem. Int. Ed. Engl. , vol.33 , pp. 15
  • 4
    • 0029397222 scopus 로고
    • and references cited therein
    • Plate, K. H.; Risal, W. Glia 1995, 15, 339 and references cited therein.
    • (1995) Glia , vol.15 , pp. 339
    • Plate, K.H.1    Risal, W.2
  • 7
    • 0027310608 scopus 로고
    • Lienard, P.; Quirion, J.-C.; Husson, H.-P. Tetrahedron Lett. 1991, 32, 2489; Tetrahedron 1993, 49, 3995.
    • (1993) Tetrahedron , vol.49 , pp. 3995
  • 8
    • 24444440872 scopus 로고
    • (Colgate-Palmolive), US 3661915, 1972
    • Suh, J. T.; Schnettler, R. A. (Colgate-Palmolive), US 3661915, 1972 [Chem. Abstr. 1972, 77, 126455k].
    • (1972) Chem. Abstr. , vol.77
    • Suh, J.T.1    Schnettler, R.A.2
  • 9
    • 33748820668 scopus 로고
    • (Colgate-Palmolive), US 3578668, 1971
    • Schnettler, R. A.; Suh, J. T. (Colgate-Palmolive), US 3578668, 1971 [Chem. Abstr 1971, 75, 35795p].
    • (1971) Chem. Abstr , vol.75
    • Schnettler, R.A.1    Suh, J.T.2
  • 10
    • 24444432237 scopus 로고
    • (Sandoz Inc.), US 3408352, 1969
    • Hardtmann, G. E. (Sandoz Inc.), US 3408352, 1969 [Chem. Abstr. 1969, 70, 47318v].
    • (1969) Chem. Abstr. , vol.70
    • Hardtmann, G.E.1
  • 13
    • 85036678176 scopus 로고    scopus 로고
    • note
    • All new compounds gave satisfactory analytical and spectroscopic data.
  • 15
    • 85036677088 scopus 로고    scopus 로고
    • note
    • -3, Flack parameter 0(3), hydrogens calculated and riding. All data were collected on a Enraf-Nonius CAD4 diffractometer, programs used: MolEN, SHELXS-86, SHELXL-93, SCHAKAL-92. The authors have deposited atomic coordinates for the structure with the Cambridge Crystallographic Data Centre. The coordinates can be obtained on request from the Director, Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, CB2 1EZ.
  • 16
    • 85036680502 scopus 로고    scopus 로고
    • note
    • -7 M (for all experiments, n=24 for controls, n=8 for each concentration). 72 hours later the MTT-test was performed as described to measure the cell survival [see ref. 15].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.