Diabetes and hypertension in rodent models

Annals of the New York Academy of Sciences

Volumn 827, Issue , 1997, Pages 64-84

  Klöting, Ingrid ^a   Berg, Sabine ^a   Kovács, Peter ^a   Voigt, Birger ^a   Vogt, Lutz ^a   Schmidt, Siegfried ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CHROMOSOMAL LOCALIZATION; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; GENE MAPPING; GENETIC LINKAGE; HEART RATE; HEREDITY; HYPERTENSION; MOTOR ACTIVITY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; ONSET AGE; PHENOTYPE; QUANTITATIVE TRAIT; RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALIA; RODENTIA;

EID: 0030691808     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb51822.x     Document Type: Conference Paper

References (37)

1. TODD, J. A., T. J. AlTMAN, R. J. CORNALL, S. GHOSH, J. R. S. HALL, C. M. HEARNE, A. W. KNIGHT, J. M. LOVE, M. A. MCALEER, J. B. PRINS, N. RODRIGUES, M. LATHROP, A. PRESSEY, N. H. DELAROTE, L. B. PETERSON & L. S. WICKER. 1991. Genetic analysis of autoimmune type 1 diabetes mellitus in mice. Nature 351: 542-547.
2. GHOSH, P., S. M. PALMER, N. R. RODRIGUES, H. J. CORDELL, C. M. HEARNE, R. J. CORNALL, J. B. PRINS, P. McSHANE, G. M. LATHROP & L. B. PETERSON. 1993. Polygenic control of autoimmune diabetes in nonobese diabetic mice. Nat. Genet. 4: 404-409.
3. WICKER, L. S., J. A. TODD & L. B. PETERSON. 1995. Genetic control of autoimmune diabetes in the NOD mouse. Annu. Rev. Immunol. 13: 179-200.
4. PHILUPS, T. J., J. C. CRABBE, P. METTEN & J. K. BELKNAP. 1994. Localization of genes affecting alcohol drinking in mice. Alcohol Clin. Exp. Res. 18: 931-941.
5. RODRIGUES, L. A., R. PLOMIN, D. A. BLIZARD, B. C. JONES & G. E. MCCLEARN. 1995. Alcohol acceptance, preference, and sensitivity in mice. II. Quantitative trait loci mapping analysis using B X D recombinant inbred strains. Alcohol Clin. Exp. Res. 19: 367-373.
6. TARRICONE, B. J., J. N. HINGTGEN, J. K. BELKNAP, S. R. MITCHEL & J. I. NURNBERGER. 1995. Quantitative trait loci associated with behavioral response of B × D recombinant inbred mice to restraint stress: a preliminary communication. Behav. Genet. 25: 489-495.
7. WEST, D. B., L. J. GOUDEY, B. YORK & G. E. TRUETT. 1994. Dietary obesity linked to genetic loci on chromosome 9 and 15 in a polygenic mouse model. J. Clin. Invest. 94: 1410-1416.
8. GALU, J., L. S. Li, A. GLASER, C. G. ÖSTENSON, H. JIAO, H. FAKHRAI, H. J. JACOB, E. S. LANDER & H. LUTHMAN. 1996. Genetic analysis of non-insulin-dependent diabetes mellitus in the GK rat. Nat. Genet. 12: 31-37.
9. GAUGUIER, D., P. FRGUEL, V. PARENT, C. BERNARD, M. T. BIHOREA, B. PORTHA, M. R. JAMES, L. PENICAUD, M. LATHROP & A. KTORZA. 1996. Chromosomal mapping of genetic loci associated with non-insulin-dependent diabetes in the GK rat. Nat. Genet. 12: 38-43.
10. HILBERT, P., K. LlNDPAINTNER, J. S. BECKMANN, T. SERIKAWA, F. SOUBRIER, C. DUBAY, P. CARTWRIGHT, B. DE GOUYON, C. JULIER, S. TAKAHASI, M. VINCENT, D. GANTEN, M. GEORGES & G. M. LATHROP. 1991. Chromosomal mapping of two loci associated with blood-pressure regulation in hereditary hypertensive rats. Nature 353: 521-529.
11. JACOB, H. J., K. LINDPAINTNER, S. E. LINCOLN, K. KUSUMI, R. K. BUNKER, Y. P. MAO, D. GANTEN, V. J. DZAU & E. S. LANDER. 1991. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat. Cell 67: 213-224.
12. IWAI, N. & T. INAOAMI. 1992. Identification of a candidate gene responsible for high blood pressure of spontaneously hypertensive rats. J. Hypertens. 10: 1155-1157.
13. LINDPAINTNER, K., P. HILBERT, D. GANTEN, B. NADAL-GINARD, T. INAGAMI & N. IWAI. 1993. Molecular genetics of the Sa-gene: cosegregation with hypertension and mapping to rat chromosome 1. J. Hypertens. 11: 19-23.
14. DUBAY, C., M. VINCENT, N. J. SAMANI, P. HILBERT, M. A. KAISER, J. P. BERESSI, Y. KOTELEVTSEV, J. S. BECKMANN, F. SOUBRIER, J. SASSARD & G. M. LATHROP. 1993. Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats. Nat. Genet. 3: 354-357.
15. SAMANI, N. J., D. LODWICK, M. VINCENT, C. DUBAY, M. A. KAISER, M. P. KELLY, M. Lo, J. HARRIS, J. SASSARD, M. LATHROP & J. D. SWALES. 1993. A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure. J. Clin. Invest. 92: 1099-1103.
16. BIANCHI, G., G. TRIPODI, G. CASARI, S. SALARDI, B. R. BARBER, R. GARCIA, P. LEONI, L. TORIELU, D. Cusi, M. FERRANDI, L. A. PINNA, F. E. BARALLE & P. FERRARI. 1994. Two point mutations within the adducin genes are involved in blood pressure variation. Proc. Nail. Acad. Sci. U.S.A. 91: 3999-4003.
17. DENG, A. Y., H. DENE, M. PRAVENECE & J. P. RAPP. 1994. Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes. J. Clin. Invest. 93: 2701-2709.
18. JACKSON, R. A., J. B. BUSE, R. RJFAI, D. PELLETIER, E. L. MILFORD, C. B. CARPENTER, G. S. EISENBARTH & R. M. WILLIAMS. 1984. Two genes required for diabetes in BB rats: evidence from cyclical intercrosses and backcrosses. J. Exp. Med. 159: 1629-1636.
19. KLÖTING, I. & O. STARK. 1987. Genetic studies of IDDM in BB rats: the incidence of diabetes in F2 and first backcross hybrids allows rejection of a recessive hypothesis. Exp. Clin. En-, docrinol. 98: 312-318.
20. KLÖTING, I. & L. VOGT. 1990. Coat colour phenotype, leucopenia, and insulin-dependent diabetes mellitus (IDDM) in BB rats. Diabetes Res. 15: 37-39.
21. JACOB, H. J., A. PETTERSSON, D. WILSON, Y. MAO, A. LERNMARK & E. S. LANDER. 1992. Genetic dissection of autoimmune type I diabetes in the BB rat. Nat. Genet. 2: 56-60.
22. Louis, W. J., R. TABEI, A. SJOERDSMA & S. SPECTOR. 1969. Inheritance of high blood pressure in the spontaneously hypertensive rat. Lancet 1: 1035-1036.
23. KNUDSEN, K. D., L. K. DAHL, K. THOMPSON, J. IWAI, M. HEINE & G. LEITL. 1970. Effects of chronic excess salt ingestion: inheritance of hypertension in the rat. J. Exp. Med. 132:976-1000.
24. TANASE, H., Y. SUZUKI, A. OOSHIMA, Y. YAMORI & K. OKAMOTO. 1970. Genetic analysis of blood pressure in spontaneously hypertensive rats. Jpn. Circ. J. 34: 1197-1212.
25. TANASE, H. 1979. Genetic control of blood pressure in spontaneously hypertensive rats (SHR). Jikken Dobutsu 28: 519-530.
26. OKAMOTO, K. 1972. Spontaneous Hypertension, Ist Pathogenesis und Comuplications. SpringerVerlag. Berlin/New York.
27. YEN, T. T., P. L. Yu, H. ROEDER & P. W. WILLARD. 1974. A genetic study of hypertension in Okamoto-Aoki spontaneously hypertensive rats. Heredity 33: 309-316.
28. SCHLAGER, G. 1972. Spontaneous hypertension in laboratory animals. J. Hered. 63: 35-38.
29. KLÖTING, I. & L. VOGT. 1991. BB/O(ttawa)K(arlsburg) rats: features of a subline of diabetesprone BB rats. Diabetes Res. 18: 79-87.
30. KLÖTING, I., M. STIELOW & L. VOGT. 1995. Development of new animal models in diabetes research: spontaneously hypertensive-diabetic rats. Diabetes Res. 29: 127-138.
31. KLÖTING, I., L. VOGT & T. SERIKAWA. 1995. Locus on chromosome 18 cosegregates with diabetes in the BB/OK subline. Diabetes Metab. 21: 338-344.
32. HAMET, P., Y. L. SUN, D. MALO, D. KONG, V. KREN, M. PRAVENEC, J. KUNES, P. DUMAS, L. RICHARD, F. GAGNON & J. TREMBLAY. 1994. Genes of stress in experimental hypertension. Clin. Exp. Pharmacol. Physiol. 21: 907-911.
33. KLÖTING, I.,B. VOIGT & L. VOGT. 1995. Forty-seven polymorphic microsatellite loci in different inbred rat strains. J. Exp. Anim. Sci. 37: 42-47.
34. LANDER, E. S., P. GREEN, J. ABRAHAMSON, A. BARLOW, M. J. DALY, S. E. LINCOLN & L. NEWBURG. 1987. MAPMAKER: an interactive computer package for constructing genetic linkage maps of experimental and natural populations. Genomics 1: 174-181.
35. LANDER, E. S. & D. BOTSTEIN. 1989. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121: 185-199.
36. BERG, S., A. DUNGER, L. VOGT, I. KLÖTING & S. SCHMIDT. 1996. Circadian variations in blood pressure and heart rate in diabetes-prone and resistant rat strains compared with spontaneously hypertensive rats. Exp. Clin. Endocrinol. Diabetes. In press.
37. KLÖTING, I. & K. REIHER. 1985. Einige Aspekte zur Haltung und Reproduktion spontandiabetischer BB-Ratten. Z. Verstierkd. 27: 5-11.