Fungal riboflavin 5'-hydroxymethyl dehydrogenase catalyzes formation of both the aldehyde (riboflavinal) and the acid (riboflavinoic acid)

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1342, Issue 2, 1997, Pages 116-118

  Chen, Haoyuan ^a   McCormick, Donald B ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B2 Acid (riboflavinoic acid); B2 Aldehyde (riboflavinal); Riboflavin 5' hydroxymethyl dehydrogenase; Riboflavin side chain oxidation; Schizoflavin

Indexed keywords

OXIDOREDUCTASE; RIBOFLAVIN; RIBOFLAVIN DERIVATIVE; RIBOFLAVINAL; RIBOFLAVINOIC ACID; SCHIZOFLAVIN; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; PRIORITY JOURNAL; REACTION ANALYSIS; SCHIZOPHYLLUM COMMUNE; SHORT SURVEY; VITAMIN METABOLISM;

SCHIZOPHYLLUM COMMUNE;

EID: 0030690991     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(97)00121-0     Document Type: Article

References (7)

1. J.L. Chastain, D.B. McCormick, Flavin metabolites, in: F. Muller (Ed.), Chemistry and Biochemistry of Flavoenzymes, Vol. 1. CRC Press, Boca Raton, 1990, pp. 195-200.
2. S. Tachibana, T. Murakami, Isolation and identification of schizoflavins, in: D.B. McCormick, L.D. Wright (Eds.), Vitamins and Coenzymes, Methods in Enzymology, Vol. 66, Part E, Academic Press, New York, 1980, pp. 333-338.
3. 2-aldehyde-forming enzyme in Schizophyllum commune. J. Biol. Chem. 256:1981;6682-6685.
4. 2-aldehyde forming enzyme from Schizophyllum commune. Arch. Biochem. Biophys. 315:1994;100-103.
5. H. Chen, D.B. McCormick, Riboflavin 5′-hydroxymethyl oxidation: molecular cloning, expression, and glycoprotein nature of the 5′-aldehyde-forming enzyme from Schizophyllum commune, J. Biol. Chem. (1997) in press.
6. C. Walsh, Enzyme Reaction Mechanisms, W.H. Freeman, San Francisco, 1979.
7. 2-aldehyde-forming enzyme from Schizophyllum commune. J. Label. Compd. Radiopharm. 36(10):1995;953-960.