A bioactive 60-kilodalton prolactin species is preferentially secreted in cultures of mitogen-stimulated and nonstimulated peripheral blood mononuclear cells from subjects with systemic lupus erythematosus

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 11, 1997, Pages 3664-3669

  Larrea, Fernando ^a   Martínez Castillo, Araceli ^a   Cabrera, Victor ^a   Alcocer Varela, Jorge ^a   Queipo, Gloria ^a   Cariño, Cecilia ^a   Alarcón Segovia, Donato ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISERUM; COMPLEMENTARY DNA; CONCANAVALIN A; MITOGENIC AGENT; POLYCLONAL ANTIBODY; PROLACTIN;

ADOLESCENT; ADULT; ARTICLE; CELL GROWTH; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LYMPHOMA CELL; MONONUCLEAR CELL; PRIORITY JOURNAL; PROLACTIN RELEASE; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0030690157     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.11.3664     Document Type: Article

References (48)

1. Nagy E, Berczi I. 1978 Immunodeficiency in hypophysectomized rats. Acta Endocrinol (Copenh). 89:530-537.
2. Gala RR. 1991 Prolactin and growth hormone in the regulation of the immune system. Proc Soc Exp Biol Med. 198:513-527.
3. Berczi I. 1989 Immunoregulation by neuroendocrine factors. Dev Comp Immunol. 13:329-341.
4. Brenton EW, Meltzer MS, Holaday JW. 1988 Suppression of macrophage activation and T-lymphocyte function in hyperprolactinemic mice. Science. 239:401-404.
5. Nicoletti I, Gerli R, Orlandi S, Migliorati G, Rambott P, Riccardi C. 1989 Defective natural-killer cell activity in puerperal hyperprolactinemia. J Reprod Immunol. 15:113-121.
6. Vidaller A, Guadarrama F, Llorente L, et al. 1992 Hyperprolactinemia inhibits natural killer (NK) cell function in vivo and its bromocriptine treatment not only corrects it but makes it more efficient. J Clin Immunol. 12:210-215.
7. Hiestand PC, Mekler P, Nordmann R, Grieder A, Permmongkol C. 1986 Prolactin as a modulator of lymphocyte responsiveness provides a possible mechanism of action for cyclosporine. Proc Natl Acad Sci USA. 83:2599-2603.
8. Bernton E, Bryant H, Holaday J, Jitendra D. 1992 Prolactin and prolactin secretagogues reverse immunosuppression in mice treated with cysteamine, glucocorticoids or cyclosporin-A. Brain Behav Immunol. 6:394-408.
9. Berczi I, Nagy E. 1986 Prolactin and other lactogenic hormones. In: Berczi I, ed. Pituitary function and immunity. Boca Raton: CRC Press; 161-183.
10. Gout PW, Beer CT, Noble RL. 1980 Prolactin stimulated growth of cell cultures established from malignant Nb2 rat lymphomas. Cancer Res. 40:2433-2436.
11. Tanaka T, Shiu RPC, Gout PW, Beer CT, Noble RL, Friesen HG. 1980 A new sensitive and specific bioassay for lactogenic hormone measurement of prolactin and growth hormone in human serum. J Clin Endocrinol Metab. 51:1058-1063.
12. Esquifino AI, Villanua MA, Szary A, Yau J, Bartke A. 1991 Ectopic pituitary transplants restore immunocompetence in Ames dwarf mice. Acta Endocrinol (Copenh). 125:67-72.
13. Russell DH, Mills KT, Talamantes FJ, Bern HA. 1988 Neonatal administration of prolactin antiserum alters the developmental pattern of T- and B-lymphocytes in the thymus and spleen of BALB/c female mice. Proc Natl Acad Sci USA. 87:7404-7407.
14. Russell DH, Kibler R, Matrisian L, Larson DF, Poulos B, Magun BE. 1985 Prolactin receptors on human T and B lymphocytes-antagonism of prolactin binding by cyclosporine. J Immunol. 134:3027-3031.
15. Bellussi C, Mucciolli G, Ghe C, Di Carlo R. 1987 Prolactin binding sites in human erythrocytes and lymphocytes. Life Sci. 41:951-959.
16. Matera L, Mucciolli G, Cesano A, Bellussi G, Genazzani E. 1988 Prolactin receptors on large granular lymphocytes: dual regulation by cyclosporin A. Brain Behav Immun. 2:1-10.
17. Pellegrini I, Lebrun JJ, Ali S, Kelly PA. 1992 Expression of prolactin and its receptor on human lymphoid cells. Mol Endocrinol. 6:1023-1029.
18. O'Neal KD, Schwarz LA, Yu-Lee LY. 1991 Prolactin receptor gene expression in lymphoid cells. Mol Cell Endocrinol. 82:127-135.
19. Bazan JF. 1990 Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA. 87:6934-6938.
20. Hartmann DP, Holaway JW, Brenton EW. 1989 Inhibition of lymphocyte proliferation by antibodies to prolactin. FASEB J. 3:2194-2201.
21. Montgomery DW, Zukoski CF, Shah GN, Buckley AR, Pacholczyk T, Russell DH. 1987 Concanavalin A-stimulated murine splenocytes produce a factor with prolactin-like bioactivity and immunoreactivity. Biochem Biophys Res Commun. 145:692-698.
22. Vidaller A, Llorente L, Larrea F, Méndez JP, Alcocer-Varela J, Alarcón-Segovia D. 1986 T cell dysregulation in patients with hyperprolactinemia: effect of bromocriptine treatment. Clin Immunol Immunopathol. 38:337-343.
23. Gerli C, Riccardi C, Nicoletti I, et al. 1987 Phenotypic and functional abnormalities of T lymphocytes in pathological hyperprolactinemia. J Clin Immunol. 7:463-470.
24. Gerli C, Rambotti P, Nicoletti I, Orlandi S, Migliorati C, Riccardi C. 1986 Reduced number of natural killer cells in patients with pathological hyperprolactinemia. Clin Exp Immunol. 64:399-406.
25. Jara LJ, Lavalle C, Espinoza LR. 1992 Does prolactin have a role in the pathogenesis of systemic lupus erythematosus? J Rheumatol. 19:1333-1336.
26. Petri M, Howard D, Repke J. 1991 Frequency of lupus flare in pregnancy. The Hopkins Lupus Pregnancy Center experience. Arthritis Rheumatol. 34:1538-1545.
27. McMurray R, Keisler D, Knuckel K, Izui S, Walker SE. 1991 Prolactin influences autoimmune disease activity in the female B/W mouse. J Immunol. 147:3780-3787.
28. Tan EM, Cohen AS, Fries JF, et al. 1982 The revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1271-1277.
29. Guzmán J, Cardiel MH, Arce-Salinas A, Sánchez-Guerrero J, Alarcón-Segovia D. 1992 Meassurement of disease activity in systemic lupus erythematosus. Prospective validation of 3 clinical indices. J Rheumatol. 19:1551-1558.
30. Boyum A. 1968 Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest. 21:77-98.
31. Chomczynski P, Sacchi N. 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:156-159.
32. Maniatis T, Jeffrey A, van de Sande H. 1975 Chain length determination of small double and single-stranded DNA molecules by polyacrylamide gel electrophoresis. Biochemistry. 14:3787-3794.
33. Cooke NE, Coit D, Shine J, Baxter JD, Martial JA. 1981 Human prolactin, cDNA structural analysis and evolutionary comparisons. J Biol Chem. 256:4007-4016.
34. Larrea F, Méndez I, Parra A, Espinoza de los Monteros A. 1993 Serum pattern of different molecular forms of prolactin during normal human pregnancy. Hum Reprod. 8:1617-1622.
35. Laemmli UK. 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:680-685.
36. Towbin H, Stachelin T, Gordon J. 1970 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA. 76:4350-4356.
37. Larrea F, Sandoval JL, Salinas E, Franco-Rodríguez VA, Méndez I, Ulloa-Aguirre A. 1995 Evidence for an altered luteinizing hormone sensitivity to naloxone in pathological hyperprolactinaemia. Clin Endocrinol (Oxf). 43:591-600.
38. Berczi I. 1993 Prolactin, pregnancy and autoimmune disease. J Rheumatol. 20:1095-1100.
39. Clevenger CV, Russel DH, Appassamy PM, Prystowsky MB. 1990 Regulation of interleukin-2 driven T lymphocytes proliferation by prolactin. Proc Natl Acad Sci USA. 87:6460-6464.
40. Gouilleux F, Moritz D, Humar M, Moriggl R, Berchtold S, Groner B. 1995 Prolactin and interleukin-2 receptor in T lymphocytes signal through a MGF-STAT5-like transcription factor. Endocrinology. 136:5700-5708.
41. Gutiérrez MA, Molina JF, Jara LJ, et al. 1996 Prolactin-induced immunoglobulin and autoantibody production by peripheral blood mononuclear cells from systemic lupus erythematosus and normal individuals, Int Arch Allergy Immunol. 109:229-235.
42. Sabharwal P, Glaser R, Lafuse W, et al. 1992 Prolactin synthesized and secreted by human peripheral blood mononuclear cells: an autocrine growth factor for lymphoproliferation. Proc Natl Acad Sci USA. 89:7713-7716.
43. Jara LJ, Goméz-Sánchez C, Silveira LH, Martínez-Ojuna F, Espinoza LR. 1992 Hyperprolactinemia in systemic lupus erythematosus: association with disease activity. Am J Med Sci. 303:222-226.
44. Gutiérrez MA, Molina JF, Jara LJ, et al. 1995 Prolactin and systemic lupus erythematosus: prolactin secretion by SLE lymphocytes and proliferation (autocrine) activity. Lupus. 4:348-352.
45. Sinha YN. 1995 Structural variants of prolactin: occurrence and physiological significance. Endocr Rev. 16:354-369.
46. Montgomery DW, LeFevre JA, Ulrich ED, Adamson CR, Zukoski CF. 1990 Identification of prolactin-like proteins synthesized by normal lymphocytes. Endocrinology. 127:2601-2603.
47. Bates LG, Grove DS, Mastro AM. 1995 Mechanisms of activation and suppression in rat Nb2 cells: a model for interactions between prolactin and the immune system. Exp Cell Res. 218:567-572.
48. Gagnerault M-C, Touraine P, Savino W, Kelly PA, Dardenne M. 1993 Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations. J Immunol. 150:5673-5681.