Silver-stained nucleolar organizer regions in hypertrophic and keloid scars

American Journal of Dermatopathology

Volumn 19, Issue 5, 1997, Pages 468-472

  Ghazizadeh, Mohammad ^a   Miyata, Nariaki ^b   Sasaki, Yoshihiro ^a   Arai, Katsuyuki ^b   Aihara, Kaoru ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Collagen; Fibroblasts; Histology; Hypertrophic scar; Keloid scar; Silver stained nucleolar organizer regions

Indexed keywords

ARTICLE; CELL PROLIFERATION; CHROMOSOME NOR; HISTOLOGY; HUMAN; HUMAN TISSUE; HYPERTROPHIC SCAR; IMMUNOHISTOCHEMISTRY; KELOID; PRIORITY JOURNAL; SKIN FIBROBLAST; WOUND HEALING;

ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; CELL DIVISION; CELL NUCLEUS; CICATRIX, HYPERTROPHIC; COLLAGEN; COLORING AGENTS; CONNECTIVE TISSUE; FIBROBLASTS; HUMANS; KELOID; MICROSCOPY, ELECTRON; NUCLEOLUS ORGANIZER REGION; RETROSPECTIVE STUDIES; SILVER NITRATE; SKIN;

EID: 0030685110     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000372-199710000-00006     Document Type: Article

References (23)

1. Rockwell WB, Cohen IK, Ehrlich HP. Keloids and hypertrophic scars: a comprehensive review. Plast Reconstr Surg 1989;84:827- 37.
2. Lawrence WT. In search of the optimal treatment of kefoids: report of a series and review of the literature. Ann Plast Surg 1991;27:164-78.
3. Blackburn WR, Cosman B. Histologic basis of keloid and hypertrophic scar differentiation. Arch Pathol 1966;82:65-71.
4. Liarrabee WF Jr, Bolen JW, Sutton D. Myofibroblasts in head and neck surgery. An experimental and clinical study. Arch Otolaryngol Head Neck Surg 1986;114:982-6.
5. Mattsuoka LY, Uitto J, Wortsman J, et al. Ultrastructure of keloid fibroblasts. Am J Dermatopathol 1988;10:505-8.
6. Ehrlich HP, Desmouliere A, Diegelmann RF, et al. Morphological and immunochemical differences between keloid and hypertrophic scar. Am J Pathol 1994;45:105-13.
7. Janssen de Limpens AMP, Connane RH. Studies on the immunologic aspects of keloids and hypertrophic scars. Arch Dermatol Res 1982;274:259-66.
8. Fakan S, Hernandez-Verdun D. The nucleous and the nucleolar organizer regions. Biol Cell 1986;56:184-206.
9. Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ. Improvement in the staining and in the visualiztion of the argyrophilic proteins of the nueleolar organizer region at the optical level, Histochem J 1986;18:5-14.
10. Crocker J, Nar P. Nucleolar organizer regions in lymphoma. J Pathol 1987;151:111-8.
11. Hubbell HR, Lau Y-F, Brown RL, Hsu TC. Cell cycle analysis and drug inhibition studies of silver in synchronous HeLa cells. Exp Cell Res 1980;129:139-47.
12. Hubbell HR. Silver staining as an indicator of active ribosomal genes. Stain Technol 1985:60:285-94.
13. Kacerovska H, Likovsky Z, Smetana K. Nuclecolar silver stained granules in Yoshida sarcoma cells after RNA synthesis inhibition. Neoplasma 1981;28:513-6.
14. Giri DD, Nothinham JF, Lawry J, Dundas SAC, Underwod JCE, Silver-binding nucleolar organizer regions (AgNORs) in benign and malignant breast lesions: correlations with ploidy and growth phase by DNA flow cytometry. J Pathol 1989;157:307-13.
15. Ghazizadeh M, Sasaki Y, Oguto T, Aihara K. Silver staining of nucleolar organizer regions in prostatic lesions. Histopathology 1991;19:369-72.
16. Delahunt B, Ribas JL, Nacey JN, Bethwaite PB. Nucleolar organizer regions and in cell carcinoma. J Pathol 1991;163:31-7.
17. Mourad WA, Setrakian S, Hales ML, Abdulla M, Trucco G. The argyrophilic nucleolar organizer regions in ductal carcinoma in situ of the breas. Cancer 1994;74:1739-45.
18. Crocker J, MacCartney JC, Smith PJ. Correlation DNA flow cytometric and nucleolar organizer regions data in non- Hodgkin Iymphomas. J Pathol 1981;154:151-6.
19. Cohen MB, Waldmen FM, Carroll PR, et al. Comparision of five histopathologic methods to assess cellular proliferation in transitional cell carcinoma of the urinary bladder. Hum Pathol 1993;24:772-8.
20. Nielson AL, Nyholm HCJ, Expression of MIB-1 (paraffin ki-67) and AgNOR morphology in endometrial adenocarcinomas of endometnroid type. Int J Gynecol Pathol 1994;13:37-44.
21. Ghazizadeh M, Sasaki Y, Araki T, Konishi H, Aihara K. Prognostic value of proliferative activity of ovarian carcinoma is revealed by PCNA and AgNOR analyses. Am J Clin Pathol 1997;451-8.
22. Other D, Riedraann B, Maier H, et al. Standardized staining and analysis of argyrophilic nucleolar organizer region associated proteins (AgNORs) in radically resected colorectal adenocarcinomacorrelation with tumor stage and long-term survival. J Pathol 1995;175:441-8.
23. Nakaoka H, Miyauchi S, Miki Y. Proliferating activity of dermal fibroblasts in keloids and hypertrophic scars. Acta Dermatopathol Venereol 1995;75:102-4.