MspI restriction fragment length polymorphism at the glycoprotein hormone α-subunit locus. Association of certain genotypes with neoplasia

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1354, Issue 1, 1997, Pages 83-96

  Cox, G Stanley ^a   Cosgrove, Dominic E ^a   Haas, Michael J ^a   Stiles, Warren ^a   McIntosh, David G ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Choriogonadotropin; Chromosome 6; RFLP

Indexed keywords

ALLELE; ALPHA CHAIN; ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; CHROMOSOME 6; DNA STRUCTURE; GENE FREQUENCY; GENE LOCUS; GENOTYPE; MALIGNANT TRANSFORMATION; NONHUMAN; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

DEOXYRIBONUCLEASE HPAII; FEMALE; GENOTYPE; GERM-LINE MUTATION; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; HUMANS; MALE; NEOPLASMS; PEDIGREE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030684015     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(97)00098-5     Document Type: Article

References (52)

1. Daniels-McQueen S., McWilliams D., Birken S., Canfield R., Landefeld T., Boime I. Identification of mRNAs encoding the α and β subunits of human choriogonadotropin. J. Biol. Chem. 253:1978;7109-7114.
2. Boothby M., Ruddon R.W., Anderson C., McWilliams D., Boime I. A single gonadotropin α-subunit gene in normal tissue and tumor-derived cell lines. J. Biol. Chem. 256:1981;5121-5127.
3. Fiddes J.D., Goodman H.M. The gene encoding the common alpha subunit of the four human glycoprotein hormones. J. Mol. Appl. Genet. 1:1981;3-18.
4. Boorstein W.R., Vamvakopoulos N.C., Fiddes J.C. Human chorionic gonadotropin β-subunit is encoded by at least eight genes arranged in tandem and inverted pairs. Nature. 300:1982;419-423.
5. Policastro P., Ovitt C.E., Hoshina M., Fukuoka H., Boothby M.R., Boime I. The β-subunit of human chorionic gonadotropin is encoded by multiple genes. J. Biol Chem. 258:1983;11492-11499.
6. Talmadge K., Boorstein W.R., Fiddes J.C. The human genome contains seven genes for the beta-subunit of chorionic gonadotropin but only one gene for the beta subunit of luteinizing hormone. DNA. 2:1983;281-289.
7. W.D. Odell and A. Wolfsen, Etiology: Viral carcinogenesis, in: F.F. Becker (Ed.), Cancer, vol. 3, New York, Plenum Press, 1975, pp. 81-93.
8. Blackman M.R., Rosen S.W., Weintraub B.D. Ectopic Hormones. Adv. Int. Med. 23:1978;85-113.
9. Chou J.Y., Robinson J.C., Wang S.S. Effects of sodium butyrate on synthesis of human chorionic gonadotropin in trophoblastic and nontrophoblastic tumors. Nature. 268:1977;543-544.
10. Hussa R.O., Pattillo R.A., Ruckert A.C.F., Scheuermann K.W. Effects of butyrate and dibutyryl cyclic AMP on hCG-secreting trophoblastic and non-trophoblastic cells. J. Clin. Endocrinol. Metab. 46:1978;69-76.
11. Ruddon R.W., Anderson C., Meade-Cobun K.S. Stimulation of synthesis and secretion of chorionic gonadotropin subunits by eutopic and ectopic hormone-producing human cell lines. Cancer Res. 40:1980;4519-4523.
12. Campain J.A., Eudy J.D., Cox G.S. Permissive effect of cyclic AMP and cycloheximide for induction by sodium butyrate of the glycoprotein hormone α-subunit gene in choriocarcinoma cells. Cell Growth Diff. 5:1994;827-838.
13. Fein H.G., Rosen S.W., Weintraub B.D. Increased glycosylation of serum human chorionic gonadotropin and subunits from eutopic and ectopic sources: Comparison with placental and urinary forms. J. Clin. Endocrinol. Metab. 50:1980;1111-1120.
14. Cole L.A., Perini F., Birken S., Ruddon R.W. An oligosaccharide of the O-linked type distinguishes the free from the combined form of hCG α-subunit. Biochem. Biophys. Res. Commun. 122:1984;1260-1267.
15. Cox G.S., McClure D.S., Cosgrove D.E. Dual effects of 2-deoxyglucose on synthesis of the glycoprotein hormone common α-subunit in butyrate-treated HeLa cells. Mol Cell. Biol. 7:1987;1592-1601.
16. Cox G.S. Phosphorylation of the glycoprotein hormone α-subunit secreted by human tumor cell lines. Biochem. Biophys. Res. Commun. 140:1986;143-150.
17. Saccuzzo J.E., Krzesicki R.F., Perini F., Ruddon R.W. Phosphorylation of the secreted, free α-subunit of human chorionic gonadotropin. Proc. Natl. Acad. Sci. USA. 83:1986;9493-9496.
18. Hainsworth J.D., Greco F.A. Human chorionic gonadotropin production by colon carcinoma. Cancer. 56:1985;1337-1340.
19. Wong D.T.W., Hartigan J.A., Biswas D.K. Mechanism of induction of human chorionic gonadotropin in lung tumor cells in culture. J. Biol. Chem. 259:1984;10738-10744.
20. Goelz S.E., Vogelstein B., Hamilton S.R., Feinberg A.P. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science. 228:1985;187-190.
21. Stanbridge E.J., Rosen S.W., Sussman H.S. Expression of the α-subunit of human chorionic gonadotropin is specifically correlated with tumorigenic expression in human cell hybrids. Proc. Natl. Acad. Sci USA. 79:1982;6242-6245.
22. Kellen J.A., Wong A., Gardner H.A., Raikow R.B., Acevedo H.F. Expression of hCG-like material correlates with invasive phenotype of R3230 rat carcinoma. Proc. Ann. Meet. Am. Assoc. Cancer Res. 27:1986;57.
23. Rivera R.T., Pasion S.G., Wong D.T., Fei Y., Biswas D.K. Loss of tumorigenic potential by human lung tumor cells in the presence of antisense RNA specific to the ectopically synthesized alpha subunit of human chorionic gonadotropin. J. Cell Biol. 108:1989;2423-2434.
24. Kumar S., Talwar G.P., Biswas D.K. Necrosis and inhibition of growth of human lung tumor by anti-α-human chorionic gonadotropin antibody. J. Natl. Cancer Inst. 84:1992;42-47.
25. Acevedo H.F., Tong J.Y., Hartsock R.J. Human chorionic gonadotropin-beta subunit gene expression in cultured human fetal and cancer cells of different types and origins. Cancer. 76:1995;1467-1475.
26. Southern E.M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:1975;503-517.
27. Fiddes J.C., Goodman H.M. Isolation, cloning and sequence analysis of the α-subunit cDNA of human chorionic gonadotropin. Nature. 281:1979;351-356.
28. Cosgrove D.E., Campain J.A., Cox G.S. Chorionic gonadotropin synthesis by human tumor cell lines: examination of subunit accumulation, steady-state levels of mRNA, and gene structure. Biochim. Biophys. Acta. 1007:1989;44-54.
29. Dracopoli N.C., Houghton A.N., Old L.J. Loss of polymorphic restriction fragments in malignant melanoma: Implications for tumor heterogeneity. Proc. Natl. Acad. Sci. U.S.A. 82:1985;1470-1474.
30. Hoshina M., Boothby M.R., Hussa R.D., Pattillo R.A., Camel H.M., Boime I. Segregation patterns of polymorphic restriction sites of the gene encoding the α-subunit of human chorionic gonadotropin in trophoblastic disease. Proc. Natl. Acad. Sci. USA. 81:1984;2504-2507.
31. Keshet F., Cedar H. Effect of CpG methylation on MspI. Nucleic Acids Res. 11:1983;3571-3580.
32. Walder R.Y., Langtimm C.J., Chatterjee R., Walder J.A. Cloning of the MspI modification enzyme: the site of modification and its effect on cleavage by MspI and HpaII. J. Biol. Chem. 258:1983;1235-1241.
33. Trent J.M., Salmon S.E. Karyotypic analysis of human ovarian carcinoma cells cloned in short term agar culture. Cancer Genet. Cytogenet. 3:1981;279-291.
34. Trent J.M., Rosenfeld S.B., Meyskens F.L. Chromosome 6q involvement in human malignant melanoma. Cancer Genet. Cytogenet. 9:1983;177-180.
35. J.M. Trent, Cloning of human tumor stem cells, in: S.E. Salmon (Ed.), Progress in Clinical and Biological Research, New York, A. Liss, 1980, pp. 165-177.
36. A.A. Sandberg, in: The chromosomes in human cancer and leukemia, New York, Elsevier, 1980, pp. 458-558.
37. Dracopoli N.C., Alhadeff B., Houghton A.N., Old L.J. Loss of heterozygosity at autosomal and X-linked loci during tumor progression in a patient with melanoma. Cancer Res. 47:1987;3995-4000.
38. Satya-Prakash K.L., Pathak S., Hsu T.C., Olive M., Cailleau R.A. Human breast adenocarcinoma with chromosome and isoenzyme markers similar to those of the HeLa line. J. Natl. Cancer Inst. 62:1979;263-271.
39. Mullokandov M.R., Kholodilov N.G., Atkin N.B., Burk R.D., Johnson A.B., Klinger H.P. Genomic alterations in cervical carcinoma: losses of chromosome heterozygosity and human papilloma virus tumor status. Cancer Res. 56:1996;197-205.
40. Honchel R., McDonnell S., Schaid D.J., Thibodeau S.N. Tumor necrosis factor-α allelic frequency and chromosome 6 allelic imbalance in patients with colorectal cancer. Cancer Rev. 56:1996;145-149.
41. Yunis J.J. The chromosomal basis of human neoplasia. Science. 221:1983;227-236.
42. Cavenee W.K., Dryja T.P., Phillips R.A., Benedict W.F., Godbout R., Gallie B.L., Murphree A.L., Strong L.C., White R.L. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature. 305:1983;779-784.
43. Dalla-Favera R., Martinotti S., Gallo R.C., Erikson J., Croce C.M. Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas. Science. 219:1983;963-966.
44. ar-Rushdi A., Mishikura K., Erikson J., Watt R., Rovera G., Croce C.M. Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma. Science. 222:1983;390-393.
45. Heisterkamp N., Stephenson J.R., Groffen J., Hansen P.F., deKlein A., Bartram C.R., Grosveld G. Localization of the c-abl oncogene adjacent to a translocation breakpoint in chronic myelocytic leukemia. Nature. 306:1983;239-241.
46. Ha proto-oncogenes in cancers are frequent and show clinical correlation. Science. 231:1986;261-264.
47. Stanbridge E.J., Flandermeyer R.R., Daniels D.W., Nelson-Rees W.A. Specific chromosome loss associated with the expression of tumorigenicity in human cell hybrids. Somat. Cell Genet. 7:1981;699-712.
48. O'Hara B.M., Klinger H.P., Curran T., Zhang Y.D., Blair D.G. Levels of fos, ets-2 and myb proto-oncogene RNAs correlate with segregation of chromosome 11 of normal cells and with suppression of tumorigenicity. Mol. Cell. Biol. 7:1987;2941-2946.
49. Busslinger M., de Boer E., Wright S., Grosveld F.F., Flavell R.A. The sequence of GGCmCGG is resistant to MspI cleavage. Nucleic Acids Res. 11:1983;3559-3569.
50. Cox G.S., Cosgrove D.E., Sullivan T.T., Haas M.J. Induction by cycloheximide of the glycoprotein hormone α-subunit gene in human tumor cell lines and identification of a possible negative regulatory factor. J. Biol. Chem. 265:1990;13190-13197.
51. Gusella J.F. DNA polymorphism and human disease. Ann. Rev. Biochem. 55:1986;831-854.
52. Waalwijk C., Flavell R.A. MspI, an isoschizomer of HpaII which cleaves both unmethylated and methylated HpaII sites. Nucleic Acids Res. 5:1978;3231-3236.