Islet amyloid polypeptide and calcitonin gene-related peptide expression are upregulated in lumbar dorsal root ganglia after unilateral adjuvant-induced inflammation in the rat paw

Molecular Brain Research

Volumn 50, Issue 1-2, 1997, Pages 127-135

  Mulder, Hindrik ^a   Zhang, Yanzhen ^a   Danielsen, Nils ^a   Sundler, Frank ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Amylin; Freund's complete adjuvant; Gene expression; Hybridization, in situ; Inflammation; Monarthritis

Indexed keywords

ADJUVANT; AMYLOID PROTEIN; CALCITONIN GENE RELATED PEPTIDE; MESSENGER RNA; NEUROPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE INDUCTION; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; NERVE CELL; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; SPINAL CORD DORSAL HORN; SPINAL GANGLION; TISSUE DISTRIBUTION;

AMYLOID; ANIMALS; BODY WEIGHT; CALCITONIN GENE-RELATED PEPTIDE; FEMALE; FREUND'S ADJUVANT; GAIT; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; LUMBOSACRAL REGION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; TARSUS, ANIMAL; UP-REGULATION;

ANIMALIA;

EID: 0030682160     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00178-2     Document Type: Article

References (34)

1. P.J. Barnes, M.G. Belvisi, D.F. Rogers. Modulation of neurogenic inflammation: novel approaches to inflammatory disease, Trends Pharmacol. Sci. 11 (1990) 185-189.
2. K. Beaumont, M.A. Kenney, A.A. Young, T.J. Rink, High affinity amylin binding sites in rat brain, Mol. Pharmacol. 44 (1993) 493-497.
3. S.D. Brain, S. Wimalawansa, I. MacIntyre, T.J. Williams, The demonstration of vasodilator activity of pancreatic amylin amide in the rabbit. Am. J. Pathol. 136 (1990) 487-490.
4. S.Y. Chin, J.M. Hall, S.D. Brain, I.K. Morton, Vasodilator responses to calcitonin gene-related peptide (CGRP) and amylin in the rat isolated perfused kidney are mediated via CGRP1 receptors, J. Pharmacol. Exp. Ther. 269 (1994) 989-992.
5. A. Clark, S.B.P. Chargé, M.K. Badman, D.A. MacArthur, E.J.P. deKoning, Islet amyloid polypeptide: actions and role in the pathogenesis of diabetes, Biochem. Soc. Trans. 24 (1996) 594-599.
6. R.E. Coggeshall, H.A. Lekan, Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J. Comp. Neurol. 364 (1996) 6-15.
7. G.J. Cooper, A.C. Willis, A. Clark, R.C. Turner, R.B. Sim, K.B. Reid, Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients, Proc: Natl. Acad. Sci. USA 84 (1987) 8628-8632.
8. L.F. Donaldson, A.J. Harmar, D.S. McQueen, J.R. Seckl. Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat, Mol. Brain Res. 16 (1992) 143-149.
9. L.F. Donaldson, D.S. McQueen, J.R. Seckl, Neuropeptide gene expression and capsaicin-sensitive primary afferents: maintenance and spread of adjuvant arthritis in the rat, J. Physiol. 2 (1995) 473-482.
10. L.F. Donaldson, J.R. Seckl, D.S. McQueen, A discrete adjuvant-induced monoarthritis in the rat: effects of adjuvant dose, J. Neurosci. Methods 49 (1993) 5-10.
11. J. Donnerer, R. Schuligoi, C. Stein, Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: evidence for a regulatory function of nerve growth factor in vivo, Neuroscience 49 (1992) 693-698.
12. G.R. Gerfen, J.F. McGinty, W.S. Young III. Dopamine differentially regulates dynorphin, substance P. and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis, J. Neurosci. 11 (1991) 1016-1031.
13. U. Hanesch, U. Pfrommer, B.D. Grubb, H.G. Schaible, Acute and chronic phases of unilateral inflammation in rat's ankle are associated with an increase in the proportion of calcitonin gene-related peptide-immunoreactive dorsal root ganglion cells, Eur. J. Neurosci. 5 (1993) 154-161.
14. P. Holzer, Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides, Neuroscience 24 (1988) 739-768.
15. B.L. Kidd, S.C. Cruwys, N.E. Garrett, P.I. Mapp, V.A. Jolliffe. D.R. Blake, Neurogenic influences on contralateral responses during experimental rat monoarthritis, Brain Res. 688 (1995) 72-76.
16. C.A. Maggi, A. Meli, The sensory-efferent function of capsaicin-sensitive sensory neurons, Gen. Pharmacol. 19 (1988) 1-43.
17. P.I. Mapp, G. Terenghi, D.A. Walsh, S.T. Chen, S.C. Cruwys, N. Garrett, B.L. Kidd, J.M. Polak, D.R. Blake, Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene-related peptide immunoreactivity in the spinal cord, Neuroscience 57 (1993) 1091-1096.
18. C.R. Morton, W.D. Hutchison, Release of sensory neuropeptides in the spinal cord: studies with calcitonin gene-related peptide and galanin, Neuroscience 31 (1989) 807-815.
19. H. Mulder, A. Leckström, R. Uddman, E. Ekblad, P. Westermark, F. Sundler, Islet amyloid polypeptide (amylin) is expressed in sensory neurons, J. Neurosci. 15 (1995) 7626-7632.
20. H. Mulder, R. Uddman, K. Moller, Y.Z. Zhang, E. Ekblad, J. Alumets, F. Sundler, Pituitary adenylate cyclase activating polypeptide expression in sensory neurons, Neuroscience 63 (1994) 307-312.
21. H. Mulder, Y. Zhang, N. Danielsen, F. Sundler, Islet amyloid polypeptide and calcitonin gene-related peptide expression are downregulated in dorsal root ganglia upon sciatic nerve transection, Mol. Brain Res. 47 (1997) 322-330.
22. R.L. Nahin, M.R. Byers, Adjuvant-induced inflammation of rat paw is associated with altered calcitonin gene-related peptide immuno-reactivity within cell bodies and peripheral endings of primary afferent neurons, J. Comp. Neurol. 349 (1994) 475-485.
23. V. Neugebauer, P. Rumenapp, H.G. Schaible, Calcitonin gene-related peptide is involved in the spinal processing of mechanosensory input from the rat's knee joint and in the generation and maintenance of hyperexcitability of dorsal horn-neurons during development of acute inflammation. Neuroscience 71 (1996) 1095-1109.
24. K. Noguchi, M. De Leon, R.L. Nahin, E. Senba, M.A. Ruda, Quantification of axotomy-induced alteration of neuropeptide mRNAs in dorsal root ganglion neurons with special reference to neuropeptide Y mRNA and the effects of neonatal capsaicin treatment. J. Neurosci. Res. 35 (1993) 54-66.
25. K. Nnguchi, Y. Morita, H. Kiyama. K. Ono, M. Tohyama, A noxious stimulus induces the preprotachykinin-A gene expression in the rat dorsal root ganglion: a quantitative study using in situ hybridization histochemistry. Brain Res. 464 (1988) 31-35.
26. T.D. O'Brien, P.C. Butler, P. Westermark, K.H. Johnson. Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus. Vet. Pathol. 30 (1993) 317-332.
27. H.G. Schaible, Why does an inflammation in the joint hurt?, Br. J. Rheumatol. 35 (1996) 405-406.
28. H.G. Schaible, U. Freudenberger, V. Neugebauer, R.U. Stiller, Intraspinal release of immunoreactive calcitonin gene-related peptide during development of inflammation in the joint in vivo - a study with antibody microprobes in cat and rat. Neuroscience 62 (1994) 1293-1305.
29. H.G. Schaible, B. Jarrott, P.J. Hope, A.W. Duggan, Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: a study with antibody microprobes, Brain Res. 529 (1990) 214-223.
30. D.T. Scott, F.Y. Lam, W.R. Ferrell, Acute joint inflammation-mechanisms and mediators. Gen. Pharmacol. 25 (1994) 1285-1296.
31. J. Szolcsanyi, Antidromic vasodilatation and neurogenic inflammation, Agents Actions 23 (1988) 4-11.
32. E. Weihe, D. Nohr, M.J. Millan, C. Stein, S. Muller, C. Gramsch, A. Herz, Peptide neuroanatomy of adjuvant induced arthritic inflammation in rat, Agents Actions 25 (1988) 255-259.
33. P. Westermark, C. Wernstedt, E. Wilander, D.W. Hayden, T.D. O'Brien, K.H. Johnson, Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc. Natl. Acad. Sci. USA 84 (1987) 3881-3885.
34. P. Westermark, C. Wernstedt, E. Wilander, K. Sletten, A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas. Biochem. Biophys. Res. Commun. 140 (1986) 827-831.