메뉴 건너뛰기




Volumn 27, Issue 5, 1997, Pages 903-911

Changes in expression of CCAAT/enhancer binding protein α (C/EBPα) and C/EBPβ in rat liver after partial hepatectomy but not after treatment with cyproterone acetate

Author keywords

C EBP ; Growth promotion; Hepatectomy; Rats; Transcription factor

Indexed keywords

BINDING PROTEIN; CYPROTERONE ACETATE; DNA; HISTONE H3; MESSENGER RNA; RIBONUCLEASE; TRANSCRIPTION FACTOR;

EID: 0030681238     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80329-7     Document Type: Article
Times cited : (17)

References (47)
  • 1
    • 0001276586 scopus 로고
    • Experimental pathology of the liver 1. Restoration of the liver of the white rat following partial surgical removal
    • Higgins GM, Anderson RM. Experimental pathology of the liver 1. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol. 12:1931;186-202.
    • (1931) Arch Pathol , vol.12 , pp. 186-202
    • Higgins, G.M.1    Anderson, R.M.2
  • 3
    • 0030098001 scopus 로고    scopus 로고
    • Liver regeneration 4: Transcriptional control of liver regeneration
    • Taub R. Liver regeneration 4: transcriptional control of liver regeneration. FASEB J. 10:1996;413-427.
    • (1996) FASEB J , vol.10 , pp. 413-427
    • Taub, R.1
  • 4
    • 0029985372 scopus 로고    scopus 로고
    • Emerging multipotent aspects of hepatocyte growth factor
    • Matsumoto K, Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J Biochem (Tokyo). 119:1996;591-600.
    • (1996) J Biochem (Tokyo) , vol.119 , pp. 591-600
    • Matsumoto, K.1    Nakamura, T.2
  • 5
    • 0029845271 scopus 로고    scopus 로고
    • Liver regeneration versus direct hyperplasia
    • Columbano A, Shinozuka H. Liver regeneration versus direct hyperplasia. FASEB J. 10:1996;1118-1128.
    • (1996) FASEB J , vol.10 , pp. 1118-1128
    • Columbano, A.1    Shinozuka, H.2
  • 6
    • 0030067146 scopus 로고    scopus 로고
    • The antiandrogen cyproterone acetates induces synthesis of transforming growth factor beta 1 in the parenchymal cells of the liver accompanied by an enhanced sensitivity to undergo apoptosis and necrosis without inflammation
    • Oberhammer F, Nagy P, Tiefenbacher R, Froschl G, Bouzahzah B, Thorgeirsson SS, et al. The antiandrogen cyproterone acetates induces synthesis of transforming growth factor beta 1 in the parenchymal cells of the liver accompanied by an enhanced sensitivity to undergo apoptosis and necrosis without inflammation. Hepatology. 23:1996;329-337.
    • (1996) Hepatology , vol.23 , pp. 329-337
    • Oberhammer, F.1    Nagy, P.2    Tiefenbacher, R.3    Froschl, G.4    Bouzahzah, B.5    Thorgeirsson, S.S.6
  • 7
    • 0027310131 scopus 로고
    • Differences in the steady-state levels of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensator regeneration
    • Coni P, Simbula G, de Prati AC, Menegazzi M, Suzuki H, Sarma DS, et al. Differences in the steady-state levels of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensator regeneration. Hepatology. 17:1993;1109-1116.
    • (1993) Hepatology , vol.17 , pp. 1109-1116
    • Coni, P.1    Simbula, G.2    De Prati, A.C.3    Menegazzi, M.4    Suzuki, H.5    Sarma, D.S.6
  • 8
    • 0028146191 scopus 로고
    • Roles of growth factors and of tumor necrosis factor-alpha on liver cell proliferation induced in rats by lead nitrate
    • Shinozuka H, Kubo Y, Katyal SL, Coni P, Ledda-Columbano GM, Columbano A, et al. Roles of growth factors and of tumor necrosis factor-alpha on liver cell proliferation induced in rats by lead nitrate. Lab Invest. 71:1994;35-41.
    • (1994) Lab Invest , vol.71 , pp. 35-41
    • Shinozuka, H.1    Kubo, Y.2    Katyal, S.L.3    Coni, P.4    Ledda-Columbano, G.M.5    Columbano, A.6
  • 9
    • 0024711273 scopus 로고
    • Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein
    • Birkenmeier EH, Gwynn B, Howard S, Jerry J, Gordon JI, Landschulz WH, et al. Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes Dev. 3:1989;1146-1156.
    • (1989) Genes Dev , vol.3 , pp. 1146-1156
    • Birkenmeier, E.H.1    Gwynn, B.2    Howard, S.3    Jerry, J.4    Gordon, J.I.5    Landschulz, W.H.6
  • 10
    • 0026031601 scopus 로고
    • CCAAT-enhancer binding protein: A component of a differentiation switch
    • Umek RM, Friedman AD, McKnight SL. CCAAT-enhancer binding protein: a component of a differentiation switch. Science. 251:1991;288-292.
    • (1991) Science , vol.251 , pp. 288-292
    • Umek, R.M.1    Friedman, A.D.2    McKnight, S.L.3
  • 11
    • 0026611673 scopus 로고
    • IL-6 and NF-IL6 in acute-phase response and viral infection
    • Akira S, Kishimoto T. IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol Rev. 127:1992;25-50.
    • (1992) Immunol Rev , vol.127 , pp. 25-50
    • Akira, S.1    Kishimoto, T.2
  • 12
    • 0024046156 scopus 로고
    • Isolation of a recombinant copy of the gene encoding C/EBP [published erratum appears in Genes Dev 1994 May 1;8(9):1131]
    • Landschulz WH, Johnson PF, Adashi Ey, Graves BJ, McKnight SL. Isolation of a recombinant copy of the gene encoding C/EBP [published erratum appears in Genes Dev 1994 May 1;8(9):1131]. Genes Dev. 2:1988;786-800.
    • (1988) Genes Dev , vol.2 , pp. 786-800
    • Landschulz, W.H.1    Johnson, P.F.2    Adashi Ey3    Graves, B.J.4    McKnight, S.L.5
  • 13
    • 0024725630 scopus 로고
    • CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells
    • Friedman A, Landschultz W, McKnight S. CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells. Genes Dev. 3:1989;1314-1322.
    • (1989) Genes Dev , vol.3 , pp. 1314-1322
    • Friedman, A.1    Landschultz, W.2    McKnight, S.3
  • 14
    • 0026586526 scopus 로고
    • Reciprocal regulation of adipogenesis by Myc and C/EBP alpha
    • Freytag SO, Geddes TJ. Reciprocal regulation of adipogenesis by Myc and C/EBP alpha. Science. 256:1992;379-382.
    • (1992) Science , vol.256 , pp. 379-382
    • Freytag, S.O.1    Geddes, T.J.2
  • 15
    • 0026048640 scopus 로고
    • The CCAAT/enhancer binding protein and its role in adipocyte differentiation: Evidence for direct involvement in terminal adipocyte development
    • Samuelsson L, Stromberg K, Vikman K, Bjursell G, Enerback S. The CCAAT/enhancer binding protein and its role in adipocyte differentiation: evidence for direct involvement in terminal adipocyte development. EMBO J. 10:1991;3787-3793.
    • (1991) EMBO J , vol.10 , pp. 3787-3793
    • Samuelsson, L.1    Stromberg, K.2    Vikman, K.3    Bjursell, G.4    Enerback, S.5
  • 16
    • 0026511284 scopus 로고
    • Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
    • Lin FT, Lane MD. Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev. 6:1992;533-544.
    • (1992) Genes Dev , vol.6 , pp. 533-544
    • Lin, F.T.1    Lane, M.D.2
  • 18
    • 0026638061 scopus 로고
    • Growth-dependent inhibition of CCAAT enhancer-binding protein (C/EBP alpha) gene expression during hepatocyte proliferation in the regenerating liver and in culture
    • Mischoulon D, Rana B, Bucher NL, Farmer SR. Growth-dependent inhibition of CCAAT enhancer-binding protein (C/EBP alpha) gene expression during hepatocyte proliferation in the regenerating liver and in culture. Mol Cell Biol. 12:1992;2553-2560.
    • (1992) Mol Cell Biol , vol.12 , pp. 2553-2560
    • Mischoulon, D.1    Rana, B.2    Bucher, N.L.3    Farmer, S.R.4
  • 19
    • 0027254753 scopus 로고
    • Differential patterns of expession of three C/EBP isoforms, HNF-1, and HNF-4 after partial hepatectomy in rats
    • Flodby P, Antonson P, Barlow C, Blanck A, Porsch-Hallstrom I, Xanthopoulos KG. Differential patterns of expession of three C/EBP isoforms, HNF-1, and HNF-4 after partial hepatectomy in rats. Exp Cell Res. 208:1993;248-256.
    • (1993) Exp Cell Res , vol.208 , pp. 248-256
    • Flodby, P.1    Antonson, P.2    Barlow, C.3    Blanck, A.4    Porsch-Hallstrom, I.5    Xanthopoulos, K.G.6
  • 20
    • 0028978627 scopus 로고
    • Coexistence of C/EBP alpha, beta, growth-induced proteins and DNA synthesis in hepatocytes during liver regeneration. Implications for maintenance of the differentiated state during liver growth
    • Greenbaum LE, Cressman DE, Haber BA, Taub R. Coexistence of C/EBP alpha, beta, growth-induced proteins and DNA synthesis in hepatocytes during liver regeneration. Implications for maintenance of the differentiated state during liver growth. J Clin Invest. 96:1995;1351-1365.
    • (1995) J Clin Invest , vol.96 , pp. 1351-1365
    • Greenbaum, L.E.1    Cressman, D.E.2    Haber, B.A.3    Taub, R.4
  • 21
    • 0029871328 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-alpha identifies a dominant antiproliferative role for this isoform in hepatocytes
    • Diehl AM, Johns DC, Yang SQ, Lin HZ, Yin M, Matelis LA, et al. Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-alpha identifies a dominant antiproliferative role for this isoform in hepatocytes. J Biol Chem. 271:1996;7343-7350.
    • (1996) J Biol Chem , vol.271 , pp. 7343-7350
    • Diehl, A.M.1    Johns, D.C.2    Yang, S.Q.3    Lin, H.Z.4    Yin, M.5    Matelis, L.A.6
  • 22
    • 0028605954 scopus 로고
    • Expression of the insulin-like growth factor I gene is stimulated by the liver-enriched transcription factors C/EBP alpha and LAP
    • Nolten LA, van Schaik FM, Steenbergh PH, Sussenbach JS. Expression of the insulin-like growth factor I gene is stimulated by the liver-enriched transcription factors C/EBP alpha and LAP. Mol Endocrinol. 8:1994;1636-1645.
    • (1994) Mol Endocrinol , vol.8 , pp. 1636-1645
    • Nolten, L.A.1    Van Schaik, F.M.2    Steenbergh, P.H.3    Sussenbach, J.S.4
  • 23
    • 0028971180 scopus 로고
    • CCAAT/enhancer-binding protein-alpha-dependent transactivation of CYP2C12 in rat hepatocytes
    • Tollet P, Lahuna O, Ahlgren R, Mode A, Gustafsson JA. CCAAT/enhancer-binding protein-alpha-dependent transactivation of CYP2C12 in rat hepatocytes. Mol Endocrinol. 9:1995;1771-1781.
    • (1995) Mol Endocrinol , vol.9 , pp. 1771-1781
    • Tollet, P.1    Lahuna, O.2    Ahlgren, R.3    Mode, A.4    Gustafsson, J.A.5
  • 24
    • 0030021836 scopus 로고    scopus 로고
    • DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family
    • Osada S, Yamamoto H, Nishihara T, Imagawa M. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem. 271:1996;3891-3896.
    • (1996) J Biol Chem , vol.271 , pp. 3891-3896
    • Osada, S.1    Yamamoto, H.2    Nishihara, T.3    Imagawa, M.4
  • 25
    • 0025297353 scopus 로고
    • A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family
    • Akira S, Isshiki H, Sugita T, Tanabe O, Kinoshita S, Nishio Y, et al. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J. 9:1990;1897-1906.
    • (1990) EMBO J , vol.9 , pp. 1897-1906
    • Akira, S.1    Isshiki, H.2    Sugita, T.3    Tanabe, O.4    Kinoshita, S.5    Nishio, Y.6
  • 26
    • 0027530626 scopus 로고
    • Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP)
    • Park EA, Gurney AL, Nizielski SE, Hakimi P, Cao Z, Moorman A, et al. Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP). J Biol Chem. 268:1993;613-619.
    • (1993) J Biol Chem , vol.268 , pp. 613-619
    • Park, E.A.1    Gurney, A.L.2    Nizielski, S.E.3    Hakimi, P.4    Cao, Z.5    Moorman, A.6
  • 27
    • 0029786648 scopus 로고    scopus 로고
    • C/EBP-beta/LAP controls down-regulation of albumin gene transcription during liver regeneration
    • Trautwein C, Rakemann T, Pietrangelo A, Plumpe J, Montosi G, Manns MP. C/EBP-beta/LAP controls down-regulation of albumin gene transcription during liver regeneration. J Biol Chem. 271:1996;22262-22270.
    • (1996) J Biol Chem , vol.271 , pp. 22262-22270
    • Trautwein, C.1    Rakemann, T.2    Pietrangelo, A.3    Plumpe, J.4    Montosi, G.5    Manns, M.P.6
  • 28
    • 0021770917 scopus 로고
    • Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
    • Melton D, Krieg A, Rebagliati M, Maniatis T, Zinn K, Green M. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12:1984;7035-7056.
    • (1984) Nucleic Acids Res , vol.12 , pp. 7035-7056
    • Melton, D.1    Krieg, A.2    Rebagliati, M.3    Maniatis, T.4    Zinn, K.5    Green, M.6
  • 30
    • 0027202690 scopus 로고
    • Molecular basis of reduced albumin gene expression in hepatoma cell lines with different growth rates
    • Cairo G, Lucchini M. Molecular basis of reduced albumin gene expression in hepatoma cell lines with different growth rates. Exp Cel Res. 206:1993;255-260.
    • (1993) Exp Cel Res , vol.206 , pp. 255-260
    • Cairo, G.1    Lucchini, M.2
  • 31
    • 0024435964 scopus 로고
    • Plasma growth hormone pattern regulates epidermal growth factor (EGF) receptor mesenger ribonucleic acid levels and EGF binding in the rat liver
    • Ekberg S, Carlsson L, Carlsson B, Billig H, Jansson J-O. Plasma growth hormone pattern regulates epidermal growth factor (EGF) receptor mesenger ribonucleic acid levels and EGF binding in the rat liver. Endocrinology. 125:1989;2158-2166.
    • (1989) Endocrinology , vol.125 , pp. 2158-2166
    • Ekberg, S.1    Carlsson, L.2    Carlsson, B.3    Billig, H.4    Jansson, J-O.5
  • 32
    • 0020773108 scopus 로고
    • A practical approach for quantitating specific mRNAs by solution hybridization
    • Durnam D, Palmiter R. A practical approach for quantitating specific mRNAs by solution hybridization. Anal Biochem. 131:1983;385-393.
    • (1983) Anal Biochem , vol.131 , pp. 385-393
    • Durnam, D.1    Palmiter, R.2
  • 33
    • 0027363527 scopus 로고
    • Expression and hormonal regulation of the CCAAT enhancer binding protein-alpha during differentiation of rat ovarian follicles
    • Piontkewitz Y, Enerback S, Hedin L. Expression and hormonal regulation of the CCAAT enhancer binding protein-alpha during differentiation of rat ovarian follicles. Endocrinology. 133:1993;2327-2333.
    • (1993) Endocrinology , vol.133 , pp. 2327-2333
    • Piontkewitz, Y.1    Enerback, S.2    Hedin, L.3
  • 35
    • 0027933862 scopus 로고
    • Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: Reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors
    • Rana B, Mischoulon D, Xie Y, Bucher NL, Farmer SR. Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors. Mol Cell Biol. 14:1994;5858-5869.
    • (1994) Mol Cell Biol , vol.14 , pp. 5858-5869
    • Rana, B.1    Mischoulon, D.2    Xie, Y.3    Bucher, N.L.4    Farmer, S.R.5
  • 36
    • 0029029894 scopus 로고
    • The DNA binding activity of C/EBP transcription factors is regulated in the G1 phase of the hepatocyte cell cycle
    • Rana B, Xie Y, Mischoulon D, Bucher NLR, Farmer SR. The DNA binding activity of C/EBP transcription factors is regulated in the G1 phase of the hepatocyte cell cycle. J Biol Chem. 270:1995;18123-18132.
    • (1995) J Biol Chem , vol.270 , pp. 18123-18132
    • Rana, B.1    Xie, Y.2    Mischoulon, D.3    Bucher, N.L.R.4    Farmer, S.R.5
  • 38
    • 0028139273 scopus 로고
    • Dexamethasone inhibits induction of liver tumor necrosis factor-alpha mRNA and liver growth induced by lead nitrate and ethylene dibromide
    • Ledda-Columbano GM, Columbano A, Cannas A, Simbula G, Okita K, Kayano K, et al. Dexamethasone inhibits induction of liver tumor necrosis factor-alpha mRNA and liver growth induced by lead nitrate and ethylene dibromide. Am J Pathol. 145:1994;951-958.
    • (1994) Am J Pathol , vol.145 , pp. 951-958
    • Ledda-Columbano, G.M.1    Columbano, A.2    Cannas, A.3    Simbula, G.4    Okita, K.5    Kayano, K.6
  • 39
    • 0023280552 scopus 로고
    • Growth hormone stimulates sequential induction of c-myc and insulin-like growth factor I expression in vivo
    • Murphy L, Bell G, Friesen H. Growth hormone stimulates sequential induction of c-myc and insulin-like growth factor I expression in vivo. Endocrinology. 120:1987;1806-1812.
    • (1987) Endocrinology , vol.120 , pp. 1806-1812
    • Murphy, L.1    Bell, G.2    Friesen, H.3
  • 40
    • 0028849280 scopus 로고
    • Rapid changes in gene expression after in vivo growth hormone treatment
    • Gronowski AM, Rotwein P. Rapid changes in gene expression after in vivo growth hormone treatment. Endocrinology. 136:1995;4741-4748.
    • (1995) Endocrinology , vol.136 , pp. 4741-4748
    • Gronowski, A.M.1    Rotwein, P.2
  • 41
    • 0026760401 scopus 로고
    • Growth hormone promotes early initiation of hepatocyte growth factor gene expression in the liver of hypophysectomized rats after partial hepatectomy
    • Ekberg S, Luther M, Nakamura T, Jansson J-O. Growth hormone promotes early initiation of hepatocyte growth factor gene expression in the liver of hypophysectomized rats after partial hepatectomy. J Endocrinol. 135:1992;59-67.
    • (1992) J Endocrinol , vol.135 , pp. 59-67
    • Ekberg, S.1    Luther, M.2    Nakamura, T.3    Jansson, J-O.4
  • 42
    • 0030077331 scopus 로고    scopus 로고
    • Liver regeneration 3: Regulation of signal transduction during liver regeneration
    • Diehl AM, Rai RM. Liver regeneration 3: regulation of signal transduction during liver regeneration. FASEB J. 10:1996;215-227.
    • (1996) FASEB J , vol.10 , pp. 215-227
    • Diehl, A.M.1    Rai, R.M.2
  • 43
    • 0028357429 scopus 로고
    • Selective induction of CCAAT/enhancer binding protein isoforms occurs during rat liver development
    • Diehl AM, Michaelson P, Yang SQ. Selective induction of CCAAT/enhancer binding protein isoforms occurs during rat liver development. Gastroenterology. 106:1994;1625-1637.
    • (1994) Gastroenterology , vol.106 , pp. 1625-1637
    • Diehl, A.M.1    Michaelson, P.2    Yang, S.Q.3
  • 44
    • 0027420920 scopus 로고
    • A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: Transcriptional activator lacking antimitotic activity
    • Lin FT, MacDougald OA, Diehl AM, Lane MD. A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. Proc Natl Acad Sci USA. 90:1993;9609-9610.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9609-9610
    • Lin, F.T.1    MacDougald, O.A.2    Diehl, A.M.3    Lane, M.D.4
  • 45
    • 0027276292 scopus 로고
    • High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors
    • Legraverend C, Antonson P, Flodby P, Xanthopoulos KG. High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors. Nucleic Acids Res. 21:1993;1735-1742.
    • (1993) Nucleic Acids Res , vol.21 , pp. 1735-1742
    • Legraverend, C.1    Antonson, P.2    Flodby, P.3    Xanthopoulos, K.G.4
  • 46
    • 0026649510 scopus 로고
    • Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response
    • Alam T, An MR, Papaconstantinou J. Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response. J Biol Chem. 267:1992;5021-5024.
    • (1992) J Biol Chem , vol.267 , pp. 5021-5024
    • Alam, T.1    An, M.R.2    Papaconstantinou, J.3
  • 47
    • 0028848149 scopus 로고
    • Nuclear matrix condensation and c-myc and c-fos expression are specifically altered in culture rat hepatocytes after exposure to cyproterone acetate and phenobarbital
    • Duivenvoorden WC, Schafer R, Pfeifer AM, Piquet D, Maier P. Nuclear matrix condensation and c-myc and c-fos expression are specifically altered in culture rat hepatocytes after exposure to cyproterone acetate and phenobarbital. Biochem Biophys Res Commun. 215:1995;598-605.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 598-605
    • Duivenvoorden, W.C.1    Schafer, R.2    Pfeifer, A.M.3    Piquet, D.4    Maier, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.