Successful treatment of acute subretinal hemorrhage in age-related macular degeneration by combined intravitreal injection of recombinant tissue plasminogen activator and gas

Advances in Therapy

Volumn 14, Issue 5, 1997, Pages 275-280

  Hesse, Lutz ^a,b   Kroll, Peter ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b NONE   (Germany)

Author keywords

Age related macular degeneration; Subretinal hemorrhage; Tissue plasminogen activator

Indexed keywords

ALTEPLASE; THOMAE; UNCLASSIFIED DRUG;

ACUTE DISEASE; AGED; ARTICLE; CASE REPORT; FEMALE; GAS; HUMAN; INTRAVITREAL DRUG ADMINISTRATION; MALE; RETINA DETACHMENT; RETINA HEMORRHAGE; RETINA MACULA AGE RELATED DEGENERATION; VISUAL ACUITY; VITREOUS OPACITY;

EID: 0030680170     PISSN: 0741238X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Bennett AR Folk JC, Blodi C, Klugman M. Factors prognostic of visual outcome in patients with subretinal hemorrhage. Am J Ophthalmol. 1990;109:33-37.
2. DeJuan E, Machemer R. Vitreous surgery for hemorrhagic and fibrous complications of age-related macular degeneration. Am J Ophthalmol. 1988;105:25-29.
3. Hanscom TA, Diddie KR. Early surgical drainage of macular subretinal hemorrhage. Arch Ophthalmol. 1987;105:1722-1723.
4. Wade EC, Flynn HW, Olsen KR, Blumenkranz MS, Nicholson DH. Subretinal hemorrhage management by pars plana vitrectomy and internal drainage. Arch Ophthalmol. 1990;108:973-978.
5. Hesse L, Meitinger D, Schmidt J. Less effect of TPA in subretinal surgery of acute hemorrhage in age-related macular degeneration. Ger J Ophthalmol. 1997; in press.
6. Ibañez HE, Williams DF, Thomas MA, et al. Surgical management of submacular hemorrhage. Arch Ophthalmol. 1995;113:62-69.
7. Herriot W. Intravitreal gas and TPA: an outpatient procedure for subretinal hemorrhage. Presented at the Vitrectomy Meeting; October 10-15,1996; Vail, Colorado.
8. Toth CA, Morse LS, Hjelmeland LM, Landers MB. Fibrin directs early retinal damage after experimental subretinal hemorrhage. Arch Ophthalmol. 1991;109:723-729.
9. Johnson MW, Olsen KR, Hernandez E. Tissue plasminogen activator thrombolysis during surgical evacuation of experimental subretinal hemorrhage. Ophthalmology. 1992;99:515-521.
10. Lewis H, Resnick SC, Flannery JG, Straatsma BR. Tissue plasminogen activator treatment of experimental subretinal hemorrhage. Am J Ophthalmol. 1991;111:197-204.
11. Parver LM, Lincoff H. Geometry of intraocular gas used in retinal surgery. Mod Probl Ophthalmol. 1977;18:338-343.
12. Kamei M, Tano Y, Maeno T, Ikuno Y, Mitsuda H, Yuasa T. Surgical removal of submacular hemorrhage using tissue plasminogen activator and perfluorocarbon liquid. Am J Ophthalmol. 1996;121:267-275.
13. Lewis H. Intraoperative fibrinolysis of submacular hemorrhage with tissue plasminogen activator and surgical drainage. Am J Ophthalmol. 1994;118:559-568.
14. Moriarty AP, McAllister IL, Constable IJ. Initial clinical experience with tissue plasminogen activator (tPA) assisted removal of submacular haemorrhage. Eye. 1995;9:582-588.
15. Morse L, Benner J, Hjelmeland L, Landers M. Fibrinolysis of experimental subretinal haemorrhage without removal using tissue plasminogen activator. Br J Ophthalmol. 1996;80:658-662.
16. Johnson MW, Olsen KR, Hernandez E, Irvine WD, Johnson RN. Retinal toxicity of recombinant tissue plasminogen activator in the rabbit. Arch Ophthalmol. 1990;108:259-263.