Hyperhomocysteinaemia in Black patients with cerebral thrombosis

QJM: An International Journal of Medicine

Volumn 90, Issue 10, 1997, Pages 635-639

  Delport, R ^a   Ubbink, J B ^a   Vermaak, W J H ^a   Rossouw, H ^a   Becker, P J ^b   Joubert, J ^c,d  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^c SEFAKO MAKGATHO HEALTH SCIENCES UNIVERSITY   (South Africa)

^d EPWORTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; HUMAN; HYPERHOMOCYSTEINEMIA; KIDNEY FAILURE; MALE; NEGRO; OCCLUSIVE CEREBROVASCULAR DISEASE; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; STROKE;

EID: 0030679684     PISSN: 00335622     EISSN: None     Source Type: Journal    
DOI: 10.1093/qjmed/90.10.635     Document Type: Article

References (29)

1. Malinow MR, Nieto J, Szklo M, Chambless LE, Bond G. Carotid artery intimal-medial wall thickening and plasma homocysteine in asymptomatic adults. Circulation 1993; 87:1107-13.
2. Stampfer MJ, Malinow R, Willet WC, et al. A prospective study of plasma homocysteine and risk of myocardial infarction in US physicians. JAMA 1992; 268:877-81.
3. Boushey CJ, Beresford SAA, Omenn CS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA 1995; 274:1049-57.
4. Ubbink JB, Delport R, Vermaak WJH. Plasma homocysteine concentrations in a population with low coronary disease prevalence. J Nutr 1996; 126:S1254-7.
5. Isles CG, Milne FJ. Low mortality rate from ischemic heart disease among urban blacks in South Africa. J Clin Hypertens 1987; 3:749-56.
6. Carter LR, Walton SE, Knowles MK, Wing S, Tyroler HA. Social inequality of stroke mortality among US black populations 1968-1987. Ethn Dis 1992; 2:343-51.
7. Osuntokun BO. Stroke in Africans. Afr Med Sci 1977; 6:39-53.
8. Ubbink JB, Serfontein WJ, De Villiers LS. Analytical recovery of protein-bound pyridoxal 5′-phosphate in plasma analysis. J Chromatogr 1986; 375:399-404.
9. Araki A, Sako Y. Determination of free and total homocysteine in human plasma by HPLC with fluorescence detection. J Chromatogr 1987; 422:43-52.
10. Ubbink JB, Vermaak WJH, Bissbort S. Rapid high-performance liquid chromatography assay for total homocysteine levels in human serum. J Chromatogr 1991; 565:441-6.
11. Rosman K. The epidemiology of stroke in an urban black population. Stroke 1986; 17:617-20.
12. Joubert J. The MEDUNSA stroke data bank. An analysis of 304 patients seen between 1986 and 1987. South Afr Med J 1991; 80:567-70.
13. Steenekamp JHB, Simson IW, Theron W. Cardiovascular causes of death at Tshepong Hospital in 1 year, 1989-1990. South Afr Med J 1992; 81:142-6.
14. Milne FJ, James SH, Veriava Y. Malignant hypertension and its renal complications in black South Africans. South Afr Med J 1989; 76:164-7.
15. Whelton PK, Perneger TV, Brancati FL, Klag MJ. Epidemiology and prevention of blood pressure-related disease. J Hypertens 1992; 10 (suppl 7): S77-S84.
16. Flack JM, Neaton JD, Daniels B, Esunge P. Ethnicity and renal disease: lessons from the Multiple Risk Factor Intervention Trial and the Treatment of Mild Hypertension Study. Am J Kidney Dis 1993; 21 (4 Suppl 1): 31-40.
17. Hultberg B, Anderson A, Sterner G. Plasma homocysteine in renal failure. Clin Nephrol 1993; 40:230-4.
18. Brattstrom L, Lindgren A, Israelsson B, Malinow MR, Norrving B, Upson B, Hamfelt A. Hyperhomocysteinemia in stroke; prevalence, cause, and relation to type of stroke and stroke risk factors. Eur J Clin Invest 1992; 22:214-21.
19. Anderson A. Homocysteine and cysteine: determinants of plasma levels in middle-aged and elderly subjects. J Intern Med 1994; 236:633-41.
20. Arnadottir M, Hultberg B, Nilsson-Ehle P, Thysell H. The effect of reduced glomerular filtration rate on plasma total homocysteine concentration. Scand J Clin Lab Invest 1996; 56:41-6.
21. Malinow MR, Kang SS, Taylor LM, Wong PWK, Coull B, Inahara T, Mukerjee D, Sexton G, Upson B. Prevalence of hyperhomocysteinemia in patients with peripheral arterial occlusive disease. Circulation 1989; 79:1180-8.
22. Araki A, Sako Y, Fukushima Y, Matsumoto M, Asada T, Kita T. Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects. Atherosclerosis 1989; 79:139-46.
23. Malinow MR, Levenson J, Giral P, Nieto FJ, Razavian M, Segond P, Simon A. Role of blood pressure, uric acid and hematocrit on plasma homocysteine. Atherosclerosis 1995; 114:175-83.
24. Malinow MR, Ducimetiere P, Luc G, Evans AE, Arveiler D, Cambien F, Upson BM. Plasma homocysteine levels and graded risk for myocardial infarction: findings in two populations at contrasting risk for coronary heart disease. Atherosclerosis 1996; 00:27-34.
25. Verhoef P, Hennekens CH, Malinow MR, Kok FJ, Willett WC, Stampfer MJ. A prospective study of plasma homocysteine and risk of ischemic stroke. Stroke 1994; 25:1924-30.
26. Ubbink JB, Vermaak WJH, Delport R, Van der Merwe A, Becker PJ, Potgieter H. Effective homocysteine metabolism may protect South African Blacks against coronary heart disease. Am J Clin Nutr 1995; 62:802-8.
27. Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia. N Engl J Med 1991; 324:1149-55.
28. Graham I. Interaction between homocysteinemia and conventional risk factors in vascular disease. Eur Heart J 1994; 15 (suppl): 530. Abstract.
29. Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995; 346:1395-8.