Low-molecular-weight heparins and unstable angina – current perspectives

Pathophysiology of Haemostasis and Thrombosis

Volumn 27, Issue 1, 1997, Pages 19-24

  Turpie, Alexander G G ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Heparin; Low molecular weight heparin; Unstable angina

Indexed keywords

DALTEPARIN; ENOXAPARIN; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN;

ANTICOAGULANT THERAPY; CONFERENCE PAPER; CORONARY ARTERY DISEASE; DRUG CHOICE; DRUG EFFICACY; HEPARINIZATION; HUMAN; PRIORITY JOURNAL; THROMBOEMBOLISM; UNSTABLE ANGINA PECTORIS;

ANGINA, UNSTABLE; DRUG THERAPY; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS;

EID: 0030671374     PISSN: 14248832     EISSN: 14248840     Source Type: Journal    
DOI: 10.1159/000217478     Document Type: Article

References (21)

1. Fuster V, Badimon L, Badimon JJ, Chcscbro JH: The pathogenesis of coronary artery disease and the acute coronary syndromes (2)., N Engl J Med 1992;326:310-318.
2. Bashour TT., Myler RK, Andreae GE., Stertzcr SH, Clark DA, Ryan CJ: Current concepts in unstable myocardial ischemia., Am Heart J 1988;115:850-861.
3. Lewis HD Jr, Davis JW, Archibald DG et al: Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina., Results of a Veterans Administration Cooperative Study., N Engl J Med 1983:309:396-403.
4. Cairns JA, Gent M, Singer J: Aspirin, sulfinpyrazone, or both in unstable angina., Results of a Canadian multicenter trial., N Engl J Med 1985;313:1369-1375.
5. Theroux P, Ouimet H, McCans J, Latour JG: Aspirin, heparin or both to treat acute unstable angina., N Engl J Med 1988;319:1105-1111.
6. Ths RISC Group: Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease., Lancet 1990;336:827-830.
7. Theroux P, Waters D, Qiu S, McCans J, de Guise P., Juneau M: Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina., Circulation 1993;88:2045-2048.
8. Cohen M, Adams PC, Parry’ G., Xiong J, Chamberlain D, Wieczorek I: Combination antithrombotic therapy in unstable rest angina and non-Q-wavc infarction in nonprior aspirin users., Primary end points analysis from the ATACS Trial., Antithrombotic Therapy in Acute Coronary Syndromes Research Group., Circulation 1994;89:81-88.
9. Theroux P, Waters D, Lam J, Juneau M, McCans J: Reactivation of unstable angina after the discontinuation of heparin., N Engl J Med 1992;327:141-145.
10. Hirsh J: Heparin., N Engl J Med 1991;324:1565-1574.
11. Hirsh J, Levine MN: Low molecular weight heparin., Blood 1992;79:1-17.
12. Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Gent M, Kelton J: Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin., N Engl J Med 1995;332:1330-1335.
13. Prandoni P, Lensing AW, Buller HR, Carta M, Cogo A, Vigo M, Cas-ara D, Ruol A, ten Cate JW: Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis., Lancet 1992; 339:441-445.
14. Hull RD, Raskob GE, Pineo GF: Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximal-vein thrombosis., N Engl J Med 1992;326:975-982.
15. Siragusa S, Cosmi B, Piovclla F, Hirsh J, Ginsberg JS: Low-molecular-weight heparins and unfraction-ated heparin in the treatment of patients with acute venous thromboembolism: Results of a mcta-analy-sis., Am J Med 1996;100:269-277.
16. Levine M, Gent M, Hirsh J, Leclcrc J, Anderson D., Weitz J, Ginsberg J, Turpie AG: A comparison of low-molecular-weight heparin administered primarily at home with, mfractionated heparin administered in the hospital for proximal deep-vein thrombosis., N Engl J Med 1996; 334:677-681.
17. Koopman MM, Prandoni P, Piovel-la F: Treatment of venous thrombosis with intravenous unfractionatcd heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home., The Tasman Study Group., N Engl J Med 1996, 334:682-687.
18. Gurfinkel EP, Manos EJ, Mejail RI., Cerda MA, Duronto EA, Garcia CN, Daroca AM, Mautner B: Low molecular weight heparin versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia., J Am Coll Cardiol 1995;26:313-318.
19. FRISC Study Group: Low-molecular-weight heparin during instability in coronary artery disease., Lancet 1996;347:561-568.
20. Klein W, Buchwald A, Hillis SE, Monrad S, Sanz G, Turpie AGG, van der Meer J, Olaisson E, Undeland S, Ludwig K for the FRIC Investigators: Comparison of low-molecular-weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease., Circulation 1997;96:61-68.
21. Cohen M, Demers C., Gurfinkel EP., Turpie AGG, Fromcll GJ, Goodman S, Langer A, Califlf RM, Fox KAA., Premmereur J, Bigonzi F for the ESSENCE Study Group: A comparison of low molecular weight heparin with unfractionated heparin for unstable coronary artery disease., N Engl J Med 1997;337:447-452