Advanced non-small cell lung cancer chemotherapy: A randomized trial of two active regimens (MVP and PE)

Cancer Letters

Volumn 119, Issue 2, 1997, Pages 241-247

  Ginopoulos, P ^a,b   Spyropoulos, K ^a   Kardamakis, D ^a   Dougenis, D ^a   Onyenadum, A ^a   Gogos, C H ^a   Solomou, E ^a   Chrysanthopoulos, K ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b NONE   (Greece)

Author keywords

Advanced non small cell lung cancer; Cisplatin; Etoposide; Mitomycin; Vindesine

Indexed keywords

CISPLATIN; ETOPOSIDE; MITOMYCIN; VINDESINE;

ADULT; AGED; ANEMIA; ARTICLE; BONE MARROW SUPPRESSION; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG RESPONSE; DRUG SAFETY; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; NEUROTOXICITY; OTOTOXICITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL TIME; THROMBOCYTOPENIA; VOMITING;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, NON-SMALL-CELL LUNG; CISPLATIN; DOUBLE-BLIND METHOD; ETOPOSIDE; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MITOMYCIN; TREATMENT OUTCOME; VINDESINE;

EID: 0030669703     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00301-7     Document Type: Article

References (24)

1. K. Catsougianni, M. Cogevinas, N. Dontas et al., Mortality from Malignant Diseases in Greece 1960-1985, Hellenic Anticancer Society, Athens, 1990, pp. 28, 29 and 76 (in Greek).
2. J. Samet, The epidemiology of lung cancer, Chest 103 (1993) 20S-29S.
3. L.A. Gloeckker-Ries, B.F. Hankey, B.K. Edwards (National Cancer Institute), Cancer Statistics Review: 1973-1987, NIH Publication No. 90-2789, US Department of Health and Human Services, Bethesda, MD, 1990.
4. C.F. Mountain, Prognostic implications of the international staging system for lung cancer, Semin. Oncol. 3 (1988) 236-245.
5. I. Cojean, T. Le Chevalier, Chemotherapy of stage IIIB and IV non-small-cell lung cancer, Ann. Oncol. 6 (Suppl. 3) (1995) S41-S44.
6. E.C. Holmes, Postoperative chemotherapy for non-small-cell lung cancer, Chest 103 (1993) 30S-34S.
7. P. Drings, Ifosfamide in the treatment of bronchial carcinoma, in: W.B. Brade, E.A. Nagel, S. Seeber (Eds.), Ifosfamide in tumor therapy, Karger, New York, 1987, pp. 294-318.
8. P.A. Bunn, Jr., The expanding role of cisplatin in the treatment of non-small-cell lung cancer. Semin. Oncol. 16 (Suppl. 6) (1989a) S10-S21.
9. P.A. Bunn, Jr., Review of therapeutic trials of carboplatin in lung cancer. Semin. Oncol. 16 (Suppl. 5) (1989b) 27-33.
10. K.R. Durrant, R.J. Berry, F. Ellis et al., Comparison of treatment policies in inoperable bronchial carcinoma, Lancet 1 (1971) 715-719.
11. A.M. Laing, R.J. Berry, C.R. Newman et al., Treatment of inoperable carcinoma of bronchus, Lancet 2 (1975) 1161-1164.
12. Y. Cormier, D. Bergeron, J. La Forge et al., Benefit of polychemotherapy in advanced non-small-cell bronchogenic carcinoma, Cancer 50(5) (1982) 845-849.
13. C.F. Mountain, A new international staging system for lung cancer, Chest 89 (1986) 225-232.
14. G. Panagos, Evaluation of Neoplasmic Disease, 1991, pp. 42-45 (in Greek).
15. L. Crino, M. Clerici, F. Figoli, P. Carlini, G. Ceci, E. Cortesi, A. Carpi, A. Santini, F. Di Costanzo, C. Boni, M. Meacci, E. Cogna, S. Darwich, L. Scarcella, A. Santucci, E. Ballatori, M. Tonato, Chemotherapy of advanced non-small-cell lung cancer: a comparison of three active regimens. A randomized trial of the Italian Oncology Group for Clinical Research (GOIRC), Ann. Oncol. 6 (1995) 347-353.
16. L. Crino, Chemotherapy of advanced non-small-cell lung cancer. The experience of Italian Cooperative Groups, Ann. Oncol. 6 (Suppl. 3)(1995) S45-S47.
17. P.D. Bonomi, D.M. Finkelstein, J.C. Ruckdeschel et al., Combination chemotherapy versus carboplatin or iproplatin followed by combination chemotherapy in stage IV non-small cell lung cancer. An Eastern Cooperative Group Study, J. Clin. Oncol. 7 (1989) 1602-1613.
18. R.J. Gralla, M.G. Kris, M.T. Burke et al., The influence of the addition of mitomycin to vindesine plus cisplatin in a random-assignment trial in 120 patients with non-small cell lung cancer, Proc. Am. Soc. Clin. Oncol. 5 (1986) 182.
19. M. Fukuoka, N. Masuda, K. Furuse et al., A randomized trial in inoperable non-small cell lung cancer: vindesine and cisplatin vs mitocyin, vindesine and cisplatin vs etoposide and cisplatin alternating with vindesine and mitomycin, J. Clin. Oncol. 9 (1991) 606-613.
20. J. Hainsworth, D. Johnson, K. Hande, Chemotherapy of advanced non-small cell lung cancer: a randomized trial of three cisplatin-based chemotherapy, Am. J. Clin. Oncol. (CCT) 12 (4) (1989) 345-349.
21. L.H. Einthorn, P. Loehrer, S.D. Williams et al., Random prospective study of vindesine plus high-dose cisplatin vs vindesine plus cisplatin plus mitomycin C in advanced non-small cell lung cancer, J. Clin. Oncol. 5 (1986) 1037-1043.
22. J.K. Weick, J. Crowley, R.B. Natale et al., A randomized trial of five cisplatin-containing treatments in patients with metastatic non-small cell lung cancer: a Southwest Oncology Group Study, J. Clin. Oncol. 9 (1991) 1157-1162.
23. Ellis, P.A., Smith, I.E., Hardy, J.R., M.C., Talbot, D.C., Ashley, S.E. and Priest, K. (1995) Symptom relief with MVP (mitomycin and cisplatin) chemotherapy in advanced non-small-cell lung cancer. Br. J. Cancer 71, 366-370.
24. F.A. Shepherd, Future directions in the treatment of non-small-cell lung cancer, Semin. Oncol. 21 (3) (Suppl. 4) (1994) 48-62.