Antinociceptive effect of intrathecal neostigmine evaluated in rats by two different pain models

Brazilian Journal of Medical and Biological Research

Volumn 30, Issue 10, 1997, Pages 1225-1231

  Prado, W A ^a   Goncalves A S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antinociception; Cholinergic antinociception; Neostigmine

Indexed keywords

FORMALDEHYDE; NEOSTIGMINE;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; INTRATHECAL DRUG ADMINISTRATION; MALE; NONHUMAN; PAIN ASSESSMENT; RAT; TAIL FLICK TEST;

ANIMALIA;

EID: 0030669566     PISSN: 0100879X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0100-879X1997001000014     Document Type: Article

References (34)

1. Green PG & Kitchen I (1986). Antinociception opioids and the cholinergic system. Progress in Neurobiology. 26: 119-146.
2. Yaksh TL, Dirksen R & Harty GJ (1985). Antinociceptive effects of intrathecally injected cholinomimetic drugs in the rat and cat. European Journal of Pharmacology, 117: 81-88.
3. Gillberg PG, Gordh Jr T, Hartvig P, Pettersson J & Post C (1989). Characterisation of the antinociception induced by intrathecally administered carbachol. Pharmacology and Toxicology. 64: 340-343.
4. Smith MD, Nha JY & Buccafusco JJ (1989). Antinociceptive effects of spinal cholinergic stimulation: interaction with substance P. Life Sciences. 45: 1255-1261.
5. Zhuo M & Gebhart GF (1991). Tonic cholinergic inhibition of spinal mechanical transmission. Pain. 46: 211-222.
6. McIntosh FC (1941). The distribution of acetylcholine in the peripheral and the central nervous system. Journal of Physiology, 99: 436-442.
7. Feldberg W & Vogt M (1948). Acetylcholine synthesis in different regions of the central nervous system. Journal of Physiology, 107: 372-381.
8. Kasa P, Mann SP & Hebb CO (1970). Localization of cholinacetyltransferase. Nature, 226: 812-816.
9. Roessmann U & Friede RL (1967). The segmental distribution of acetylcholinesterase in the cat spinal cord. Journal of Anatomy. 101: 27-32.
10. 3H]acetylcholine binding sites in the cervical spinal cord of man and some other species. Neuroscience Letters, 90: 197-202.
11. 3H] quinuclidinyl benzylate to muscarinic receptors in the spinal cord of the sheep. Journal of Veterinary Pharmacology and Therapeutics. 14: 345-350.
12. Sherriff FE, Henderson Z & Morrison JF (1991). Further evidence for the absence of a descending cholinergic projection to the spinal cord in the rat. Neuroscience Letters, 128: 52-56.
13. Pedigo NW, Dewey WL & Harris LS (1975). Determination and characterisation of the antinociceptive activity of intraventricularly administered acetylcholine in mice. Journal of Pharmacology and Experimental Therapeutics. 193: 845-852.
14. Hood DD & Eisenach JC (1994). Phase I safety assessment of spinal neostigmine in volunteers. Anesthesiology, 81: 26 (Abstract).
15. Hood DD & Eisenach JC (1994). Side effects and analgesia from spinal neostigmine through a Whitacre needle. Anesthesiology, 81:27 (Abstract).
16. Lauretti GL, Reis MP, Prado WA & Klamt JG (1996). Dose-response study of intrathecal morphine versus intrathecal neostigmine, their combination, or placebo for postoperative analgesia in patients undergoing anterior and posterior vaginoplasty. Anesthesia and Analgesia, 82: 1182-1187.
17. Klamt JG, Reis MP, Barbieri Neto J & Prado WA (1996). Analgesic effect of subarachnoid neostigmine in two patients with cancer pain. Pain, 66: 389-391.
18. Lauretti GL & Lima IC (1996). The effects of intrathecal neostigmine on somatic and visceral pain: improvement by association with a peripheral anticholinergic. Anesthesia and Analgesia, 82: 617-620.
19. Wood PL (1984). Analgesics: Neurochemical, Behavioural and Clinical Perspectives. Raven Press, New York, 175-189.
20. Dubuisson D & Dennis SG (1977). The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stimulation in rats and cats. Pain. 4: 161-174.
21. Shibata M, Ohkubo T, Takahashi H & Inoki R (1989). Modified formalin test: characteristic biphasic pain response. Pain, 38: 347-352.
22. Zimmermann M (1983). Ethical guidelines for investigation of experimental pain in conscious animals. Pain, 16: 109-110.
23. Yaksh TL & Rudy TA (1976). Chronic catheterization of the spinal subarachnoid space. Physiology and Behavior, 17: 1031-1036.
24. Wheeler-Aceto H & Cowan A (1991). Standardization of the rat paw formalin test for the evaluation of analgesics. Psychopharmacology, 104: 35-44.
25. Malmberg AB & Yaksh TL (1993). Pharmacology of the spinal action of ketorolac, morphine, ST-91, U50488, and LPIA on the formalin test and an isobolographic analysis of the NSAID interaction. Anesthesiology, 79: 270-281.
26. Wiertelak EP, Furness LE, Watkins LR & Maier SF (1994). Illness-induced hyperalgesia is mediated by a spinal NMDA-nitric oxide cascade. Brain Research. 664: 9-16.
27. Dickenson AH & Sullivan AF (1987). Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones. Neuroscience Letters, 83: 207-211.
28. Ryan SM, Watkins LR, Mayer DJ & Maier SF (1985). Spinal pain suppression mechanisms may differ for phasic and tonic pain. Brain Research, 334: 172-175.
29. Haley JE, Sullivan AF & Dickenson AH (1990). Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in rat. Brain Research, 518: 218-226.
30. Coderre TJ & Melzack R (1992). The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury. Journal of Neuroscience. 12: 3665-3675.
31. Malmberg AB & Yaksh TL (1992). Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science, 257: 1276-1279.
32. Ohkubo T, Shibata M, Takahashi H & Inoki R (1990). Roles of substance P and somatostatin in transmission of nociceptive information induced by formalin in spinal cord. Journal of Pharmacology and Experimental Therapeutics, 252: 1261-1268.
33. Coderre TJ & Melzack R (1991). Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids. Neuroscience Letters, 131: 71-74.
34. Klamt JG, Slullitel A, Garcia LV & Prado WA (1997). Postoperative analgesic effect of intrathecal neostigmine and its influence on spinal anaesthesia. Anaesthesia, 52: 547-551.