An oxytetracycline residue depletion study to assess the physiologically based pharmokinetic (PBPK) model in farmed Atlantic salmon

Canadian Veterinary Journal

Volumn 38, Issue 10, 1997, Pages 645-646

  Brocklebank, John R ^a   Namdari, Rostam ^b   Law, Francis C P ^b  

^a Brocklebank Mobile Vet Serv Ltd   (Canada)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTETRACYCLINE;

BACTERIAL INFECTION; DEPLETION; ENVIRONMENTAL TEMPERATURE; FISH; NONHUMAN; PHYSIOLOGY; RESIDUE ANALYSIS; RISK ASSESSMENT; SALMON; SAMPLING; SHORT SURVEY; TISSUE SECTION; WATER TEMPERATURE;

ANIMALS; ANTI-BACTERIAL AGENTS; AQUACULTURE; CANADA; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESIDUES; FISHERIES; MODELS, BIOLOGICAL; OXYTETRACYCLINE; RANDOM ALLOCATION; SALMON; TEMPERATURE;

EID: 0030669324     PISSN: 00085286     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Agriculture and Agri-Food Canada. Compendium of Medicating Ingredients Brochure, Section 35A. Feeds and Fertilizer Division, Canada Department of Agriculture and Agri-Food. 5th ed, 1984 Available from Supply and Services Canada, Canadian Government Publication Centre, Ottawa, Ontario K1A 0S9.
2. Law FCP. A physiologically based pharmocokinetic model of oxytetracycline for salmonids. Proc 8th Symp Vet Pharmacol Ther, Guelph, Ontario 1992: 33-43.
3. Salte R, Liestol K. Drug withdrawal from farmed fish. Depletion of oxytetracycline, sulfadiazine and trimethoprim from muscular tissue of rainbow trout (Salmo gairdneri) Acta Vet Scand 1993; 24: 418-430.