Selective, orally active 5-HT(1D) receptor agonists as potential antimigraine agents

Journal of Medicinal Chemistry

Volumn 40, Issue 22, 1997, Pages 3501-3503

  MacLeod, A M ^a   Street, L J ^a   Reeve, A J ^a   Jelley, R A ^a   Sternfeld, F ^a   Beer, M S ^a   Stanton, J A ^a   Watt, A P ^a   Rathbone, D ^a   Matassa, V G ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (3 FLUOROPHENYL)ETHYL] 4 [3 [5 (1,2,4 TRIAZOL 4 YL) 1H INDOL 3 YL]PROPYL]PIPERAZINE; ANTIMIGRAINE AGENT; RIZATRIPTAN; SEROTONIN AGONIST; SUMATRIPTAN; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ARTICLE; CORONARY ARTERY CONSTRICTION; DRUG BIOAVAILABILITY; DRUG CONFORMATION; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; HUMAN; MIGRAINE; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; TABLET FORMULATION; THORAX PAIN; VERTIGO;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; MIGRAINE DISORDERS; RECEPTOR, SEROTONIN, 5-HT1D; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SPECIES SPECIFICITY;

EID: 0030669050     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9704560     Document Type: Article

References (20)