Non-genotoxic effects of selected pesticides and their disinfection by-products on gap junctional intercellular communication

Ozone: Science and Engineering

Volumn 19, Issue 4, 1997, Pages 351-369

  Upham, Brad L ^a   Boddy, Brad ^b   Xing, Xiaoshi ^b   Trosko, James E ^a   Masten, Susan J ^b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

Author keywords

2,4 D; Alachlor; Atrazine; Carbofuran; Chlorination; Chlorination by products; Epigenetic toxicity; Gap Junction Intercellular communication; Lindane; Non Genotoxic mechanisms of cellular injury; Ozonation by products; Ozone; Pesticides; Rat liver epithelial cells

Indexed keywords

EID: 0030668978     PISSN: 01919512     EISSN: None     Source Type: Journal    
DOI: 10.1080/01919519708547298     Document Type: Article

References (57)

1. C.D. ADAMS; S.J. RANDTKE, "Removal of Atrazine from Drinking Water by Ozonation", J. Amer. Water Works Assoc. 84:91-102 (1992).
2. ANON. Ground Water Monitor 240 (1988).
3. P.S. BAILEY, In: Ozonation in Organic Chemistry, H.H. Wasserman (ed.), (New York, NY: Academic Press, 1982), pp. 1-469.
4. R.M. BEHKI; S.V. KHAN, "Degradation of Atrazine by Pseudomonas: N-Dealkylation and Dehalogenation of Atrazine and its Metabolites", J. Agric. Food Chem. 34:746-749 (1988).
5. E. BORENFREUND; J. PUERNER, "Toxicity Determined In Vitro by Morphological Alterations and Neutral Red Absorption", Toxicol. Lett. 24:119-124 (1985).
6. D.J. BRUSICK, "An Assessment of the Genetic Toxicity of Atrazine: Relevance to Human Health and Environmental Effects", Mutat. Res., 317:133-144 (1994).
7. R.J. BUSHWAY; H.L. HURST; L.B. PERKINS; L. TIAN; C. GUIBERTEAU CABANILLAS; B.E.S. YOUNG; H.S. JENNINGS, "Atrazine, Alachlor, and Carbofuran contamination of Well Water in Central Maine", Bull. Environ. Contam. Toxicol. 49:1-9 (1992).
8. G. CERUTTI; A. GEROSE; R. ZAPPAVIGNA; G. PIROVANO "Residues of organochlorine pesticides in human milk.", Latte 1:317-321 (1976).
9. A.K. CHATURVEDI, "Toxicological Evaluation of Mixtures of Ten Widely Used Pesticides", J. Appl. Toxicol. 13:183-188 (1993).
10. M.H. EL-FOULY; J.E. TROSKO; C.C. CHANG, "Scrape-Loading and Dye Transfer: A Rapid and Simple Technique to Study Gap Junction Intercellular Communication", Exp. Cell Res. 168:422-430 (1987).
11. A.J. ELLIS; F.G. SOPER, "Studies of N-halogeno Compounds. VI. The Kinetics of Chlorination of Tertiary Amines. J. Chem. Soc. 1750-1755 (1954).
12. R.J. FITZGERALD; H. YAMASAKI, "The Role of Inhabited Gap Junction Function in Carcinogenesis", In Vitro Toxicol. 3:87-89 (1990).
13. X. GUAN; W.J. BONNEY; R.J. RUCH (1995), "Changes in Gap Junction Permeability, Gap Junction Number, and Connexin43 Expression in Lindane-Treated Rat Liver Epithelial Cells", Toxicol. Appl. Pharmacol. 130:79-86 (1995).
14. T.J. GISH; A.T. ISENSEO; T.G. NASH; C.S. HELLING, "Impact of Pesticides on Shallow Groundwater Quality", Transactions of the ASAE, 34:1745-1753 (1991).
15. W.H. GLAZE; J.B. ANDELMAN; R.J. BULL; R.B. CONOLLY; C.D. HERTZ; R.D. HOOD; R.A. PEGRUM, "Determining Health Risks Associated with Disinfectants and Disinfection By-Products: Research Needs", J. Am. Water Works Assoc, 85:53-56 (1993).
16. X. GUAN; W.J. BONNEY; R.J. RUCH, "Changes in Gap Junction Permeability, Gap Junction Number, and Connexin43 Expression in Lindane-Treated Rat Liver Epithelial Cells", Toxicol. Appl. Pharmacol. 130:79-86 (1995).
17. G.R. HALLBERG, "Agricultural Chemicals in Groundwater: Extent and Implications", Amer. J. Alternative Agric. 2:3-15 (1987).
18. J.L. HARIDON; M. FERNANDEZ; V. FERRIER; J. BELLAN, "Evaluation of the Genotoxicity of N-Nitrosoatrazine, N-Nitrosodiethanolamine and their Precursors In Vivo Using the New Micronucleus Test", Water Research, 27:855-862 (1993).
19. C. HIRANO; K. KATADA, "Residues of chlorinated hydrocarbon insecticides in some components of Koso river in Kochi 5 years after their prohibition of their use", Bochu Kagaku 40:132-137 (1975).
20. J. HOIGNÉ; H. BADER, "Rate Constants of Reactions of Ozone with Organic and Inorganic Compounds in Water. II. Dissociating Organic Compounds," Water Res., 17:173-183 (1983a).
21. J. HOIGNÉ; H. BADER, "Rate Constants of Reactions of Ozone with Organic and Inorganic Compounds in Water. I. Non-dissociating Organic Compounds," Water Res., 17:173-183 (1983b).
22. IARC, "Halogenated Hydrocarbons", IARC Monog. Eval. Carcinog. Risk Chem. Hum. 20:195-239 (1979).
23. M.A. IBRAHIM; G.G. BOND; T.A. BURKE; P. COLE; F.N. DOST; P.E. ENTERLINE; M. GOUGH; R.S. GREENBERG; W.E. HALPERIN; E. MCCONNELL; I.C. MUNRO; J.A. SWENBERG; J.D. GRAHAM, "Weight of the Evidence on the Human Carcinogenicity of 2,4-D", Environ. Health Perspectives, 96:213-222 (1991).
24. J.D. JOHNSON; J.N. JENSEN, "THM and TOX Formation: Routes, Rates, and Precursors", J. Am. Water Works Assoc. 78:156-162 (1986).
25. Y. KANNO, "Modulation of cell communication and carcinogenesis," Japan. J. Physiol., 35:693-701 (1985).
26. M. KITAYAMA; H. KANESHIMA; H. OGAWA "Prevention of poisoning by agricultural chemicals. XXII. residues of agricultural chemicals in rivers of agricultural areas", Hokkaidoritsu Eisei Kenkyusho Ho 26:62-66 (1975).
27. J.E. KLAUNIG; R.J. RUCH, "Comparative Effects of Phenobarbitol, DDT, and Lindane on Mouse Hepatocyte Gap Junctional Intercellular Communication", Toxicol. Appl. Pharmacol., 102:553-563 (1990).
28. W.R. LOEWENSTEIN, "Permeability of membrane Junctions,", Ann. N.Y. Acad. Sci., 137:441-472 (1966).
29. W.R. LOEWENSTEIN, "Junctional Intercellular Communication and the Control of Growth", Biochem. Biophys. Acta. 560:1-65 (1979).
30. R.A. LARSON, "Reactions with Disinfectants", in: Environmental Organic Chemistry (Boca Raton, FL: Lewis Publishers, 1994), pp. 275-358.
31. W.L. MARCUS, "Alachlor: Health Advisory," Toxicol. Indus. Health, 3:383-396 (1987).
32. E.G. MEANS, III; S.W KRASNER, "D-DBP Regulation: Issues and Ramifications", J. Am. Water Works Assoc., 85:68-73 (1979).
33. R.J. MILTNER; H.M. SHUKAIRY; R.S. SUMMERS, "Disinfection By-Product Formation and Control by Ozonation and Biotreatment", J. Am. Water Works Assoc, 84:53-62 (1992).
34. J.C. MORRIS, "Kinetics of reactions between aqueous chlorine and nitrogen compounds", In: Principles and Applications of Water Chemistry, S.D. Faust and J.V. Hunter (eds.), (New York, NY: John Wiley and Sons, 1967), pp. 22-53.
35. M. OCHAI; T. HANYA, "Alpha and gamma-BHC in Tamagawa river water, Japan", Environ. Pollut. 11:161-166 (1976).
36. J.C. SAEZ; M.V.L. BENNETT; D.C. SPRAY, "Carbon Tetrachloride at Hepatotoxic Levels Blocks Reversibly Gap Junctions Between Rat Hepatocytes", Science, 236:967-970 (1987).
37. P. SAGELSDORFF; W.K. LUTZ; C. SCHLATTER, "The Relevance of Covalent Binding to Mouse Liver DNA to the Carcinogenic Action of Hexachlorocyclohexane Isomers", Carcinogenesis, 4:1267-1273 (1983).
38. M. SAI; M. KITAYAMA, "Prevention of poisoning by agricultural chemicals XIX. Organopesticide residues in water and soil" , Hokkaidoritsu Eisei Kekyushu Ho. 24:126-127(1974).
39. C. SCHROTER; W. PARZEFALL; H. SCHROTER; R. SCHULTE-HERMANN, "Dose-Response Studies on the Effects of α-, β-and γ-Hexachlorocyclohexane on Putative Preneoplastic Foci, Monooxygenases, and Growth in Rat Liver", Cancer Research, 47:80-88 (1987).
40. T. STEVENS; D.D. SUMNER, "Herbicides", In Handbook of Pesticide Technology, Vol. 3, W.J. Hayes E.R. Laws (eds.) (New York, NY: Academic Press, New York, 1991), pp. 1317-1408.
41. J.T. STEVENS; C.B. BRECKENRIDGE; L.T. WETZEL; J.H. GILLIS; L.G. LUEMPERT, III; J.C. ELDRIDGE, "Hypothesis for mammary tumorigenesis in Sprague Dawley rats exposed to certain triazine herbicides. J. Toxicol. Environ. Health, 43:139-153 (1994).
42. R.W. TENNANT; B.H. MARGOLIN; M.P. SHEEL; E. ZIEGER; J.K. HASEMAN; J. SPALDING; W. CASPARY; M. RESNICK; S. STASIEWICZ; B. ANDERSON; R. MINOR, "Prediction of Chemical Carcinogenicity in Rodents from in vitro Genetic Toxicity Assays", Science, 236:933-941 (1987).
43. A.K. THAKUR; L.T. WETZEL; M.O. TISDEL; J.T. STEVENS, "Comparison of the Potential Effects of Atrazine on the Development of Mammary, Pituitary, Uterine, and Ovarian Tumors in Sprague Dawley and Fisher 344 Female Rats", Toxicologist 12:380 (1992).
44. J.E. TROSKO; C.C. CHANG, "Non-genotoxic Mechanisms in Carcinogenesis: Role of Inhibited Intercellular Communication," Banbury Report 31: New Directions in the Qualitative and Quantitative Aspects of Carcinogen Risk Assessment (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1988), pp. 139-170.
45. J.E. TROSKO; C.C. CHANG; B.V. MADHUKAR, "In Vitro Analysis of Intercellular Communication. Implications for Biologically Based Risk Assessment Models For Chemical Exposure", Toxic. In Vitro, 4:635-643 (1990).
46. J.E. TROSKO; C.C. CHANG; B.V. MADHUKAR; E. DUPONT, "Oncogenes, Tumor Suppressorgenes and Intercellular Communication in the 'Oncogeny as Partially Blocked Ontogeny' hypothesis," In New Frontiers in Cancer Causation, O.H. Iversen, ed., (Washington, DC: Tayler and Francis Publishers, 1993), pp 181-197.
47. J.E. TROSKO; C.C. CHANG; B.V. MADHUKAR; J.E. KLAUNIG, "Chemical, Oncogene, and Growth Factor Inhibition of Gap Junctional Intercellular Communication: An Integrative Hypothesis of Carcinogenesis", Pathobiology, 58:265-278 (1991).
48. B.L. UPHAM; S.J. MASTEN; B.R. LOCKWOOD; J.E. TROSKO, "Nongenotoxic Effects of Polycyclic Aromatic Hydrocarbons and their Ozonation By-Products on the Intercellular Communication of Rat Liver Epithelial Cells", Fundam. Appl. Toxicol. 23:470-475 (1994).
49. B.L. UPHAM; J.J. YAO; J.E. TROSKO; S.J. MASTEN, "Determination of the Efficacy of Ozone Treatment Systems Using a Gap Junction Intercelluar Communication Bioassay", Environ. Sci. Technol. 29:2923-2928 (1995).
50. U.S. EPA, "Carbofuran", In: Health Advisory for 16 Pesticides, U.S. EPA-Office of Drinking Water, Washington, DC, pp 1-15 (1987). Available from Natl. Tech. Info. Service, Springfield, VA as Rept. No. PB87-200176.
51. U.S. EPA, Report No. EPA-600/4-88/039, (Cincinnati, OH: U.S. EPA, Environmental Monitoring Systems Laboratory, pp. 32-356 (1988). Available from Natl. Tech. Info. Service, Springfield, VA as Rept. No. PB 89-220461.
52. M.P. WILSON; E.P. SAVAGE; D.D. ADRION; M.J. AARONSON; T.J. KEEL; D.H. HAMAR; J.T. TESSARI, "Groundwater Transport of the Herbicide, Atrazine, Weld County, Colorado", Bull. Environ. Contam. Toxicol. 39:807-814 (1987).
53. T. YAMADA; S. SUGIYAMA; H. NODA; Y. MITSUKINI; M. YOSHIMURA, Organochlorinated pesticides (BHC) in human organs and tissues", Nippon Hoigaku Zasshi 30:416-426 (1976).
54. H. YAMASAKI, "Gap Junctional Intercellular Communication and Carcinogenesis", Carcinogenesis, 11:1051-1058 (1990).
55. R.S.H. YANG; E.J. RAUCKMANN, "Toxicological Studies of Chemical Mixtures of Environmental Concern at the National Toxicology Program: Health Effects of Groundwater Contaminants", Toxicology, 47:15-34 (1987).
56. C.C.D. YAO; HAAG, W.R., "Rate constants for direct reactions of ozone with several drinking water contaminants", Water Res., 25:761-773 (1991).
57. M.J. ZEILMAKER; H. YAMASAKI, "Inhibition of Junctional Intercellular Commumcation as a Possible Short-Term Test to Detect Tumor-Promoting Agents: Results with Nine Chemicals Tested by Dye Transfer Assay in Chinese Hamster V79 Cells", Cancer Research, 46:6180-6186 (1986).