Hydrophobicity parameters determined by reversed-phase liquid chromatography. XII. Comparison of capacity factors and octane/methanol- water partition coefficients for monosubstituted pyrazines, and effect of octanol added to both partitioning systems

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 10, 1997, Pages 1653-1658

  Yamagami, Chisako ^a   Iwasaki, Kaname ^a   Ishikawa, Ayako ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Capacity factor; Hydrogen bond effect; Hydrophobicity; Octanol effect; Partition coefficient

Indexed keywords

METHANOL; OCTANOL; PYRAZINE;

ARTICLE; CONCENTRATION RESPONSE; DRUG DESIGN; HYDROGEN BOND; HYDROPHOBICITY; PARTITION COEFFICIENT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0030668789     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.1653     Document Type: Article

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